公开(公告)号：WO2016024286A2

公开(公告)日：2016-02-18

申请号：PCT/IN2015/000318

申请日：2015-08-11

Applicant: AVRA LABORATORIES PVT. LTD.

Inventor： RAO, Ramakrishna ,  NANDIPATI, Ramadevi ,  GOODA, Ravi ,  SHEWALKAR, Mukesh, Padmakar ,  BHADKE, Venkat, Vasantrao

CPC classification number: C07D401/04

Abstract: Disclosed herein is an improved process for preparation of Lenalidomide and crystalline polymorphic forms thereof.

Abstract translation: 本文公开了一种改进的来那度胺及其结晶多晶型的制备方法。

公开(公告)号：WO2022144924A1

公开(公告)日：2022-07-07

申请号：PCT/IN2021/051218

申请日：2021-12-30

Applicant: AVRA LABORATORIES PVT. LTD.

Inventor： RAO, Ramakrishna ,  SHEWALKAR, Mukesh Padmakar

IPC: A61K31/454 ,  C07D401/04 ,  C07D209/46

Abstract: The present invention discloses an improved process for preparation of Lenalidomide and crystalline polymorphic forms thereof. More particularly, the invention relates to preparation of Lenalidomide with high yields and purity and to preparation of crystalline polymorphic form A and Form B.

公开(公告)号：WO2017072790A1

公开(公告)日：2017-05-04

申请号：PCT/IN2016/050362

申请日：2016-10-26

Applicant: AVRA LABORATORIES PVT. LTD.

Inventor： RAO, Ramakrishna ,  NANDIPATI, Ramadevi ,  SHEWALKAR, Mukesh Padmakar ,  BOGIREDDY, Veerabhadra Reddy

IPC: A61K31/519 ,  C07D405/12 ,  C07D487/04

CPC classification number: C07D487/04

Abstract: The present invention discloses an improved and cost effective process for preparation of Ticagrelor in good yield and purity. The invention further discloses novel Polymorphic Form of Ticagrelor and its process for preparation thereof.

Abstract translation: 本发明公开了一种以良好收率和纯度制备替格瑞洛的改进的和成本有效的方法。 本发明进一步公开了替格瑞洛的新型多晶型物及其制备方法。

公开(公告)号：WO2012032531A1

公开(公告)日：2012-03-15

申请号：PCT/IN2010/000754

申请日：2010-11-19

Applicant: AVRA LABORATORIES PVT. LTD. ,  ALLA, Venkata, Rama, Rao ,  RAO, Ramakrishna ,  RAMARAO, Chandrashekar ,  NANDIPATI, Ramadevi ,  CHAMLE, Vinay, Avinash

Inventor： ALLA, Venkata, Rama, Rao ,  RAO, Ramakrishna ,  RAMARAO, Chandrashekar ,  NANDIPATI, Ramadevi ,  CHAMLE, Vinay, Avinash

IPC: A01N43/42

CPC classification number: C07D491/22

Abstract: Disclosed herein is a highly safe and easily scalable process for the production of 7-Ethyl- 10-hydroxycamptothecin and its conversion to Irinotecan hydrochloride by total synthesis.

Abstract translation: 本文公开了一种用于生产7-乙基-10-羟基喜树碱及其通过全合成转化为盐酸伊立替康的高度安全且易于扩展的方法。

公开(公告)号：WO2011064790A1

公开(公告)日：2011-06-03

申请号：PCT/IN2010/000086

申请日：2010-02-15

Applicant: AVRA LABORATORIES PVT. LTD ,  RAMARAO, Chandrashekar ,  MICHEL, Patrick, Thomas ,  NAVAKOTI, Rajasekhar ,  NANDIPATI, Rama, Devi ,  RAO, Ramakrishna

Inventor： RAMARAO, Chandrashekar ,  MICHEL, Patrick, Thomas ,  NAVAKOTI, Rajasekhar ,  NANDIPATI, Rama, Devi ,  RAO, Ramakrishna

IPC: C07C237/22 ,  C07C231/14 ,  C07D317/10 ,  C07D317/20 ,  C07D317/26

CPC classification number: C07C237/22 ,  C07C271/22 ,  C07D207/08 ,  C07D307/33 ,  C07D307/58 ,  C07D317/20 ,  C07D317/26 ,  C07D405/04

Abstract: A novel process for making Renin inhibitors like Aliskiren is disclosed. Its novel intermediate compounds and method of making them are also disclosed.

Abstract translation: 公开了一种制造肾素抑制剂如阿利吉仑的新方法。 还公开了其新型中间体化合物及其制备方法。