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公开(公告)号：WO9003979A3
公开(公告)日：1990-05-17
申请号：PCT/US8904312
申请日：1989-10-02
Applicant: ARCH DEV CORP
Inventor： LIAO SHUTSUNG , PATAKI JOHN , HARVEY RONALD G
IPC: A61K31/045 , A61K31/05 , A61K31/12 , A61K31/22 , C07C39/17 , C07C45/51 , C07C49/657 , C07C49/665 , C07C49/747 , C07C49/753 , C07C49/792 , C07J1/00 , C07J63/00
CPC classification number: C07J63/008 , A61K31/045 , A61K31/05 , A61K31/12 , A61K31/22 , C07C39/17 , C07C45/513 , C07C45/516 , C07C49/657 , C07C49/665 , C07C49/747 , C07C49/753 , C07C49/792 , C07C2603/26 , C07J1/0055 , C07J1/0059 , C07J1/007 , C07J1/0088
Abstract: Disclosed are novel classes of anti-androgens including dihydrophenanthrene derivatives, their method of synthesis and their use in treating disorders associated with excessive androgenic activities.
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公开(公告)号：AU4349889A
公开(公告)日：1990-05-01
申请号：AU4349889
申请日：1989-10-02
Applicant: ARCH DEV CORP
Inventor： LIAO SHUTSUNG , PATAKI JOHN , HARVEY RONALD G
IPC: A61K31/015 , A61K31/05 , A61K31/12 , C07C33/34 , C07C33/36 , C07C39/17 , C07C49/105 , C07C49/792 , C07C69/017 , C07J1/00 , C07J11/00 , C07J63/00
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公开(公告)号：AU621947B2
公开(公告)日：1992-03-26
申请号：AU4349889
申请日：1989-10-02
Applicant: ARCH DEV CORP
Inventor： LIAO SHUTSUNG , PATAKI JOHN , HARVEY RONALD G
IPC: A61K31/015 , A61K31/05 , A61K31/12 , C07C33/34 , C07C33/36 , C07C39/17 , C07C49/105 , C07C49/792 , C07C69/017 , C07J1/00 , C07J11/00 , C07J63/00
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公开(公告)号：CA1338667C
公开(公告)日：1996-10-22
申请号：CA614576
申请日：1989-09-29
Applicant: ARCH DEV CORP
Inventor： LIAO SHUTSUNG , PATAKI JOHN , HARVEY RONALD G
IPC: G01N33/50 , A61K31/00 , A61K31/045 , A61K31/05 , A61K31/12 , A61K31/22 , A61K31/565 , A61P5/26 , C07C22/04 , C07C33/18 , C07C35/42 , C07C35/44 , C07C39/12 , C07C39/17 , C07C45/51 , C07C49/115 , C07C49/225 , C07C49/657 , C07C49/665 , C07C49/747 , C07C49/753 , C07C49/792 , C07C69/00 , C07J1/00 , C07J63/00 , C07C33/00 , A61K31/56
Abstract: Disclosed are novel classes of anti-androgens including dihydrophenanthrene derivatives, their method of synthesis and their use in treating disorders associated with excessive androgenic activities. Preferred derivatives include 1-¢2-(9,10-dihydrophenanthryl)!-1-ethanol; 6,7,16,17-tetrahydro-15H-cyclopenta¢a!-phenanthren-17-ol; 1-¢2-(9(or 10)-methyl-9,10-dihydrophenanthryl)!-1-ethanol; 2-hydroxy-9,10-dihydrophenanthrene; 6,7,16,17-tetrahydro-15H-cyclopenta¢a!pehanthren-17-one; 4'-oxo-7,8-cyclohexeno-9,10-dihydrophenanthren-1-ol; and 4'-oxo-7,8-cyclohexeno-phenanthren-1-ol. Also provided by the invention are the corresponding derivatives wherein a free hydroxyl group has been replaced with an acetate or a propionate moiety.
