公开(公告)号：WO2007135188A2

公开(公告)日：2007-11-29

申请号：PCT/EP2007055056

申请日：2007-05-24

Applicant: BASF AG ,  ZELDER OSKAR ,  HEROLD ANDREA ,  KLOPPROGGE CORINNA ,  SCHROEDER HARTWIG ,  HEINZLE ELMAR ,  WITTMANN CHRISTOPH ,  KROEMER JENS ,  PERO JANICE ,  YOCUM ROGERS ,  PATTERSON THOMAS ,  WILLIAMS MARK ,  HERMANN THERON

Inventor： ZELDER OSKAR ,  HEROLD ANDREA ,  KLOPPROGGE CORINNA ,  SCHROEDER HARTWIG ,  HEINZLE ELMAR ,  WITTMANN CHRISTOPH ,  KROEMER JENS ,  PERO JANICE ,  YOCUM ROGERS ,  PATTERSON THOMAS ,  WILLIAMS MARK ,  HERMANN THERON

IPC: C12P13/12

CPC classification number: C12P13/12

Abstract: The present invention relates to microorganisms and processes for the efficient preparation of L-methionine. In particular, the present invention relates to processes in which the amount of serine available for the metabolism of the microorganism is increased.

Abstract translation: 本发明涉及用于L-甲硫氨酸有效制备的微生物和方法。 特别地，本发明涉及其中可用于微生物代谢的丝氨酸量增加的方法。

公开(公告)号：WO2007020295A3

公开(公告)日：2007-05-03

申请号：PCT/EP2006065460

申请日：2006-08-18

Applicant: BASF AG ,  ZELDER OSKAR ,  HEROLD ANDREA ,  KLOPPROGGE CORINNA ,  SCHROEDER HARTWIG ,  HAEFNER STEFAN ,  HEINZLE ELMAR ,  WITTMANN CHRISTOPH ,  KROEMER JENS ,  PERO JANICE ,  YOCUM ROGERS ,  PATTERSON THOMAS ,  WILLIAMS MARK ,  HERMAN THERON

Inventor： ZELDER OSKAR ,  HEROLD ANDREA ,  KLOPPROGGE CORINNA ,  SCHROEDER HARTWIG ,  HAEFNER STEFAN ,  HEINZLE ELMAR ,  WITTMANN CHRISTOPH ,  KROEMER JENS ,  PERO JANICE ,  YOCUM ROGERS ,  PATTERSON THOMAS ,  WILLIAMS MARK ,  HERMAN THERON

IPC: C12N15/52 ,  C12P13/12 ,  C12R1/13 ,  C12R1/19

CPC classification number: C12N15/52 ,  C12P13/12

Abstract: The present invention concerns methods for the production of microorganisms with increased efficiency for methionine synthesis. The present invention also concerns microorganisms with increased efficiency for methionine synthesis. Furthermore, the present invention concerns methods for determining the optimal metabolic flux for organisms with respect to methionine synthesis.

Abstract translation: 本发明涉及生产甲硫氨酸合成效率提高的微生物的方法。 本发明还涉及甲硫氨酸合成效率提高的微生物。 此外，本发明涉及用于确定与甲硫氨酸合成有关的生物体的最佳代谢通量的方法。

公开(公告)号：HU230549B1

公开(公告)日：2016-11-28

申请号：HU0302798

申请日：2002-01-19

Applicant: BASF AG

Inventor： HERMANN THERON ,  PATTERSON THOMAS ,  PERO JANICE G ,  YOCUM ROGER R ,  BALDENIUS KAI-UWE ,  BECK CHRISTINE

IPC: C12N15/09 ,  C12P13/02 ,  A61K31/7088 ,  A61P43/00 ,  C12N1/21 ,  C12N9/10 ,  C12P13/00 ,  C12P13/04 ,  C12R1/125

公开(公告)号：CA2620468A1

公开(公告)日：2007-02-22

申请号：CA2620468

申请日：2006-08-18

Applicant: BASF AG

Inventor： KROEMER JENS ,  SCHROEDER HARTWIG ,  WITTMANN CHRISTOPH ,  HEINZLE ELMAR ,  HAEFNER STEFAN ,  HEROLD ANDREA ,  ZELDER OSKAR ,  KLOPPROGGE CORINNA ,  PERO JANICE ,  YOCUM ROGERS ,  WILLIAMS MARK ,  HERMAN THERON ,  PATTERSON THOMAS

IPC: C12N15/52 ,  C12P13/12

Abstract: The present invention relates to methods for the production of microorganisms with increased efficiency for methionine synthesis, microorganisms with increased efficiency for methionine synthesis, and methods for determining the optimal metabolic flux for organisms with respect to methionine synthesis.

公开(公告)号：HU0302798A2

公开(公告)日：2003-11-28

申请号：HU0302798

申请日：2002-01-19

Applicant: BASF AG

Inventor： BALDENIUS KAI-UWE ,  BECK CHRISTINE ,  HERMANN THERON ,  PATTERSON THOMAS ,  PERO JANICE G ,  YOCUM ROGER R

IPC: C12N15/09 ,  A61K31/7088 ,  A61P43/00 ,  C12N1/21 ,  C12N9/10 ,  C12P13/00 ,  C12P13/02 ,  C12P13/04 ,  C12R1/125

Abstract: The present invention features improved methods for producing pantoate and pantothenate utilizing microorganisms having modified pantothenate biosynthetic enzyme activities. In particular, the invention features methods for reducing byproduct formation and increasing yields and purity of desired product. Recombinant microorganisms and conditions for culturing same are also are featured. Also featured are compositions produced by such microorganisms.