公开(公告)号：JPH0477732B2

公开(公告)日：1992-12-09

申请号：JP17688784

申请日：1984-08-27

Applicant: BASF AG

Inventor： DEIITAA HERU

IPC: C08B37/10 ,  A61K9/48 ,  A61K31/715 ,  A61K45/08 ,  A61K47/10 ,  A61K47/14 ,  A61K47/26 ,  A61P7/02

公开(公告)号：JPH01230519A

公开(公告)日：1989-09-14

申请号：JP32485288

申请日：1988-12-24

Applicant: BASF AG

Inventor： DEIITAA HERU ,  TOOMASU DERUPAA ,  ROOTAA DAUMU ,  KAARUUHAINTSU GAISU ,  AKIMU MERAA

IPC: C08B37/10 ,  A61K20060101 ,  A61K31/715 ,  A61P31/12

Abstract: PURPOSE: To obtain a medicine for preventing and treating diseases caused by retroviruses by using polysulfated heparin. CONSTITUTION: Polysulfated heparin having a sulfur content of 13-15% or its salt as an active ingredient, a known preparation carrier, a known excipient, etc., are compounded and subsequently prepared into the objective preparation by a conventional method. The preparation may be prepared in the form of tablets, capsules, powder, granules, injection agents, sprays, etc. The active ingredient is administered orally at a dose of 10-1000mg/Kg or parenterally at a dose of 0.1-10mg/Kg. The polysulfated heparin is obtained by converting heparin into the corresponding pyridinium salt and subsequently polysulfating the pyridinium salt with chlorosulfonic acid in pyridine.

公开(公告)号：JPS60155138A

公开(公告)日：1985-08-15

申请号：JP17688784

申请日：1984-08-27

Applicant: BASF AG

Inventor： DEIITAA HERU

IPC: C08B37/10 ,  A61K9/48 ,  A61K31/715 ,  A61K45/08 ,  A61K47/10 ,  A61K47/14 ,  A61K47/26 ,  A61P7/02