公开(公告)号：HU220875B1

公开(公告)日：2002-06-29

申请号：HU9603067

申请日：1995-04-26

Applicant: BASF AG

Inventor： DR AMBERG WILHELM ,  DR BERNARD HARALD ,  DR BUSCHMANN ERNST ,  DR DE POTZOLLI BERND ,  DR HAUPT ANDREAS ,  DR JANITSCHKE LOTHAR ,  DR JANSSEN BERND ,  DR KARL ULRICH ,  DR KLING ANDREAS ,  DR MUELLER STEFAN ,  DR RITTER KURT ,  DR THYES MARCO ,  DR ZIERKE THOMAS

IPC: A61K38/08 ,  A61K38/00 ,  A61P35/00 ,  C07K1/08 ,  C07K5/10 ,  C07K5/103 ,  C07K7/06 ,  C07K14/52

Abstract: PCT No. PCT/EP95/01577 Sec. 371 Date Nov. 4, 1996 Sec. 102(e) Date Nov. 4, 1996 PCT Filed Apr. 26, 1995 PCT Pub. No. WO95/30691 PCT Pub. Date Nov. 16, 1995The compound Me2Val-Val-MeVal-Pro-Pro-NHBzlxHCl is described. It is prepared from Z-Val-Val-MeVal-Pro-OR1 where Z and R1 have the meanings stated in the description. The compound shows antineoplastic activity.

公开(公告)号：HU220862B1

公开(公告)日：2002-06-29

申请号：HU9603068

申请日：1995-04-26

Applicant: BASF AG

Inventor： DR AMBERG WILHELM ,  DR BERNARD HARALD ,  DR BUSCHMANN ERNST ,  DR DE POTZOLLI BERND ,  DR HAUPT ANDREAS ,  DR JANITSCHKE LOTHAR ,  DR JANSSEN BERND ,  DR KARL ULRICH ,  DR KLING ANDREAS ,  DR MUELLER STEFAN ,  DR RITTER KURT ,  DR THYES MARCO ,  DR ZIERKE THOMAS

IPC: A61K38/00 ,  A61P35/00 ,  C07K5/10 ,  C07K5/103 ,  C07K7/06

Abstract: Compounds of the formulawhere R1, R2, R3 and R4 have the meaning stated in the description, and a process for preparing them are described. The compounds are suitable as starting material for synthesizing substances which are active against tumors.