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公开(公告)号:JP2000178250A
公开(公告)日:2000-06-27
申请号:JP35933999
申请日:1999-12-17
Applicant: BASF AG
Inventor: GROENING CARSTEN DR , KEMPER REINHARD , FREDE MARKUS DR , EBEL KLAUS DR
IPC: C07D207/32 , C07D207/323
Abstract: PROBLEM TO BE SOLVED: To produce 2,4-dimethylpyrrole under much milder conditions of slighter aggressiveness thin well-known conditions according to a conventional technique. SOLUTION: A dicarboxylic acid alkyl ester which is a 2,4-dimethyl-3,5- bisalkoxycarbonylpyrrole is refluxed together with an aqueous solution of an alkali metal hydroxide at 10-30% concentration, advantageously a sodium hydroxide solution until a solid is converted into a solution and the reactional mixture is then neutralized with an acid and further refluxed until the decarbocylation is completed, i.e., the gas evolution is stopped.
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公开(公告)号:JP2000178251A
公开(公告)日:2000-06-27
申请号:JP35934099
申请日:1999-12-17
Applicant: BASF AG
Inventor: GROENING CARSTEN DR , KEMPER REINHARD , FREDE MARKUS DR , EBEL KLAUS DR
IPC: C07D241/06 , B01J23/44 , C07B61/00 , C07D207/34
Abstract: PROBLEM TO BE SOLVED: To produce a 2,4-dimethyl-3,5-bisalkoxycarbonylpyrrole by enabling operations under milder conditions than those of a conventional technique and avoidance of the formation of by-products. SOLUTION: An alkyl acetoacetate is nitrosated to produce an alkyl 2- nitrosoacetoacetate, which is then reduced with hydrogen in the presence of a noble metal catalyst to form an amine. The resultant amino compound without isolation is condensed in the presence of the corresponding alkyl acetoacetate without undergoing the nitrosation to produce 2,4-dimethyl-3,5- bisalkoxycarbonylpyrrole.
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公开(公告)号:GB2177105B
公开(公告)日:1989-07-19
申请号:GB8616391
申请日:1986-07-04
Applicant: BASF AG
Inventor: LOTSCH WOLFGANG , KEMPER REINHARD
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公开(公告)号:GB2178049B
公开(公告)日:1988-12-14
申请号:GB8617776
申请日:1986-07-21
Applicant: BASF AG
Inventor: LOTSCH WOLFGANG , KEMPER REINHARD
IPC: C09B57/04
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公开(公告)号:DE10116316A1
公开(公告)日:2002-10-24
申请号:DE10116316
申请日:2001-04-02
Applicant: BASF AG
Inventor: STROEFER ECKHARD , SOHN MARTIN , LANGENSIEPEN HANS-WERNER , MUELLER CHRISTIAN , KRUG GEORG , KEMPER REINHARD
IPC: C07C209/78 , C07C211/50 , C07C209/60
Abstract: A process for the production of 4,4'-diaminoditolylmethane comprises reaction of o-toluidine with formaldehyde in the presence of an acid catalyst whereby the ratio of acid catalyst to o-toluidine is 0.8-1.2 equivalents of acid per mole of o-toluidine. providing a process for the production of 4,4'-diaminoditolylmethane.
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公开(公告)号:GB2177104B
公开(公告)日:1988-12-21
申请号:GB8615483
申请日:1986-06-25
Applicant: BASF AG
Inventor: HAHN ERWIN , LOTSCH WOLFGANG , KEMPER REINHARD
IPC: C08K5/00 , C07D209/44 , C08K5/34 , C08K5/3412 , C09B57/04
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公开(公告)号:GB2177105A
公开(公告)日:1987-01-14
申请号:GB8616391
申请日:1986-07-04
Applicant: BASF AG
Inventor: LOTSCH WOLFGANG , KEMPER REINHARD
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公开(公告)号:DE19858360A1
公开(公告)日:2000-06-21
申请号:DE19858360
申请日:1998-12-17
Applicant: BASF AG
Inventor: GROENING CARSTEN , KEMPER REINHARD , FREDE MARKUS , EBEL KLAUS
IPC: C07D207/32 , C07D207/323 , C07D207/416
Abstract: In the preparation of 2,4-dimethyl-pyrrole (I) by hydrolysis of 2,4-dimethyl-3,5-bis-alkoxycarbonyl-pyrrole (II) to the dicarboxylic acid (III) with strong alkali and thermal decarboxylation of (III), (II) is heated under reflux with 10-30% aqueous alkali hydroxide, and then neutralized with acid. Heating under reflux is continued to complete decarboxylation.
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公开(公告)号:DE19858352A1
公开(公告)日:2000-06-21
申请号:DE19858352
申请日:1998-12-17
Applicant: BASF AG
Inventor: GROENING CARSTEN , KEMPER REINHARD , FREDE MARKUS , EBEL KLAUS
IPC: C07D241/06 , B01J23/44 , C07B61/00 , C07D207/34 , C07D207/416
Abstract: In the preparation of 2,4-dimethyl-3,5-bis-alkoxycarbonyl-pyrroles (I) by nitrosing an alkyl acetoacetate (II) to the alkyl 2-nitrosoacetoacetate (III), reducing (III) to the amine (IV) and ring-closing condensation with unsubstituted (II), (III) is hydrogenated with hydrogen in the presence of a noble metal catalyst and condensed with (II) without isolating (IV).
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公开(公告)号:GB2178049A
公开(公告)日:1987-02-04
申请号:GB8617776
申请日:1986-07-21
Applicant: BASF AG
Inventor: LOTSCH WOLFGANG , KEMPER REINHARD
IPC: C09B57/04
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