公开(公告)号：DE69918163D1

公开(公告)日：2004-07-22

申请号：DE69918163

申请日：1999-12-14

Applicant: BASF AG

Inventor： EINIG HEINZ ,  HACH HARALD ,  THOMPSON C ,  EASON RAYMOND ,  MUELLER W

IPC: A61K9/20 ,  A61K9/28 ,  A61K9/36 ,  A61K31/19 ,  A61K31/192 ,  A61P29/00

Abstract: A pharmaceutical mixture comprising a profen is described which has a profen content of over 85 % and contains up to 1% of a nonionic surfactant having an HLB of >/=9 and also a customary disintegrant and a lubricant and optionally a microcrystalline cellulose.

公开(公告)号：NO20013499A

公开(公告)日：2001-09-10

申请号：NO20013499

申请日：2001-07-13

Applicant: BASF AG

Inventor： EINIG HEINZ ,  HACH HARALD ,  EASON RAYMOND ,  MUELLER BERND WILLI WERNER ,  THOMPSON RICHARD C

IPC: A61K9/20 ,  A61K31/19 ,  A61K31/192 ,  A61K31/485 ,  A61K31/52 ,  A61K45/00 ,  A61K47/14 ,  A61K47/30 ,  A61K47/36 ,  A61K47/38 ,  A61P27/16 ,  A61P29/00

CPC classification number: A61K31/19 ,  A61K9/2013 ,  A61K31/485 ,  A61K31/52 ,  A61K2300/00

公开(公告)号：CA2360227A1

公开(公告)日：2000-07-20

申请号：CA2360227

申请日：2000-01-07

Applicant: BASF AG

Inventor： EASON RAYMOND ,  THOMPSON RICHARD C ,  MULLER BERND W ,  HACH HARALD ,  EINIG HEINZ

IPC: A61K9/20 ,  A61K31/19 ,  A61K31/192 ,  A61K31/485 ,  A61K31/52 ,  A61K45/00 ,  A61K47/14 ,  A61K47/30 ,  A61K47/36 ,  A61K47/38 ,  A61P27/16 ,  A61P29/00 ,  A61K31/137 ,  A61K31/522

Abstract: A pharmaceutical mixture comprising a profen and one or more additional acti ve compounds is described which has a total active compound content of over 85 % and contains up to 1 %, based on the content of the profen, of a nonionic surfactant having an HLB of >= 9 and a customary disintegrant and a lubri cant.

公开(公告)号：CZ298604B6

公开(公告)日：2007-11-21

申请号：CZ20012228

申请日：1999-12-14

Applicant: BASF AG

Inventor： EINIG HEINZ ,  HACH HARALD ,  THOMPSON RICHARD C ,  EASON RAYMOND ,  MUELLER BERND W

IPC: A61K31/192 ,  A61K9/20 ,  A61K9/28 ,  A61K9/36 ,  A61K31/19 ,  A61P29/00

Abstract: Farmaceutická smes v pevné forme vhodné pro tabletování a obsahující profen v množství více než 85 % hmotnostních profenu a až 1 % hmotnostní neiontové povrchove aktivní látky s HLB .>=. 9, vztaženo na celkovou hmotnost smesi, a dále bežné dezintegracní cinidlo a bežný lubrikant. Uvedeným profenem je výhodne ibuprofen nebo flurbiprofen.

公开(公告)号：DE60009652T2

公开(公告)日：2005-03-24

申请号：DE60009652

申请日：2000-01-07

Applicant: BASF AG

Inventor： EINIG HEINZ ,  HACH HARALD ,  EASON RAYMOND ,  MUELLER W ,  THOMPSON C

IPC: A61K9/20 ,  A61K31/19 ,  A61K31/192 ,  A61K31/485 ,  A61K31/52 ,  A61K45/00 ,  A61K47/14 ,  A61K47/30 ,  A61K47/36 ,  A61K47/38 ,  A61P27/16 ,  A61P29/00 ,  A61K31/522

Abstract: A pharmaceutical mixture comprising a profen and one or more additional active compounds is described which has a total active compound content of over 85% and contains up to 1%, based on the content of the profen, of a nonionic surfactant having an HLB of >=9 and a customary disintegrant and a lubricant.

