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公开(公告)号：HU0402006A2
公开(公告)日：2005-01-28
申请号：HU0402006
申请日：2002-10-25
Applicant: BASF AG
Inventor： EINIG HEINZ , MUELLER BERND W , RASENACK NORBERT , FRIESE KATRIN , FRANKE DIRK
IPC: A61K9/20 , A61K9/14 , A61K9/16 , A61K9/26 , A61K31/192 , A61P29/00 , C07C51/43 , C07C51/50 , C07C57/30 , C07C59/64
Abstract: The present invention relates to a process for the formation of profen crystals, which comprises carrying out the formation of solids by displacement precipitation, cooling crystallization, evaporative crystallization or a combination thereof in the presence of one or more additives, and the use of the profens thus prepared for pharmaceutical formulations.
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公开(公告)号：DE10153934A1
公开(公告)日：2003-05-22
申请号：DE10153934
申请日：2001-11-06
Applicant: BASF AG
Inventor： EINIG HEINZ , MUELLER BERND W , RASENACK NORBERT
IPC: A61K9/20 , A61K9/14 , A61K9/16 , A61K9/26 , A61K31/192 , A61P29/00 , C07C51/43 , C07C51/50 , C07C57/30 , C07C59/64 , C07C51/41 , C07B63/00 , C30B28/04
Abstract: The invention relates to a method for the formation of ibuprofen crystals, characterised in that the solidification occurs after crystallisation by displacement, crystallisation by cooling, crystallisation by evaporation or a combination thereof in the presence of one or several additives and the use of the ibuprofen produced as above for pharmaceutical formulations.
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公开(公告)号：ZA200106625B
公开(公告)日：2002-08-13
申请号：ZA200106625
申请日：2001-08-13
Applicant: BASF AG
Inventor： EINIG HEINZ , HACH HARALD , EASON RAYMOND , MUELLER BERND W , THOMPSON RICHARD C
IPC: A61K9/20 , A61K31/19 , A61K31/192 , A61K31/485 , A61K31/52 , A61K45/00 , A61K47/14 , A61K47/30 , A61K47/36 , A61K47/38 , A61P27/16 , A61P29/00 , A61K
Abstract: A pharmaceutical mixture comprising a profen and one or more additional active compounds is described which has a total active compound content of over 85% and contains up to 1%, based on the content of the profen, of a nonionic surfactant having an HLB of >=9 and a customary disintegrant and a lubricant.
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公开(公告)号：BR0007503A
公开(公告)日：2002-01-08
申请号：BR0007503
申请日：2000-01-07
Applicant: BASF AG
Inventor： EINIG HEINZ , HACH HARALD , EASON RAYMOND , MUELLER BERND W , THOMPSON RICHARD C
IPC: A61K9/20 , A61K31/19 , A61K31/192 , A61K31/485 , A61K31/52 , A61K45/00 , A61K47/14 , A61K47/30 , A61K47/36 , A61K47/38 , A61P27/16 , A61P29/00 , A61K31/522
Abstract: A pharmaceutical mixture comprising a profen and one or more additional active compounds is described which has a total active compound content of over 85% and contains up to 1%, based on the content of the profen, of a nonionic surfactant having an HLB of >=9 and a customary disintegrant and a lubricant.
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公开(公告)号：ZA200710874B
公开(公告)日：2009-02-25
申请号：ZA200710874
申请日：2007-12-14
Applicant: BASF AG
Inventor： JENS RENNER , JOCHEN DIETZ , MARKUS GEWEHR , THOMAS GROTE , WASSILIOS GRAMMENOS , UDO HUENGER , MUELLER BERND W , FRANK SCHIEWECK , ANJA SCHWOEGLER , KLAAS LOHMANN JAN , JOACHIM RHEINHEIMER , PETER SCHAEFER
IPC: A01N20090101 , C07D20090101
Abstract: Thiazolecarboxanilides of the formula I in which the variables are as defined below: A is X is halogen; Y is cyano, nitro, C1-C4-alkyl, C1-C4-haloalkyl, methoxy or methylthio; p is 0, 1; R1 is hydrogen, halogen, C1-C4-alkyl, C1-C4-haloalkyl; R2 is hydrogen, methyl, halogen; R3 is hydrogen, methyl, ethyl; W is O, S; and processes for preparing these compounds, compositions and seed comprising them and methods for controlling harmful fungi.
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Patent Agency Ranking
公开(公告)号：ZA200105860B
公开(公告)日：2002-07-17
申请号：ZA200105860
申请日：2001-07-17
Applicant: BASF AG
Inventor： EINIG HEINZ , HACH HARALD , THOMPSON RICHARD C , EASON RAYMOND , MUELLER BERND W
Abstract: A pharmaceutical mixture comprising a profen is described which has a profen content of over 85 % and contains up to 1% of a nonionic surfactant having an HLB of >/=9 and also a customary disintegrant and a lubricant and optionally a microcrystalline cellulose.
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公开(公告)号：HU0104606A2
公开(公告)日：2002-05-29
申请号：HU0104606
申请日：1998-12-18
Applicant: BASF AG
Inventor： EASON RAYMOND , EINIG HEINZ , HACH HARALD , MUELLER BERND W , THOMPSON RICHARD C
Abstract: A pharmaceutical mixture comprising a profen is described which has a profen content of over 85 % and contains up to 1% of a nonionic surfactant having an HLB of >/=9 and also a customary disintegrant and a lubricant and optionally a microcrystalline cellulose.
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公开(公告)号：CZ298604B6
公开(公告)日：2007-11-21
申请号：CZ20012228
申请日：1999-12-14
Applicant: BASF AG
Inventor： EINIG HEINZ , HACH HARALD , THOMPSON RICHARD C , EASON RAYMOND , MUELLER BERND W
Abstract: Farmaceutická smes v pevné forme vhodné pro tabletování a obsahující profen v množství více než 85 % hmotnostních profenu a až 1 % hmotnostní neiontové povrchove aktivní látky s HLB .>=. 9, vztaženo na celkovou hmotnost smesi, a dále bežné dezintegracní cinidlo a bežný lubrikant. Uvedeným profenem je výhodne ibuprofen nebo flurbiprofen.
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公开(公告)号：AT269059T
公开(公告)日：2004-07-15
申请号：AT99967936
申请日：1999-12-14
Applicant: BASF AG
Inventor： EINIG HEINZ , HACH HARALD , THOMPSON RICHARD C , EASON RAYMOND , MUELLER BERND W
Abstract: A pharmaceutical mixture comprising a profen is described which has a profen content of over 85 % and contains up to 1% of a nonionic surfactant having an HLB of >/=9 and also a customary disintegrant and a lubricant and optionally a microcrystalline cellulose.
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公开(公告)号：DK1128820T3
公开(公告)日：2004-08-09
申请号：DK00912425
申请日：2000-01-07
Applicant: BASF AG
Inventor： EINIG HEINZ , HACH HARALD , EASON RAYMOND , MUELLER BERND W , THOMPSON RICHARD C
IPC: A61K9/20 , A61K31/19 , A61K31/192 , A61K31/485 , A61K31/52 , A61K45/00 , A61K47/14 , A61K47/30 , A61K47/36 , A61K47/38 , A61P27/16 , A61P29/00 , A61K31/522
Abstract: A pharmaceutical mixture comprising a profen and one or more additional active compounds is described which has a total active compound content of over 85% and contains up to 1%, based on the content of the profen, of a nonionic surfactant having an HLB of >=9 and a customary disintegrant and a lubricant.
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