公开(公告)号：DK0481299T3

公开(公告)日：1994-09-12

申请号：DK91116915

申请日：1991-10-04

Applicant: BASF AG

Inventor： LUBISCH WILFRIED DR ,  SCHULT SABINE DR ,  BINDER RUDOLF DR ,  RASCHACK MANFRED DR ,  REINHARDT ROLAND DR ,  SEEMANN DIETMAR DR

IPC: A61K31/445 ,  A61K31/4427 ,  A61K31/4468 ,  A61P9/00 ,  C07D211/58 ,  C07D401/12 ,  A61K31/44

Abstract: Phenylpiperidylamines of the formula I I R1 is H, NO2, R4SO2NH, N=C, CF3, CF3O, F, Cl, Br, C1-C4-alkyl, R3O, CO2R3, CHO, CH=NOR3, CH3OR3 and R2 is H, F, Cl, Br, C1-C4-alkyl or R4O, where R1 and R2 are not both H, R3 is H or R4, R4 is C1-C4-alkyl or phenyl, n is 1, 2, 3 or 4 and Ar is and the physiologically tolerated salts thereof, are used as active ingredients in drugs.

公开(公告)号：DE4132013A1

公开(公告)日：1993-04-01

申请号：DE4132013

申请日：1991-09-26

Applicant: BASF AG

Inventor： LUBISCH WILFRIED DR ,  SCHULT SABINE DR ,  BINDER RUDOLF DR ,  RASCHACK MANFRED DR ,  REINHARDT ROLAND DR ,  SEEMANN DIETMAR DR

IPC: A61K31/165 ,  A61K31/18 ,  A61K31/415 ,  A61K31/44 ,  A61K31/4409 ,  A61K31/4418 ,  A61P9/06 ,  C07C217/58 ,  C07C233/80 ,  C07C255/54 ,  C07C255/57 ,  C07C311/08 ,  C07C311/21 ,  C07D213/30 ,  C07D213/38 ,  C07D213/71 ,  C07D213/81 ,  C07D233/60 ,  C07D233/61 ,  C07D295/096 ,  C07D295/135

公开(公告)号：DE59102245D1

公开(公告)日：1994-08-25

申请号：DE59102245

申请日：1991-10-04

Applicant: BASF AG

Inventor： LUBISCH WILFRIED DR ,  SCHULT SABINE DR ,  BINDER RUDOLF DR ,  RASCHACK MANFRED DR ,  REINHARDT ROLAND DR ,  SEEMANN DIETMAR DR

IPC: A61K31/445 ,  A61K31/4427 ,  A61K31/4468 ,  A61P9/00 ,  C07D211/58 ,  C07D401/12

Abstract: Phenylpiperidylamines of the formula I I R1 is H, NO2, R4SO2NH, N=C, CF3, CF3O, F, Cl, Br, C1-C4-alkyl, R3O, CO2R3, CHO, CH=NOR3, CH3OR3 and R2 is H, F, Cl, Br, C1-C4-alkyl or R4O, where R1 and R2 are not both H, R3 is H or R4, R4 is C1-C4-alkyl or phenyl, n is 1, 2, 3 or 4 and Ar is and the physiologically tolerated salts thereof, are used as active ingredients in drugs.

公开(公告)号：DE59106082D1

公开(公告)日：1995-08-31

申请号：DE59106082

申请日：1991-10-02

Applicant: BASF AG

Inventor： LUBISCH WILFRIED DR ,  SCHULT SABINE DR ,  BINDER RUDOLF DR ,  RASCHACK MANFRED DR ,  REINHARDT ROLAND DR ,  SEEMANN DIETMAR DR

IPC: A61K31/445 ,  A61K31/4468 ,  A61P9/00 ,  C07D211/58

Abstract: Phenylpiperidinylamines of the formula I I where R1 is -NHSO2R4 or R2 and R3 are each, independently of one another, H or C1-C4-alkyl or together are a (CH2)n chain with n=4 or 5, and R4 is C1-C4-alkyl or phenyl, and the physiologically tolerated salts thereof, and pharmaceutical compositions containing these are described.

