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1.
公开(公告)号:DE3475748D1
公开(公告)日:1989-02-02
申请号:DE3475748
申请日:1984-08-20
Applicant: BASF AG
Inventor: HERR DIETER DR
IPC: C08B37/10 , A61K9/48 , A61K31/715 , A61K45/08 , A61K47/10 , A61K47/14 , A61K47/26 , A61P7/02 , A61K31/725
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公开(公告)号:DE3866686D1
公开(公告)日:1992-01-16
申请号:DE3866686
申请日:1988-12-15
Applicant: BASF AG
Inventor: HERR DIETER DR , DOERPER THOMAS DR , DAUM LOTHAR DR , GEISS KARL-HEINZ DR , MOELLER ACHIM DR
IPC: C08B37/10 , A61K20060101 , A61K31/715 , A61P31/12 , A61K31/725
Abstract: Polysulphated heparins (I) are used to prepare medicaments for prophylaxis and therapy of diseases caused by retroviruses. (I) have an S content of 13-15% and a molecular wt. of 2000-20,000 (esp. 2000-9000 for oral admin). They may be prepd. by converting heparin to the pyridinium salt and reacting this with ClSO3H in pyridine. The medicaments may be formulated for oral or parenteral admin., or as sprays. The daily dose is 10-1000 mg/kg oral or 0.1-10 mg/kg parenteral.
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公开(公告)号:DE3808353A1
公开(公告)日:1989-09-21
申请号:DE3808353
申请日:1988-03-12
Applicant: BASF AG
Inventor: DAUM LOTHAR DR , DOERPER THOMAS DR , GEISS KARL-HEINZ DR , HERR DIETER DR , SCHLICK ERICH DR
IPC: C12N9/99 , A61K31/505 , A61K31/52 , A61K31/715 , A61K38/00 , A61K38/19 , A61K38/21 , A61K39/395 , A61K45/06 , A61P31/12 , A61P37/00 , A61P43/00
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公开(公告)号:AT39418T
公开(公告)日:1989-01-15
申请号:AT84109890
申请日:1984-08-20
Applicant: BASF AG
Inventor: HERR DIETER DR
IPC: C08B37/10 , A61K9/48 , A61K31/715 , A61K45/08 , A61K47/10 , A61K47/14 , A61K47/26 , A61P7/02 , A61K31/725
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公开(公告)号:AT69953T
公开(公告)日:1991-12-15
申请号:AT88120960
申请日:1988-12-15
Applicant: BASF AG
Inventor: HERR DIETER DR , DOERPER THOMAS DR , DAUM LOTHAR DR , GEISS KARL-HEINZ DR , MOELLER ACHIM DR
IPC: C08B37/10 , A61K20060101 , A61K31/715 , A61P31/12 , A61K31/725
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公开(公告)号:DE3744119A1
公开(公告)日:1989-07-06
申请号:DE3744119
申请日:1987-12-24
Applicant: BASF AG
Inventor: HERR DIETER DR , DOERPER THOMAS DR , DAUM LOTHAR DR , GEISS KARL-HEINZ DR , MOELLER ACHIM DR
IPC: C08B37/10 , A61K20060101 , A61K31/715 , A61P31/12
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公开(公告)号:DE3331009A1
公开(公告)日:1985-03-14
申请号:DE3331009
申请日:1983-08-27
Applicant: BASF AG
Inventor: HERR DIETER DR
IPC: C08B37/10 , A61K9/48 , A61K31/715 , A61K45/08 , A61K47/10 , A61K47/14 , A61K47/26 , A61P7/02 , A61K9/08 , A61K31/795
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