1.
    发明专利
    未知

    公开(公告)号:DE59800397D1

    公开(公告)日:2001-02-01

    申请号:DE59800397

    申请日:1998-01-29

    Applicant: BASF AG

    Abstract: Purification of alpha , beta , gamma -substituted carboxylic acids of formula (I), their salts and esters or a mixture of these and one or more polyol and one or more aminoalcohol in aqueous solution comprises treatment by electrodialysis. R1 = H, 1-10C alkyl, Na or K ; R2 = H or 1-10C alkyl; R3 = H, 1-10C alkyl (optionally substituted by NH2, OH, 1-4C alkyl, 1-4C alkoxy or halo-substituted phenyl); X = halo (when R3 is absent), N, O, P, S; and m = 0-2. Also claimed are: (i) cleavage of an optically active amide to an optically active amine and (I); and (ii) resolution of a racemic primary or secondary amine by reacting (I) with a hydrolase, separating the unreacted enantiomer of the amine from the amide and hydrolysing the amide to give the amine enantiomer and (I).

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