公开(公告)号：JP2000060435A

公开(公告)日：2000-02-29

申请号：JP22160299

申请日：1999-08-04

Applicant: BASF AG

Inventor： KRAEMER KLAUS DR ,  BALDENIUS KAI-UWE DR ,  HOPPE PETER P

IPC: A23K20/105 ,  A23K20/174 ,  A23K50/75 ,  A61K31/045 ,  A61K31/12 ,  A61K31/22 ,  A61K31/353 ,  A23K1/16 ,  A23K1/18

Abstract: PROBLEM TO BE SOLVED: To enable the reduction of the content of the cholesterol in a poultry egg by a new method comprising the use of a cholesterol biosynthesis inhibitor having an isoprenoid structure. SOLUTION: A cholesterol biosynthesis inhibitor having an isoprenoid structure is used. Examples of the inhibitor are tocotrienols of formula I (R1 to R3 are each CH3, R1 and R3 are each CH3 and R2 is H, or the like) and terpenoids. As the terpenoid, a linalool of formula II (R is H or CO-acyl) or the like is preferred. The inhibitor is preferably used by compounding in a conventional feed for poultry. Commonly, it is compounded in an amount of 5-10,000 mg based on 1 kg of the feed. In the case of tocotrienol, it is preferably compounded in an amount of 5-5,000 mg per 1 kg of the feed. The content of cholesterol in a poultry egg, and the contents of triglycerides in an egg and/or plasma of poultry are preferably reduced.

公开(公告)号：HU185159B

公开(公告)日：1984-12-28

申请号：HU387381

申请日：1981-12-18

Applicant: BASF AG

Inventor： HOPPE PETER P ,  SCHNEIDER JOACHIM U ,  SCHULZ BERNHARD ,  TIEFENBACHER HUBERT

IPC: A61K9/00 ,  A61K9/107 ,  A61K47/14 ,  A61K47/26 ,  A61K47/44 ,  A61K31/015 ,  A61K9/10

Abstract: A process for the preparation of beta -carotene micellar solutions, wherein a non-ionic emulsifier which is suitable for the preparation of micellar solutions is heated at from 160 DEG to 180 DEG C. and a total of from 20 to 30% by weight, based on the emulsifier, of beta -carotene is introduced in the presence of a conventional antioxidant, the hot homogeneous mixture is cooled rapidly to below 100 DEG C. by adding water, and the formulation is brought to the desired concentration of from 3 to 6% by weight by adding further water, and the beta -carotene micellar solutions obtained by this process. The non-ionic emulsifiers used in this process have an HLB value of from 12 to 16, and are in particular oxyethylated triglycerides of fatty acids of 12 to 18 carbon atoms containing 20-60 oxyethylene units. Parenteral admininstration of the stable beta -carotene micellar solutions according to the invention to cattle relieves the disturbed estrus cycle and impaired fertility caused by beta -carotene deficiency.

公开(公告)号：CA1235940A

公开(公告)日：1988-05-03

申请号：CA451103

申请日：1984-04-02

Applicant: BASF AG

Inventor： LECHTKEN PETER ,  NUERRENBACH AXEL ,  KOHLER WALTER ,  HOPPE PETER P ,  TIEFENBACHER HUBERT ,  SCHOLE JUERGEN

IPC: A23K1/16 ,  A23K1/18 ,  A61K9/40 ,  A61K31/47 ,  A61K31/495 ,  A61P3/00 ,  C07D215/58 ,  C07D265/36

Abstract: A growth-promoting additive for feeds consists of a commercial growth promoter as well as an aminoreductone of the formula I where R1, R2 and R3 are each hydrogen, methyl or ethyl and R4 is an unsubstituted or substituted C1-C20-alkyl or alkenyl radical or a radical of an aminoacid.

公开(公告)号：CA1185185A

公开(公告)日：1985-04-09

申请号：CA391630

申请日：1981-12-07

Applicant: BASF AG

Inventor： HOPPE PETER P ,  SCHNEIDER JOACHIM U ,  SCHULZ BERNHARD ,  TIEFENBACHER HUBERT

IPC: A61K9/00 ,  A61K9/107 ,  A61K47/14 ,  A61K47/26 ,  A61K47/44 ,  A61K31/23

Abstract: A process for the preparation of .beta.-carotene micellar solutions, wherein a non-ionic emulsifier which is suitable for the preparation of micellar solutions is heated at from 160 to 180.degree.C and a total of from 20 to 30% by weight, based on the emulsifier, of .beta.-carotene is introduced in the presence of a conventional antioxidant, the hot homogeneous mixture is cooled rapidly to below 100.degree.C by adding water, and the formulation is brought to the desired concentration of from 3 to 6% by weight by adding further water, and the .beta.-carotene micellar solutions obtained by this process. The non-ionic emulsifiers used in this process have an HLB value of from 12 to 16, and are in particular oxyethylated triglycerides of fatty acids of 12 to 18 carbon atoms containing 20 - 60 oxyethylene units. Parenteral administration of the stable .beta.-carotene micellar solutions according to the invention to cattle relieves the disturbed estrus cycle and impaired fertility caused by .beta.-carotene deficiency.