公开(公告)号：JPH10182493A

公开(公告)日：1998-07-07

申请号：JP35132897

申请日：1997-12-19

Applicant: BASF AG

Inventor： RUNGE FRANK DR ,  ZWISSLER GEORG KONRAD DR ,  END LUTZ DR ,  SCHWEIKERT LONI DR ,  HORN DIETER DR

IPC: A23C9/13 ,  A23C9/152 ,  A23C19/09 ,  A23D7/005 ,  A23D7/01 ,  A23D7/04 ,  A23L2/58 ,  A23L5/44 ,  A61K47/06 ,  C07C403/24 ,  C09B61/00 ,  C09B67/20 ,  A23L1/272

Abstract: PROBLEM TO BE SOLVED: To obtain a stable solubilized carotenoid preparation having particle diameters in the range of 10-200nm, having the concentration of an active compound higher than 0.5wt.% useful for coloring food and medicine preparation. SOLUTION: A suspension containing 1-40wt.% of one or ore carotenoids, 20-90wt.% of one or more nonionic surfactants and 0-50wt.% of another additive is heated to 120-200 deg.C for a short time to give a uniform solution, which is formulated with water or an aqueous solution containing a hydrophilic antioxidant at 10-95 deg.C by turbulent flow with adding another surfactant or not to produce a solubilized carotenoid preparation having 0.5-10wt.% carotenoid content, which is used.

公开(公告)号：JPH1077225A

公开(公告)日：1998-03-24

申请号：JP20161897

申请日：1997-07-28

Applicant: BASF AG

Inventor： WEBER SABINE DR ,  SAMBALE CLEMENS DR ,  END LUTZ DR ,  GAUS GUENTER DR

IPC: A61K9/08 ,  A23L5/44 ,  A23L33/155 ,  A61K9/107 ,  A61K31/015 ,  A61K33/32 ,  A61P3/02 ,  C07C403/24

Abstract: PROBLEM TO BE SOLVED: To obtain an optically transparent aqueous-alcoholic solution of multivitamin containing β-carotene by dissolving the β-carotene in an aqueous- alcoholic solution of the multivitamin so as to be optically transparent. SOLUTION: This optically transparent aqueous-alcoholic soltution of multivitamin containing β-carotene is obtained by mixing a β-carotene emulsion containing >=2wt.% β-carotene based on the emulsion and obtained by dissolving the β-carotene in an oil phase of a dispersed edible oil with optically transparent aqueous alcoholic solution of multivitamin containing vitamins corresponding to 30-300% amount of daily requirement for adult in a daily intake of the solution, and optionally a little amount of minerals. The solution includes 40-150ppm β-carotene.

公开(公告)号：DK0479066T3

公开(公告)日：1995-02-13

申请号：DK91116027

申请日：1991-09-20

Applicant: BASF AG

Inventor： HORN DIETER DR ,  END LUTZ DR ,  LUEDDECKE ERIK DR ,  SCHNEIDER JOACHIM U DR ,  HOPPE PETER PAUL DR ,  RENSMANN FRIEDRICH-WILHELM DR

IPC: A61K9/00 ,  A61K9/107 ,  A61K31/015 ,  A61K9/08 ,  A61K31/07 ,  A61K47/14 ,  A61P15/00 ,  C07B63/04 ,  C07C403/24 ,  C09K23/00

Abstract: Method for the continuous preparation of beta -carotene solubilisates by brief heating of beta -carotene together with an emulsifier until solution takes place, rapid cooling of the homogeneous solution to below 100 DEG C by addition of water and subsequent adjustment of the required final concentrations of beta -carotene, which is characterised in that a suspension, which has been preheated to 20 to 80 DEG C, of 1 to 40% by weight beta -carotene in an emulsifier is pumped through a heating coil located in a heat-transfer oil, where the temperature in the solubilisation mixture is 120 to 180 DEG C and the residence time is 10 to 300 seconds, and the homogeneous solution is turbulently mixed in a mixing chamber with such quantities of water at 10 to 80 DEG C that a solubilisate containing 0.5 to 6% by weight beta -carotene is produced and is, where appropriate, further diluted to the required final concentration.

公开(公告)号：DE19630789A1

公开(公告)日：1998-02-05

申请号：DE19630789

申请日：1996-07-31

Applicant: BASF AG

Inventor： WEBER SABINE DR ,  SAMBALE CLEMENS DR ,  END LUTZ DR ,  GAUS GUENTER DR

IPC: A61K9/08 ,  A23L5/44 ,  A23L33/155 ,  A61K9/107 ,  A61K31/015 ,  A61K33/32 ,  A61P3/02 ,  C07C403/24 ,  A61K31/595

公开(公告)号：ES2066306T3

公开(公告)日：1995-03-01

申请号：ES91116027

申请日：1991-09-20

Applicant: BASF AG

Inventor： END LUTZ DR ,  HORN DIETER DR ,  LUEDDECKE ERIK DR ,  SCHNEIDER JOACHIM U DR ,  HOPPE PETER PAUL DR ,  RENSMANN FRIEDRICH-WILHELM DR

IPC: A61K9/00 ,  A61K9/107 ,  A61K9/08 ,  A61K31/015 ,  A61K31/07 ,  A61K47/14 ,  A61P15/00 ,  C07B63/04 ,  C07C403/24 ,  C09K23/00

Abstract: Method for the continuous preparation of beta -carotene solubilisates by brief heating of beta -carotene together with an emulsifier until solution takes place, rapid cooling of the homogeneous solution to below 100 DEG C by addition of water and subsequent adjustment of the required final concentrations of beta -carotene, which is characterised in that a suspension, which has been preheated to 20 to 80 DEG C, of 1 to 40% by weight beta -carotene in an emulsifier is pumped through a heating coil located in a heat-transfer oil, where the temperature in the solubilisation mixture is 120 to 180 DEG C and the residence time is 10 to 300 seconds, and the homogeneous solution is turbulently mixed in a mixing chamber with such quantities of water at 10 to 80 DEG C that a solubilisate containing 0.5 to 6% by weight beta -carotene is produced and is, where appropriate, further diluted to the required final concentration.