公开(公告)号：AT125531T

公开(公告)日：1995-08-15

申请号：AT91116812

申请日：1991-10-02

Applicant: BASF AG

Inventor： LUBISCH WILFRIED DR ,  SCHULT SABINE DR ,  BINDER RUDOLF DR ,  RASCHACK MANFRED DR ,  REINHARDT ROLAND DR ,  SEEMANN DIETMAR DR

IPC: A61K31/445 ,  A61K31/4468 ,  A61P9/00 ,  C07D211/58

Abstract: Phenylpiperidinylamines of the formula I I where R1 is -NHSO2R4 or R2 and R3 are each, independently of one another, H or C1-C4-alkyl or together are a (CH2)n chain with n=4 or 5, and R4 is C1-C4-alkyl or phenyl, and the physiologically tolerated salts thereof, and pharmaceutical compositions containing these are described.

公开(公告)号：DE4032767A1

公开(公告)日：1992-04-30

申请号：DE4032767

申请日：1990-10-16

Applicant: BASF AG

Inventor： LUBISCH WILFRIED DR ,  SCHULT SABINE DR ,  BINDER RUDOLF DR ,  RASCHACK MANFRED DR ,  REINHARDT ROLAND DR ,  SEEMANN DIETMAR DR

IPC: A61K31/445 ,  A61K31/4468 ,  A61P9/00 ,  C07D211/58

Abstract: Phenylpiperidinylamines of the formula I I where R1 is -NHSO2R4 or R2 and R3 are each, independently of one another, H or C1-C4-alkyl or together are a (CH2)n chain with n=4 or 5, and R4 is C1-C4-alkyl or phenyl, and the physiologically tolerated salts thereof, and pharmaceutical compositions containing these are described.

公开(公告)号：DK0481288T3

公开(公告)日：1995-09-11

申请号：DK91116812

申请日：1991-10-02

Applicant: BASF AG

Inventor： LUBISCH WILFRIED DR ,  SCHULT SABINE DR ,  BINDER RUDOLF DR ,  RASCHACK MANFRED DR ,  REINHARDT ROLAND DR ,  SEEMANN DIETMAR DR

IPC: A61K31/445 ,  A61K31/4468 ,  A61P9/00 ,  C07D211/58

Abstract: Phenylpiperidinylamines of the formula I I where R1 is -NHSO2R4 or R2 and R3 are each, independently of one another, H or C1-C4-alkyl or together are a (CH2)n chain with n=4 or 5, and R4 is C1-C4-alkyl or phenyl, and the physiologically tolerated salts thereof, and pharmaceutical compositions containing these are described.

公开(公告)号：AT108775T

公开(公告)日：1994-08-15

申请号：AT91116915

申请日：1991-10-04

Applicant: BASF AG

Inventor： LUBISCH WILFRIED DR ,  SCHULT SABINE DR ,  BINDER RUDOLF DR ,  RASCHACK MANFRED DR ,  REINHARDT ROLAND DR ,  SEEMANN DIETMAR DR

IPC: A61K31/445 ,  A61K31/4427 ,  A61K31/4468 ,  A61P9/00 ,  C07D211/58 ,  C07D401/12

Abstract: Phenylpiperidylamines of the formula I I R1 is H, NO2, R4SO2NH, N=C, CF3, CF3O, F, Cl, Br, C1-C4-alkyl, R3O, CO2R3, CHO, CH=NOR3, CH3OR3 and R2 is H, F, Cl, Br, C1-C4-alkyl or R4O, where R1 and R2 are not both H, R3 is H or R4, R4 is C1-C4-alkyl or phenyl, n is 1, 2, 3 or 4 and Ar is and the physiologically tolerated salts thereof, are used as active ingredients in drugs.

公开(公告)号：DE4032766A1

公开(公告)日：1992-04-30

申请号：DE4032766

申请日：1990-10-16

Applicant: BASF AG

Inventor： LUBISCH WILFRIED DR ,  SCHULT SABINE DR ,  BINDER RUDOLF DR ,  RASCHACK MANFRED DR ,  REINHARDT ROLAND DR ,  SEEMANN DIETMAR DR

IPC: A61K31/445 ,  A61K31/4427 ,  A61K31/4468 ,  A61P9/00 ,  C07D211/58 ,  C07D401/12

Abstract: Phenylpiperidylamines of the formula I I R1 is H, NO2, R4SO2NH, N=C, CF3, CF3O, F, Cl, Br, C1-C4-alkyl, R3O, CO2R3, CHO, CH=NOR3, CH3OR3 and R2 is H, F, Cl, Br, C1-C4-alkyl or R4O, where R1 and R2 are not both H, R3 is H or R4, R4 is C1-C4-alkyl or phenyl, n is 1, 2, 3 or 4 and Ar is and the physiologically tolerated salts thereof, are used as active ingredients in drugs.