公开(公告)号：ES2224743T3

公开(公告)日：2005-03-01

申请号：ES99967936

申请日：1999-12-14

Applicant: BASF AG

Inventor： EINIG HEINZ ,  HACH HARALD ,  THOMPSON RICHARD C ,  EASON RAYMOND ,  MILLER BERND W

IPC: A61K9/20 ,  A61K9/28 ,  A61K9/36 ,  A61K31/19 ,  A61K31/192 ,  A61P29/00

Abstract: Una mezcla farmacéutica para la obtención directa de comprimidos de un profeno, que tiene un contenido en profeno mayor del 85% y contiene hasta 1% de un surfactante no iónico que tiene un HLB de 9% y también un desintegrante usual y un lubricante y en donde los componentes se han mezclado en una forma en seco.

公开(公告)号：AT269059T

公开(公告)日：2004-07-15

申请号：AT99967936

申请日：1999-12-14

Applicant: BASF AG

Inventor： EINIG HEINZ ,  HACH HARALD ,  THOMPSON RICHARD C ,  EASON RAYMOND ,  MUELLER BERND W

IPC: A61K9/20 ,  A61K9/28 ,  A61K9/36 ,  A61K31/19 ,  A61K31/192 ,  A61P29/00

Abstract: A pharmaceutical mixture comprising a profen is described which has a profen content of over 85 % and contains up to 1% of a nonionic surfactant having an HLB of >/=9 and also a customary disintegrant and a lubricant and optionally a microcrystalline cellulose.

公开(公告)号：MXPA01006791A

公开(公告)日：2003-07-14

申请号：MXPA01006791

申请日：2000-01-07

Applicant: BASF AG

Inventor： EASON RAYMOND

IPC: A61K9/20 ,  A61K31/19 ,  A61K31/192 ,  A61K31/485 ,  A61K31/52 ,  A61K45/00 ,  A61K47/14 ,  A61K47/30 ,  A61K47/36 ,  A61K47/38 ,  A61P27/16 ,  A61P29/00 ,  A61K31/137 ,  A61K31/522

公开(公告)号：DK1128820T3

公开(公告)日：2004-08-09

申请号：DK00912425

申请日：2000-01-07

Applicant: BASF AG

Inventor： EINIG HEINZ ,  HACH HARALD ,  EASON RAYMOND ,  MUELLER BERND W ,  THOMPSON RICHARD C

IPC: A61K9/20 ,  A61K31/19 ,  A61K31/192 ,  A61K31/485 ,  A61K31/52 ,  A61K45/00 ,  A61K47/14 ,  A61K47/30 ,  A61K47/36 ,  A61K47/38 ,  A61P27/16 ,  A61P29/00 ,  A61K31/522

Abstract: A pharmaceutical mixture comprising a profen and one or more additional active compounds is described which has a total active compound content of over 85% and contains up to 1%, based on the content of the profen, of a nonionic surfactant having an HLB of >=9 and a customary disintegrant and a lubricant.

公开(公告)号：AT263547T

公开(公告)日：2004-04-15

申请号：AT00912425

申请日：2000-01-07

Applicant: BASF AG

Inventor： EINIG HEINZ ,  HACH HARALD ,  EASON RAYMOND ,  MUELLER BERND W ,  THOMPSON RICHARD C

IPC: A61K9/20 ,  A61K31/19 ,  A61K31/192 ,  A61K31/485 ,  A61K31/52 ,  A61K45/00 ,  A61K47/14 ,  A61K47/30 ,  A61K47/36 ,  A61K47/38 ,  A61P27/16 ,  A61P29/00 ,  A61K31/522 ,  A61K31/137

Abstract: A pharmaceutical mixture comprising a profen and one or more additional active compounds is described which has a total active compound content of over 85% and contains up to 1%, based on the content of the profen, of a nonionic surfactant having an HLB of >=9 and a customary disintegrant and a lubricant.