公开(公告)号：WO2005005629A3

公开(公告)日：2005-02-10

申请号：PCT/EP2004007229

申请日：2004-07-02

Applicant: BASF AG ,  LACOUR THIERRY ,  RETHER JAN ,  FREUND ANNETTE ,  LOESCH ANKE ,  JENCZMIONKA NICOLE ,  SCHAEFER WILHELM ,  MAIER FRANK ,  MALZ SASCHA ,  SCHMIDT RALF-MICHAEL

Inventor： LACOUR THIERRY ,  RETHER JAN ,  FREUND ANNETTE ,  LOESCH ANKE ,  JENCZMIONKA NICOLE ,  SCHAEFER WILHELM ,  MAIER FRANK ,  MALZ SASCHA ,  SCHMIDT RALF-MICHAEL

IPC: C12N9/12 ,  C12Q1/48

CPC classification number: C12N9/1241 ,  C12Q1/48

Abstract: The present invention relates to the provision of a polypeptide with the enzymatic activity of a Uridyl glucose pyrophosphorylase as targets for fungicides, the provision of novel nucleic acid sequences encoding a polypeptide with the enzymatic activity of a Uridyl glucose pyrophosphorylase, the provision of functional equivalents of the aforementioned nucleic acid sequences, and use of a polypeptide with the enzymatic activity of a Uridyl glucose pyrophosphorylase encoded by a nucleic acid sequence in a method for identifying antifungal compounds. Furthermore, the invention relates to antifungal compounds identified by the abovementioned method and the use of these compounds as fungicides.

Abstract translation: 本发明涉及提供具有乌吡啶葡萄糖焦磷酸化酶作为杀真菌剂靶的酶活性的多肽，提供编码具有乌吡啶葡萄糖焦磷酸化酶的酶活性的多肽的新型核酸序列，提供功能等同物 上述核酸序列，以及在鉴定抗真菌化合物的方法中使用由核酸序列编码的乌吡啶葡萄糖焦磷酸化酶的酶活性的多肽。 此外，本发明涉及通过上述方法鉴定的抗真菌化合物和这些化合物作为杀真菌剂的用途。

公开(公告)号：DE10150677A1

公开(公告)日：2003-04-30

申请号：DE10150677

申请日：2001-10-17

Applicant: BASF AG

Inventor： FREUND ANNETTE ,  SCHAEFER WILHELM ,  MAIER FRANK ,  LOESCH ANKE ,  MALZ SASCHA ,  JENCZMIONKA NICOLE ,  QUESTER KATRIN ,  ANDERMANN MEIKE

IPC: C12N9/12 ,  C12N15/31 ,  C12N15/54 ,  C12Q1/18 ,  C12Q1/48 ,  C12Q1/68 ,  C12Q1/6895 ,  C07H21/00 ,  C12Q1/02

Abstract: Nucleic acid sequence, encoding a MAP kinase, (I) comprises (a) sequences (S1) or (S2), of 556 and 490 nucleotides, reproduced; (b) a functional equivalent of (a); (c) a fragment of (a); or (d) a sequence that contains part of (a). Independent claims are also included for the following: (1) Expression cassette (EC) that contains (I); (2) Vector (III) that contains EC; (3) Transgenic organism that contains at least one (I), EC or (III); (4) Identifying (M4) fungicidal compounds from their ability to reduce, inhibit or block transcription, expression, translation or activity of the products of (I); and (5) Fungicides identified by (M4).