公开(公告)号：WO2004005522A3

公开(公告)日：2004-06-03

申请号：PCT/EP0307028

申请日：2003-07-02

Applicant: BASF AG ,  LACOUR THIERRY ,  RETHER JAN ,  FREUND ANNETTE ,  SCHAEFER WILHELM ,  MAIER FRANK ,  MALZ SASCHA

Inventor： LACOUR THIERRY ,  RETHER JAN ,  FREUND ANNETTE ,  SCHAEFER WILHELM ,  MAIER FRANK ,  MALZ SASCHA

IPC: C12N15/80 ,  C12N9/10 ,  C12N15/52

CPC classification number: C12N15/80

Abstract: The invention relates to novel plasmid vectors for transformation of filamentous fungi and to a method of modifiying the genome of filamentous fungi based on these vectors. The invention furthermore relates to the modification of a specific gene via the process of homologous recombination, to recombinant expression of foreign genes in filamentous fungi and to new selection markers for detecting succesfull transfer of the target gene in filamentous fungi.

Abstract translation: 本发明涉及用于转化丝状真菌的新型质粒载体和基于这些载体修饰丝状真菌基因组的方法。 本发明还涉及通过同源重组的方法修饰特定基因，重组外源基因在丝状真菌中的表达，以及用于检测丝状真菌中靶基因成功转移的新选择标记。

公开(公告)号：WO2005068635A3

公开(公告)日：2005-11-03

申请号：PCT/EP2004014826

申请日：2004-12-30

Applicant: BASF AG ,  LACOUR THIERRY ,  SCHAEFER WILHELM ,  MAIER FRANK

Inventor： LACOUR THIERRY ,  SCHAEFER WILHELM ,  MAIER FRANK

IPC: C07K14/37 ,  C07K14/39 ,  C07K14/435 ,  C12Q1/18 ,  C12Q1/68 ,  C12N15/52 ,  C12N9/02 ,  C12N15/80 ,  C12N15/81

CPC classification number: C12Q1/6897 ,  C07K14/37 ,  C07K14/39 ,  C12Q1/6895

Abstract: The present invention relates to the provision of expression cassettes and nucleic acid sequences and to the use of these aforementioned nucleic acid sequences in a method for identifying antifungal compounds, which inhibit the mitochondrial transport process in eucaryotes. Furthermore, the invention relates to the use of these compounds identified via the abovementioned method as fungicides.

Abstract translation: 本发明涉及提供表达盒和核酸序列，以及这些上述核酸序列用于鉴定抑制真核生物中的线粒体转运过程的抗真菌化合物的方法中的用途。 此外，本发明涉及通过上述方法鉴定的这些化合物作为杀真菌剂的用途。

公开(公告)号：WO2005005629A3

公开(公告)日：2005-02-10

申请号：PCT/EP2004007229

申请日：2004-07-02

Applicant: BASF AG ,  LACOUR THIERRY ,  RETHER JAN ,  FREUND ANNETTE ,  LOESCH ANKE ,  JENCZMIONKA NICOLE ,  SCHAEFER WILHELM ,  MAIER FRANK ,  MALZ SASCHA ,  SCHMIDT RALF-MICHAEL

Inventor： LACOUR THIERRY ,  RETHER JAN ,  FREUND ANNETTE ,  LOESCH ANKE ,  JENCZMIONKA NICOLE ,  SCHAEFER WILHELM ,  MAIER FRANK ,  MALZ SASCHA ,  SCHMIDT RALF-MICHAEL

IPC: C12N9/12 ,  C12Q1/48

CPC classification number: C12N9/1241 ,  C12Q1/48

Abstract: The present invention relates to the provision of a polypeptide with the enzymatic activity of a Uridyl glucose pyrophosphorylase as targets for fungicides, the provision of novel nucleic acid sequences encoding a polypeptide with the enzymatic activity of a Uridyl glucose pyrophosphorylase, the provision of functional equivalents of the aforementioned nucleic acid sequences, and use of a polypeptide with the enzymatic activity of a Uridyl glucose pyrophosphorylase encoded by a nucleic acid sequence in a method for identifying antifungal compounds. Furthermore, the invention relates to antifungal compounds identified by the abovementioned method and the use of these compounds as fungicides.

Abstract translation: 本发明涉及提供具有乌吡啶葡萄糖焦磷酸化酶作为杀真菌剂靶的酶活性的多肽，提供编码具有乌吡啶葡萄糖焦磷酸化酶的酶活性的多肽的新型核酸序列，提供功能等同物 上述核酸序列，以及在鉴定抗真菌化合物的方法中使用由核酸序列编码的乌吡啶葡萄糖焦磷酸化酶的酶活性的多肽。 此外，本发明涉及通过上述方法鉴定的抗真菌化合物和这些化合物作为杀真菌剂的用途。

公开(公告)号：DE10150677A1

公开(公告)日：2003-04-30

申请号：DE10150677

申请日：2001-10-17

Applicant: BASF AG

Inventor： FREUND ANNETTE ,  SCHAEFER WILHELM ,  MAIER FRANK ,  LOESCH ANKE ,  MALZ SASCHA ,  JENCZMIONKA NICOLE ,  QUESTER KATRIN ,  ANDERMANN MEIKE

IPC: C12N9/12 ,  C12N15/31 ,  C12N15/54 ,  C12Q1/18 ,  C12Q1/48 ,  C12Q1/68 ,  C12Q1/6895 ,  C07H21/00 ,  C12Q1/02

Abstract: Nucleic acid sequence, encoding a MAP kinase, (I) comprises (a) sequences (S1) or (S2), of 556 and 490 nucleotides, reproduced; (b) a functional equivalent of (a); (c) a fragment of (a); or (d) a sequence that contains part of (a). Independent claims are also included for the following: (1) Expression cassette (EC) that contains (I); (2) Vector (III) that contains EC; (3) Transgenic organism that contains at least one (I), EC or (III); (4) Identifying (M4) fungicidal compounds from their ability to reduce, inhibit or block transcription, expression, translation or activity of the products of (I); and (5) Fungicides identified by (M4).