公开(公告)号：WO2004046707A1

公开(公告)日：2004-06-03

申请号：PCT/US2003/036770

申请日：2003-11-18

Applicant: ADVANCED SENSOR TECHNOLOGIES ,  CANTOR, Hal, C. ,  HOWER, Robert, W.

Inventor： CANTOR, Hal, C. ,  HOWER, Robert, W.

IPC: G01N27/327

CPC classification number: G01N33/4836

Abstract: On-chip closed loop control circuitry comprising an amperometric sensing system, a potentiometric sensing system, at least one differentiator connected to said amperometric and potentiometric sensing systems, at least one integrator connected to said amperometric and potentiometric sensing systems, and noise reduction means. A recording device and chip for measuring neurochemical and neuroelectrical activity in tissue culture having at least one potentiometric electrode, at least one amperometric electrode interconnected to the potentiometric electrode, wherein the electrodes are located on the same device, and circuitry for eliminating frequency noise. Also provided is software for controlling the chip.

Abstract translation: 片上闭环控制电路，包括电流检测系统，电位传感系统，连接到所述电流分析和电位传感系统的至少一个微分器，连接到所述电流和电位传感系统的至少一个积分器，以及降噪装置。 一种用于测量组织培养物中的神经化学和神经电活性的记录装置和芯片，其具有至少一个电位电极，至少一个与电位电极互连的电流电极，其中电极位于相同的装置上，以及用于消除频率噪声的电路。 还提供了用于控制芯片的软件。

公开(公告)号：WO2004023105A2

公开(公告)日：2004-03-18

申请号：PCT/US2003/008575

申请日：2003-03-20

Applicant: ADVANCED SENSOR TECHNOLOGIES, INC. ,  CANTOR, Hal, C. ,  HOWER, Robert, W. ,  COSMIN, Lucian

Inventor： CANTOR, Hal, C. ,  HOWER, Robert, W. ,  COSMIN, Lucian

IPC: G01N

CPC classification number: B01L3/502738 ,  B01L3/502707 ,  B01L3/50273 ,  B01L3/502746 ,  B01L2200/10 ,  B01L2200/12 ,  B01L2300/024 ,  B01L2300/025 ,  B01L2300/0636 ,  B01L2300/0645 ,  B01L2300/0816 ,  B01L2400/0406 ,  B01L2400/0442 ,  B01L2400/0481 ,  B01L2400/0487 ,  B01L2400/0633 ,  B01L2400/0638 ,  B01L2400/0677 ,  B01L2400/086 ,  G01N2201/04

Abstract: A micro-device for testing for agents in a fluid including at least one micro-chamber and a sensor for sensing agents in the fluid, the sensor is located within the micro-chamber. A micro-device for testing for agents in a fluid including a micro-chamber and a micro-fluidic system, the micro-fluidic system is used for pumping the fluid into the micro-chamber. A micro-device for testing for agents in a fluid including a miniature micro-chamber for testing for agents in a small amount of fluid.

Abstract translation: 一种用于测试流体中的试剂的微型装置，包括至少一个微室和用于感测流体中的试剂的传感器，传感器位于微室内。 用于在包括微室和微流体系统的流体中测试试剂的微型装置，微流体系统用于将流体泵送到微室中。 用于测试流体中的试剂的微型装置，包括用于测试少量流体中的试剂的微型微室。

公开(公告)号：EP1226425A1

公开(公告)日：2002-07-31

申请号：EP00976858.1

申请日：2000-11-02

Applicant: Advanced Sensor Technologies, Inc.

Inventor： CANTOR, Hal, C. ,  STRONG, Timothy, D. ,  BROWN, Richard, B. ,  HOWER, Robert, W.

IPC: G01N27/26

CPC classification number: G01N27/3277

Abstract: According to the present invention, there is provided an electronic device for monitoring active biological operations including a support substrate, at least one amperometric sensor, and at least one potentiometric sensor.

公开(公告)号：EP1317625A1

公开(公告)日：2003-06-11

申请号：EP01968418.2

申请日：2001-08-31

Applicant: Advanced Sensor Technologies

Inventor： HOWER, Robert, W. ,  CANTOR, Hal, C. ,  MONDRO, Jason, R.

IPC: F04B35/02 ,  F16K31/122 ,  F16K7/04

CPC classification number: F04B19/006 ,  A61B5/0002 ,  A61B5/145 ,  A61B5/14514 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1491 ,  A61B2560/0412 ,  B01L3/50273 ,  B01L3/502738 ,  B01L2200/10 ,  B01L2300/0636 ,  B01L2300/0645 ,  B01L2300/0816 ,  B01L2300/087 ,  B01L2400/0442 ,  B01L2400/0481 ,  B01L2400/0655 ,  B01L2400/086 ,  B81B1/00 ,  B81B3/0024 ,  B81B2201/036 ,  B81B2201/054 ,  F04B43/046 ,  F15B2015/208 ,  F16K99/0001 ,  F16K99/0015 ,  F16K99/0036 ,  F16K99/0061 ,  F16K2099/0069 ,  F16K2099/0074 ,  F16K2099/0076 ,  F16K2099/008 ,  F16K2099/0084

Abstract: According to the present invention, there is provided a micro-fluidic sensor system (6) including a micro-conduit (56) for carrying fluid therethrough having a flexible wall portion (18), at least one micro-fluidic actuator having a closed cavity, flexible mechanism defining a wall of the cavity (11) and flexible wall portion (18) of the micro-conduit for deflecting upon an application of pressure thereto, and expanding mechanism (14) disposed in the cavity for selectively expanding the cavity and thereby selectively flexing said expanding mechanism, and sensor mechanism in fluid communication with the micro-conduit for sensing the presence or absence of molecules. The present invention further provides for a micro-fluidic system for moving micro-fluid amounts including a micro-conduit and at least one micro-fluidic actuator in fluid communication with the micro-conduit.