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公开(公告)号：AU2011240808A1
公开(公告)日：2012-11-29
申请号：AU2011240808
申请日：2011-04-11
Applicant: ARRAY BIOPHARMA INC
Inventor： BOYS MARK LAURENCE , BURGESS LAURENCE E , GRONEBERG ROBERT D , HARVEY DARREN M , HUANG LILY , KERCHER TIMOTHY , KRASER CHRISTOPHER F , LAIRD ELLEN , TARLTON EUGENE , ZHAO QIAN
IPC: C07D487/04 , A61K31/519 , A61P29/00 , A61P37/00
Abstract: Compounds of Formula I: (Formula should be inserted here) and stereoisomers and pharmaceutically acceptable salts and solvates thereof in which R, R, R, R, R, R, R, X and X have the meanings given in the specification, are inhibitors of one or more JAK kinases and are useful in the treatment of autoimmune diseases, inflammatory diseases, rejection of transplanted organs, tissues and cells, as well as hematologic disorders and malignancies and their co-morbidities.
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公开(公告)号：UY34388A
公开(公告)日：2014-04-30
申请号：UY34388
申请日：2012-10-11
Applicant: ARRAY BIOPHARMA INC
Inventor： BOYS MARK LAURENCE , HICKEN ERIK JAMES , MUNSON MARK C , EARY C TODD , HACHE BRUNO P , GRONEBERG ROBERT D , HARVEY DARREN M , KRASER CHRISTOPHER F , ELLEN LAIRD , LI REN , ROBINSON JOHN E , BURGESS LAURENCE E , MORENO DAVID A , SCHLACTER STEVEN T
IPC: C07D401/14 , A61K31/505 , A61K31/519 , A61P7/00 , A61P29/00 , A61P35/00 , A61P37/00
Abstract: Compuestos de Fórmula I, y estereoisómeros y sales y solvatos farmacéuticamente aceptables de estos, donde R1, R2, R3, R4, R5, R6, X1 y X2 tienen los significados que se proporcionan en la memoria descriptiva, son inhibidores de una o más cinasas JAK y son útiles en el tratamiento de enfermedades autoinmunitarias, enfermedades inflamatorias, rechazo de órganos, tejidos y células transplantadas, así como neoplasias y trastornos hematológicos y sus comorbilidades.
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公开(公告)号：UA109131C2
公开(公告)日：2015-07-27
申请号：UAA201212901
申请日：2011-04-11
Applicant: ARRAY BIOPHARMA INC
Inventor： BOYS MARK LAURENCE , BURGESS LAURENCE E , GRONEBERG ROBERT D , HARVEY DARREN M , HUANG LILY , KERCHER TIMOTHY , KRASER CHRISTOPHER F , LAIRD ELLEN , TARLTON EUGENE , ZHAO QIAN
IPC: C07D487/04 , A61K31/519 , A61P29/00 , A61P37/00
Abstract: СоединенияФормулы I: EMBED ISISServer , I иихстереоизомерыи фармацевтическиприемлемыесоли, исольваты, где R1, R2, R3, R4, R5, R6, R7, X1 и X2 имеютзначения, приведенныев описании, являетсяингибиторамиоднойилибольше JAK-кинази пригодныедлялеченияаутоиммунныхзаболеваний, воспалительныхзаболеваний, отторженияпересаженныхорганов, тканейи клеток, атакжегематологическихрасстройстви злокачественныхновообразований, исопутствующихзаболеваний.
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公开(公告)号：AU2015201991A1
公开(公告)日：2015-05-07
申请号：AU2015201991
申请日：2015-04-21
Applicant: ARRAY BIOPHARMA INC
Inventor： BOYS MARK LAURENCE , BURGESS LAURENCE E , GRONEBERG ROBERT D , HARVEY DARREN M , HUANG LILY , KERCHER TIMOTHY , KRASER CHRISTOPHER F , LAIRD ELLEN , TARLTON EUGENE , ZHAO QIAN
IPC: C07D487/04 , A61K31/519 , A61P29/00 , A61P37/00
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公开(公告)号：MX2012011941A
公开(公告)日：2013-08-27
申请号：MX2012011941
申请日：2011-04-11
Applicant: ARRAY BIOPHARMA INC
Inventor： ZHAO QIAN , GRONEBERG ROBERT D , BOYS MARK LAURENCE , BURGESS LAURENCE E , HUANG LILY , KERCHER TIMOTHY , HARVEY DARREN M , KRASER CHRISTOPHER F , LAIRD ELLEN , TARLTON EUGENE
IPC: C07D487/04 , A61K31/519 , A61P29/00 , A61P37/00
Abstract: Los compuestos de la Fórmula I: y estereoisómeros y sales y solvatos de los mismos farmacéuticamente aceptables en los cuales R1, R2, R3, R4, R5, R6, R7, X1 y X2 tienen los significados dados en la especificación, son inhibidores de una o más JAK cinasas y son útiles en el tratamiento de enfermedades autoinmunitarias, enfermedades inflamatorias, rechazo de órganos, tejidos y células trasplantados, así como también trastornos hematológicos y malignidades y sus co-morbilidades.
