Abstract:
PROBLEM TO BE SOLVED: To provide a method, apparatus, and system for separating blood and other types of cellular components.SOLUTION: One of the exemplary methods includes: providing a first flow having a plurality of blood components; providing a second flow; contacting the first flow with the second flow to provide a first separation region; and differentially sedimenting a first blood cellular component of the plurality of blood components into the second flow while concurrently maintaining a second blood cellular component of the plurality of blood components in the first flow. The second flow having the first blood cellular component is then differentially removed from the first flow having the second blood cellular component. Holographic optical traps 200 may also be utilized in conjunction with the various flows to move selected components from one flow to another, as part of or in addition to a separation stage.
Abstract:
PROBLEM TO BE SOLVED: To provide a method, apparatus and system for separation of particulate or cellular materials such as blood and semen and other particles or cells, using multiple laminar flows which further may be coupled with laser steering such as holographic optical trapping and manipulation.SOLUTION: The methods includes: providing a first flow having a plurality of blood components and a second flow; contacting the first flow with the second flow to provide a first separation region; and differentially sedimenting a first blood cellular component of the plurality of blood components into the second flow while concurrently maintaining a second blood cellular component of the plurality of blood components in the first flow. The second flow having the first blood cellular component is then differentially removed from the first flow having the second blood cellular component. Holographic optical traps may also be utilized in conjunction with the various flows to move selected components from one flow to another, as part of or in addition to a separation stage.
Abstract:
PROBLEM TO BE SOLVED: To provide a method, apparatus and system for separating blood and other types of cellular components, and which can be combined with holographic optical trapping manipulation or other forms of optical tweezing. SOLUTION: One of the exemplary methods includes: providing a first flow having a plurality of blood components; providing a second flow; contacting the first flow with the second flow to provide a first separation region; and differentially sedimenting a first blood cellular component of the plurality of blood components into the second flow while concurrently maintaining a second blood cellular component of the plurality of blood components in the first flow. The second flow having the first blood cellular component is then differentially removed from the first flow having the second blood cellular component. COPYRIGHT: (C)2011,JPO&INPIT
Abstract:
An apparatus (100) for separating a plurality of components (A, B, C, E) in a fluid includes an optically transparent sorting channel (110) having a first inlet (120) for a first flow (W) and a second inlet (120) for a second flow (X), and a first outlet (130) for the first flow (W) and a second outlet (130) for the second flow (X); and a holographic optical trap system (210) coupled to the optically transparent sorting channel (200) for selectively moving a first component (A) of the plurality of components (A, B, C, E) in the first flow (W) into the second flow (X) to form an enriched second flow (X).
Abstract:
An apparatus (100) for separating a plurality of components (A, B, C, E) in a fluid includes an optically transparent sorting channel (110) having a first inlet (120) for a first flow (W) and a second inlet (120) for a second flow (X), and a first outlet (130) for the first flow (W) and a second outlet (130) for the second flow (X); and a holographic optical trap system (210) coupled to the optically transparent sorting channel (200) for selectively moving a first component (A) of the plurality of components (A, B, C, E) in the first flow (W) into the second flow (X) to form an enriched second flow (X).