公开(公告)号：DE59104561D1

公开(公告)日：1995-03-23

申请号：DE59104561

申请日：1991-03-21

Applicant: BASF AG

Inventor： MERGER FRANZ DR ,  PRIESTER CLAUS-ULRICH DR ,  KLOPPENHOEFER GERHARD DR ,  HARDER WOLFGANG DR ,  WITZEL TOM DR ,  LERMER HELMUT DR ,  KOEHLER ULRICH DR

IPC: B01J23/40 ,  B01J23/74 ,  B01J29/06 ,  C07B61/00 ,  C07C209/00 ,  C07C209/26 ,  C07C209/48 ,  C07C211/36

Abstract: Process for the preparation of 2-(3-aminopropyl)cycloalkylamines of the general formula I in which the index n is an integer from 1 to 4, from 2-(2-cyanoethyl)cycloalkanones of the general formula II in which the index n has the abovementioned meaning, by carrying out the following steps in two reaction spaces spatially separated from one another: a) reacting the 2-(2-cyanoethyl)cycloalkanones of the formula II in a first reaction space with excess ammonia over acidic heterogeneous catalysts at temperatures of 20 to 150 DEG C and pressures of 15 to 500 bar and b) hydrogenating the reaction products in a second reaction space with hydrogen in the presence of excess ammonia over cobalt-, nickel-, ruthenium- and/or other noble metal-containing catalysts which may contain basic components or are present on neutral or basic supports at temperatures of 60 to 150 DEG C and pressures of 100 to 500 bar, and also the novel compound 2-(3-aminopropyl)cyclopentylamine.

公开(公告)号：ES2068412T3

公开(公告)日：1995-04-16

申请号：ES91104411

申请日：1991-03-21

Applicant: BASF AG

Inventor： MERGER FRANZ DR ,  PRIESTER CLAUS-ULRICH DR ,  KLOPPENHOEFER GERHARD DR ,  HARDER WOLFGANG DR ,  WITZEL TOM DR ,  LERMER HELMUT DR ,  KOEHLER ULRICH DR

IPC: B01J23/40 ,  B01J23/74 ,  B01J29/06 ,  C07B61/00 ,  C07C209/00 ,  C07C209/26 ,  C07C209/48 ,  C07C211/36

Abstract: Process for the preparation of 2-(3-aminopropyl)cycloalkylamines of the general formula I in which the index n is an integer from 1 to 4, from 2-(2-cyanoethyl)cycloalkanones of the general formula II in which the index n has the abovementioned meaning, by carrying out the following steps in two reaction spaces spatially separated from one another: a) reacting the 2-(2-cyanoethyl)cycloalkanones of the formula II in a first reaction space with excess ammonia over acidic heterogeneous catalysts at temperatures of 20 to 150 DEG C and pressures of 15 to 500 bar and b) hydrogenating the reaction products in a second reaction space with hydrogen in the presence of excess ammonia over cobalt-, nickel-, ruthenium- and/or other noble metal-containing catalysts which may contain basic components or are present on neutral or basic supports at temperatures of 60 to 150 DEG C and pressures of 100 to 500 bar, and also the novel compound 2-(3-aminopropyl)cyclopentylamine.