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Patent Agency Ranking
公开(公告)号：EP2375899A4
公开(公告)日：2012-06-06
申请号：EP10729483
申请日：2010-01-07
Applicant: ARRAY BIOPHARMA INC
Inventor： RODRIGUEZ MARTHA E , MARESKA DAVID A , HANS JEREMY J , HARVEY DARREN M , GRONEBERG ROBERT D , O'SULLIVAN MICHAEL
IPC: A61K31/445 , A61P3/10 , A61P9/10 , C07D401/12 , C07D401/14 , C07D409/06 , C07D409/14 , C07D413/06 , C07D413/14 , C07D417/14 , C07D471/04
CPC classification number: C07D413/14 , A61K31/445 , C07D401/12 , C07D401/14 , C07D409/06 , C07D409/14 , C07D413/06 , C07D417/14 , C07D471/04
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公开(公告)号：AU2011240808B2
公开(公告)日：2015-01-22
申请号：AU2011240808
申请日：2011-04-11
Applicant: ARRAY BIOPHARMA INC
Inventor： BOYS MARK LAURENCE , BURGESS LAURENCE E , GRONEBERG ROBERT D , HARVEY DARREN M , HUANG LILY , KERCHER TIMOTHY , KRASER CHRISTOPHER F , LAIRD ELLEN , TARLTON EUGENE , ZHAO QIAN
IPC: C07D487/04 , A61K31/519 , A61P29/00 , A61P37/00
Abstract: Compounds of Formula I: (Formula should be inserted here) and stereoisomers and pharmaceutically acceptable salts and solvates thereof in which R
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公开(公告)号：CR20120572A
公开(公告)日：2013-02-20
申请号：CR20120572
申请日：2012-11-09
Applicant: ARRAY BIOPHARMA INC
Inventor： BOYS MARK LAURENCE , BURGESS LAURENCE E , GRONEBERG ROBERT D , HARVEY DARREN M , HUANG LILY , KERCHER TIMOTHY , KRASER CHRISTOPHER F , LAIRD ELLEN , TARLTON EUGENE , ZHAO QIAN
IPC: C07D487/04 , A61K31/519 , A61P29/00 , A61P37/00
Abstract: Los compuestos de la Fórmula I y estereoisómeros y sales y solvatos de los mismos farmacéuticamente aceptables en los cuales R1, R2, R3, R4, R5, R6, R7, X1 y X2 tienen los significados dados en la especificación, son inhibidores de una o más cinasas JAK y son útiles en el tratamiento de enfermedades autoinmunitarias, enfermedades inflamatorias, rechazo de órganos, tejidos y células transplantados, así como también trastornos hematológicos y malignidades y sus co-morbilidades.
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公开(公告)号：SG184870A1
公开(公告)日：2012-11-29
申请号：SG2012076493
申请日：2011-04-11
Applicant: ARRAY BIOPHARMA INC
Inventor： BOYS MARK LAURENCE , BURGESS LAURENCE E , GRONEBERG ROBERT D , HARVEY DARREN M , HUANG LILY , KERCHER TIMOTHY , KRASER CHRISTOPHER F , LAIRD ELLEN , TARLTON EUGENE , ZHAO QIAN
Abstract: Compounds of Formula I: (Formula should be inserted here) and stereoisomers and pharmaceutically acceptable salts and solvates thereof in which R1, R2, R3, R4, R5, R6, R7, X1 and X2 have the meanings given in the specification, are inhibitors of one or more JAK kinases and are useful in the treatment of autoimmune diseases, inflammatory diseases, rejection of transplanted organs, tissues and cells, as well as hematologic disorders and malignancies and their co-morbidities.
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公开(公告)号：CA2796388A1
公开(公告)日：2011-10-20
申请号：CA2796388
申请日：2011-04-11
Applicant: ARRAY BIOPHARMA INC
Inventor： BOYS MARK LAURENCE , BURGESS LAURENCE E , GRONEBERG ROBERT D , HARVEY DARREN M , HUANG LILY , KERCHER TIMOTHY , KRASER CHRISTOPHER F , LAIRD ELLEN , TARLTON EUGENE , ZHAO QIAN
IPC: C07D487/04 , A61K31/519 , A61P29/00 , A61P37/00
Abstract: Compounds of Formula I: (Formula should be inserted here) and stereoisomers and pharmaceutically acceptable salts and solvates thereof in which R1, R2, R3, R4, R5, R6, R7, X1 and X2 have the meanings given in the specification, are inhibitors of one or more JAK kinases and are useful in the treatment of autoimmune diseases, inflammatory diseases, rejection of transplanted organs, tissues and cells, as well as hematologic disorders and malignancies and their co-morbidities.
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