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Patent Agency Ranking
公开(公告)号：DK54791A
公开(公告)日：1991-05-22
申请号：DK54791
申请日：1991-03-26
Applicant: ARCH DEV CORP
Inventor： LIAO SHUTSUNG , PATAKI JOHN , HARVEY RONALD G
IPC: G01N33/50 , A61K31/00 , A61K31/045 , A61K31/05 , A61K31/12 , A61K31/22 , A61K31/565 , A61P5/26 , C07C22/04 , C07C33/18 , C07C35/42 , C07C35/44 , C07C39/12 , C07C39/17 , C07C45/51 , C07C49/115 , C07C49/225 , C07C49/657 , C07C49/665 , C07C49/747 , C07C49/753 , C07C49/792 , C07C69/00 , C07J1/00 , C07J63/00 , C07C33/34 , C07C33/36 , C07C69/157
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公开(公告)号：DK173840B1
公开(公告)日：2001-12-10
申请号：DK54791
申请日：1991-03-26
Applicant: ARCH DEV CORP
Inventor： LIAO SHUTSUNG , PATAKI JOHN , HARVEY RONALD G
IPC: G01N33/50 , A61K31/00 , A61K31/045 , A61K31/05 , A61K31/12 , A61K31/22 , A61K31/565 , A61P5/26 , C07C22/04 , C07C33/18 , C07C35/42 , C07C35/44 , C07C39/12 , C07C39/17 , C07C45/51 , C07C49/115 , C07C49/225 , C07C49/657 , C07C49/665 , C07C49/747 , C07C49/753 , C07C49/792 , C07C69/00 , C07J1/00 , C07J63/00 , C07C33/34 , C07C33/36 , C07C69/157
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公开(公告)号：ES2059779T3
公开(公告)日：1994-11-16
申请号：ES89310063
申请日：1989-10-02
Applicant: ARCH DEV CORP
Inventor： LIAO SHUTSUNG , HARVEY RONALD G , PATAKI JOHN
IPC: G01N33/50 , A61K31/00 , A61K31/045 , A61K31/05 , A61K31/12 , A61K31/22 , A61K31/565 , A61P5/26 , C07C22/04 , C07C33/18 , C07C35/42 , C07C35/44 , C07C39/12 , C07C39/17 , C07C45/51 , C07C49/115 , C07C49/225 , C07C49/657 , C07C49/665 , C07C49/747 , C07C49/753 , C07C49/792 , C07C69/00 , C07J1/00 , C07J63/00 , A61K31/56 , C07C33/34 , C07C33/36 , C07C49/237 , C07C69/017 , C07D303/04
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公开(公告)号：AT93726T
公开(公告)日：1993-09-15
申请号：AT89310063
申请日：1989-10-02
Applicant: ARCH DEV CORP
Inventor： LIAO SHUTSUNG , HARVEY RONALD G , PATAKI JOHN
IPC: A61K31/56 , C07C33/34 , C07C39/17 , C07C49/225 , C07C49/237 , C07C69/017 , C07J1/00 , C07J63/00
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公开(公告)号：DK54791D0
公开(公告)日：1991-03-26
申请号：DK54791
申请日：1991-03-26
Applicant: ARCH DEV CORP
Inventor： LIAO SHUTSUNG , PATAKI JOHN , HARVEY RONALD G
IPC: G01N33/50 , A61K31/00 , A61K31/045 , A61K31/05 , A61K31/12 , A61K31/22 , A61K31/565 , A61P5/26 , C07C22/04 , C07C33/18 , C07C35/42 , C07C35/44 , C07C39/12 , C07C39/17 , C07C45/51 , C07C49/115 , C07C49/225 , C07C49/657 , C07C49/665 , C07C49/747 , C07C49/753 , C07C49/792 , C07C69/00 , C07J1/00 , C07J63/00 , C07C33/34 , C07C33/36 , C07C69/157
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