公开(公告)号：ES2066306T3

公开(公告)日：1995-03-01

申请号：ES91116027

申请日：1991-09-20

Applicant: BASF AG

Inventor： END LUTZ DR ,  HORN DIETER DR ,  LUEDDECKE ERIK DR ,  SCHNEIDER JOACHIM U DR ,  HOPPE PETER PAUL DR ,  RENSMANN FRIEDRICH-WILHELM DR

IPC: A61K9/00 ,  A61K9/107 ,  A61K9/08 ,  A61K31/015 ,  A61K31/07 ,  A61K47/14 ,  A61P15/00 ,  C07B63/04 ,  C07C403/24 ,  C09K23/00

Abstract: Method for the continuous preparation of beta -carotene solubilisates by brief heating of beta -carotene together with an emulsifier until solution takes place, rapid cooling of the homogeneous solution to below 100 DEG C by addition of water and subsequent adjustment of the required final concentrations of beta -carotene, which is characterised in that a suspension, which has been preheated to 20 to 80 DEG C, of 1 to 40% by weight beta -carotene in an emulsifier is pumped through a heating coil located in a heat-transfer oil, where the temperature in the solubilisation mixture is 120 to 180 DEG C and the residence time is 10 to 300 seconds, and the homogeneous solution is turbulently mixed in a mixing chamber with such quantities of water at 10 to 80 DEG C that a solubilisate containing 0.5 to 6% by weight beta -carotene is produced and is, where appropriate, further diluted to the required final concentration.

公开(公告)号：DE4031094A1

公开(公告)日：1992-04-09

申请号：DE4031094

申请日：1990-10-02

Applicant: BASF AG

Inventor： END LUTZ DR ,  HORN DIETER DR ,  LUEDDECKE ERIK DR ,  SCHNEIDER JOACHIM U DR ,  HOPPE PETER PAUL DR MED ,  RENSMANN FRIEDRICH-WILHELM DR

IPC: A61K9/08 ,  A61K9/00 ,  A61K9/107 ,  A61K31/015 ,  A61K31/07 ,  A61K47/14 ,  A61P15/00 ,  C07B63/04 ,  C07C403/24 ,  C09K23/00

Abstract: Method for the continuous preparation of beta -carotene solubilisates by brief heating of beta -carotene together with an emulsifier until solution takes place, rapid cooling of the homogeneous solution to below 100 DEG C by addition of water and subsequent adjustment of the required final concentrations of beta -carotene, which is characterised in that a suspension, which has been preheated to 20 to 80 DEG C, of 1 to 40% by weight beta -carotene in an emulsifier is pumped through a heating coil located in a heat-transfer oil, where the temperature in the solubilisation mixture is 120 to 180 DEG C and the residence time is 10 to 300 seconds, and the homogeneous solution is turbulently mixed in a mixing chamber with such quantities of water at 10 to 80 DEG C that a solubilisate containing 0.5 to 6% by weight beta -carotene is produced and is, where appropriate, further diluted to the required final concentration.

公开(公告)号：DE59103790D1

公开(公告)日：1995-01-19

申请号：DE59103790

申请日：1991-09-20

Applicant: BASF AG

Inventor： END LUTZ DR ,  HORN DIETER DR ,  LUEDDECKE ERIK DR ,  SCHNEIDER JOACHIM U DR ,  HOPPE PETER PAUL DR ,  RENSMANN FRIEDRICH-WILHELM DR

IPC: A61K9/08 ,  A61K9/00 ,  A61K9/107 ,  A61K31/015 ,  A61K31/07 ,  A61K47/14 ,  A61P15/00 ,  C07B63/04 ,  C07C403/24 ,  C09K23/00

Abstract: Method for the continuous preparation of beta -carotene solubilisates by brief heating of beta -carotene together with an emulsifier until solution takes place, rapid cooling of the homogeneous solution to below 100 DEG C by addition of water and subsequent adjustment of the required final concentrations of beta -carotene, which is characterised in that a suspension, which has been preheated to 20 to 80 DEG C, of 1 to 40% by weight beta -carotene in an emulsifier is pumped through a heating coil located in a heat-transfer oil, where the temperature in the solubilisation mixture is 120 to 180 DEG C and the residence time is 10 to 300 seconds, and the homogeneous solution is turbulently mixed in a mixing chamber with such quantities of water at 10 to 80 DEG C that a solubilisate containing 0.5 to 6% by weight beta -carotene is produced and is, where appropriate, further diluted to the required final concentration.

公开(公告)号：DK0479066T3

公开(公告)日：1995-02-13

申请号：DK91116027

申请日：1991-09-20

Applicant: BASF AG

Inventor： HORN DIETER DR ,  END LUTZ DR ,  LUEDDECKE ERIK DR ,  SCHNEIDER JOACHIM U DR ,  HOPPE PETER PAUL DR ,  RENSMANN FRIEDRICH-WILHELM DR

IPC: A61K9/00 ,  A61K9/107 ,  A61K31/015 ,  A61K9/08 ,  A61K31/07 ,  A61K47/14 ,  A61P15/00 ,  C07B63/04 ,  C07C403/24 ,  C09K23/00

Abstract: Method for the continuous preparation of beta -carotene solubilisates by brief heating of beta -carotene together with an emulsifier until solution takes place, rapid cooling of the homogeneous solution to below 100 DEG C by addition of water and subsequent adjustment of the required final concentrations of beta -carotene, which is characterised in that a suspension, which has been preheated to 20 to 80 DEG C, of 1 to 40% by weight beta -carotene in an emulsifier is pumped through a heating coil located in a heat-transfer oil, where the temperature in the solubilisation mixture is 120 to 180 DEG C and the residence time is 10 to 300 seconds, and the homogeneous solution is turbulently mixed in a mixing chamber with such quantities of water at 10 to 80 DEG C that a solubilisate containing 0.5 to 6% by weight beta -carotene is produced and is, where appropriate, further diluted to the required final concentration.