公开(公告)号：DE4425144A1

公开(公告)日：1996-01-18

申请号：DE4425144

申请日：1994-07-15

Applicant: BASF AG

Inventor： HELLENDAHL BEATE DR ,  LANSKY ANNEGRET DR ,  MUNSCHAUER RAINER DR ,  BIALOJAN SIEGFRIED DR ,  UNGER LILIANE DR ,  TESCHENDORF HANS-JUERGEN DR ME ,  WICKE CARSTEN DR ,  DRESCHER KARLA DR

IPC: C07D249/08 ,  A61K31/41 ,  A61K31/435 ,  A61K31/4427 ,  A61K31/445 ,  A61K31/505 ,  A61K31/53 ,  A61P1/08 ,  A61P25/18 ,  A61P25/20 ,  A61P25/24 ,  A61P25/26 ,  C07D249/12 ,  C07D249/14 ,  C07D401/06 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D403/14

Abstract: The present invention relates to triazole compounds of formula (I) in which R , R stand for H or different substituents, A stands for a bivalent group, B stands for a rest of the formula (a), (b) or (c) and Ar stands for optionally substituted phenyl, pyridyl, pyrimidyl or triazinyl. The compounds of the invention have a high affinity for the dopamine-D3-receptor and are therefore usable for the treatment of diseases responding to dopamine-D3-ligands.

公开(公告)号：CZ9797A3

公开(公告)日：1997-08-13

申请号：CZ9797

申请日：1995-07-14

Applicant: BASF AG

Inventor： HELLENDAHL BEATE DR ,  LANSKY ANNEGRET DR ,  MUNSCHAUER RAINER DR ,  BIALOJAN SIEGFRIED DR ,  UNGER LILIANE DR ,  TESCHENDORF HANS-JURGEN DR ,  WICKE KARSTEN DR ,  DRESCHER KARLA DR

IPC: C07D249/08 ,  A61K31/41 ,  A61K31/435 ,  A61K31/4427 ,  A61K31/445 ,  A61K31/505 ,  A61K31/53 ,  A61P1/08 ,  A61P25/18 ,  A61P25/20 ,  A61P25/24 ,  A61P25/26 ,  C07D249/12 ,  C07D249/14 ,  C07D401/06 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D403/14

Abstract: PCT No. PCT/EP95/02781 Sec. 371 Date Jan. 14, 1997 Sec. 102(e) Date Jan. 14, 1997 PCT Filed Jul. 14, 1995 PCT Pub. No. WO96/02520 PCT Pub. Date Feb. 1, 1996The present invention relates to triazole compounds of the following formula: where R1, R2, A, B and Ar have the meanings stated in the description. The compounds according to the invention have a high affinity for the dopamine D3 receptor and can therefore be used to treat disorders which respond to dopamine D3 ligands.

公开(公告)号：CZ9700097A3

公开(公告)日：1997-08-13

申请号：CZ9797

申请日：1995-07-14

Applicant: BASF AG

Inventor： HELLENDAHL BEATE DR ,  LANSKY ANNEGRET DR ,  MUNSCHAUER RAINER DR ,  BIALOJAN SIEGFRIED DR ,  UNGER LILIANE DR ,  TESCHENDORF HANS-JURGEN DR ,  WICKE KARSTEN DR ,  DRESCHER KARLA DR

IPC: C07D249/08 ,  A61K31/41 ,  A61K31/435 ,  A61K31/4427 ,  A61K31/445 ,  A61K31/505 ,  A61K31/53 ,  A61P1/08 ,  A61P25/18 ,  A61P25/20 ,  A61P25/24 ,  A61P25/26 ,  C07D249/12 ,  C07D249/14 ,  C07D401/06 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D403/14

CPC classification number: C07D403/12 ,  C07D249/12