公开(公告)号：DE19641939A1

公开(公告)日：1998-04-16

申请号：DE19641939

申请日：1996-10-11

Applicant: BASF AG

Inventor： RUNGE FRANK DR ,  ZWISSLER GEORG KONRAD DR ,  HORN DIETER DR ,  END LUTZ DR ,  KOBER REINER DR ,  SCHNEIDER KARL-HEINRICH DR ,  STADLER REINHOLD DR ,  ZIEGLER HANS DR ,  RADEMACHER WILHELM DR ,  SCHMIDT OSKAR DR ,  HARRIES VOLKER DR ,  SAUR REINHOLD DR

IPC: A01N25/14 ,  A01N25/26 ,  A01N57/16 ,  A01P3/00 ,  A01P13/00 ,  A01P21/00 ,  A01N57/14

Abstract: Plant protection formulation, in solid form comprises: (a) one or more essentially amorphous active agents with a water solubility of less than 500 mg/l at 25 deg C; and (b) a coating around component (a).

公开(公告)号：DE4031094A1

公开(公告)日：1992-04-09

申请号：DE4031094

申请日：1990-10-02

Applicant: BASF AG

Inventor： END LUTZ DR ,  HORN DIETER DR ,  LUEDDECKE ERIK DR ,  SCHNEIDER JOACHIM U DR ,  HOPPE PETER PAUL DR MED ,  RENSMANN FRIEDRICH-WILHELM DR

IPC: A61K9/08 ,  A61K9/00 ,  A61K9/107 ,  A61K31/015 ,  A61K31/07 ,  A61K47/14 ,  A61P15/00 ,  C07B63/04 ,  C07C403/24 ,  C09K23/00

Abstract: Method for the continuous preparation of beta -carotene solubilisates by brief heating of beta -carotene together with an emulsifier until solution takes place, rapid cooling of the homogeneous solution to below 100 DEG C by addition of water and subsequent adjustment of the required final concentrations of beta -carotene, which is characterised in that a suspension, which has been preheated to 20 to 80 DEG C, of 1 to 40% by weight beta -carotene in an emulsifier is pumped through a heating coil located in a heat-transfer oil, where the temperature in the solubilisation mixture is 120 to 180 DEG C and the residence time is 10 to 300 seconds, and the homogeneous solution is turbulently mixed in a mixing chamber with such quantities of water at 10 to 80 DEG C that a solubilisate containing 0.5 to 6% by weight beta -carotene is produced and is, where appropriate, further diluted to the required final concentration.

公开(公告)号：DE4329446A1

公开(公告)日：1995-03-02

申请号：DE4329446

申请日：1993-09-01

Applicant: BASF AG

Inventor： END LUTZ DR ,  HORN DIETER DR ,  LUEDDECKE ERIK DR

IPC: B01J13/04 ,  A61K9/14 ,  A61K9/16 ,  B01J2/04 ,  B01J2/06 ,  B01J13/00 ,  C09B61/00 ,  C09B67/00 ,  C09B67/42 ,  C09B67/46 ,  C09K23/00 ,  B01J13/02 ,  B01F17/00

Abstract: Process for producing finely divided, essentially amorphic colorant or active compound preparations by converting a relatively coarsely particulate dispersion or a solution into a colloidal distribution state in water, the colloidal distribution being generated at a temperature above the melting point of the colorant or active compound by adding appropriately hot water (if necessary under pressure) or an aqueous protective colloidal solution, so that an emulsion is formed of a melt in an aqueous medium, which emulsion is immediately spray-dried or is converted into a suspension by cooling.

公开(公告)号：DE3936053A1

公开(公告)日：1991-05-02

申请号：DE3936053

申请日：1989-10-28

Applicant: BASF AG

Inventor： HORN DIETER DR ,  END LUTZ DR ,  SPENGLER REINHARD DR ,  KRAUSE HANS-JUERGEN DR ,  ELZNER JUERGEN DR

IPC: A61K9/14 ,  A61K9/50 ,  A61K38/00 ,  C07K1/00 ,  C07K14/52 ,  C07K14/555 ,  C07K14/57 ,  C07K14/705 ,  C07K14/81

公开(公告)号：DE19653410A1

公开(公告)日：1998-06-25

申请号：DE19653410

申请日：1996-12-20

Applicant: BASF AG

Inventor： RUNGE FRANK DR ,  ZWISSLER GEORG KONRAD DR ,  END LUTZ DR ,  SCHWEIKERT LONI DR ,  HORN DIETER DR

IPC: A23C9/13 ,  A23C9/152 ,  A23C19/09 ,  A23D7/005 ,  A23D7/01 ,  A23D7/04 ,  A23L2/58 ,  A23L5/44 ,  A61K47/06 ,  C07C403/24 ,  C09B61/00 ,  C09B67/20 ,  A23L1/275 ,  A61K47/00 ,  A23L1/03 ,  A23L2/52 ,  A23D7/00 ,  A23C23/00

Abstract: Use of a carotenoid solubilisate, comprising 1-40 wt.% carotenoids, 20-90 wt.% non-ionic emulsifier and 0-50 wt.% other additives, to colour foodstuffs and pharmaceutical preparations. The ingredients are heated to 120-200 degrees C for a short time, water is added together with anti-oxidants or other additives, mixing at 10-95 degrees C occurs and the final formulation contains 0.5-10 wt.% carotinoids.