公开(公告)号：DK443881A

公开(公告)日：1982-04-09

申请号：DK443881

申请日：1981-10-07

Applicant: BASF AG

Inventor： STEINER G ,  TESCHENDORF H J ,  KREISKOTT H ,  HOFMANN H P

IPC: A61K31/55 ,  A61P25/00 ,  A61P25/08 ,  A61P25/20 ,  C07D223/00 ,  C07D333/00 ,  C07D495/14 ,  C07D

公开(公告)号：DK101781A

公开(公告)日：1981-09-09

申请号：DK101781

申请日：1981-03-06

Applicant: BASF AG

Inventor： STEINER G ,  HOFMANN H P ,  KREISKOTT H ,  TESCHENDORF H J ,  LENKE D

IPC: C07D295/14 ,  A61K31/275 ,  A61K31/395 ,  A61K31/50 ,  A61K31/55 ,  A61P25/20 ,  C07C67/00 ,  C07C253/00 ,  C07C255/37 ,  C07C255/42 ,  C07D243/08 ,  C07D295/08 ,  C07D295/155 ,  C07C

Abstract: 10-Substituted 5-cyanomethylene-dibenzo[a,d]-cycloheptenes, their pure cis- and trans-isomers, their N-oxides and their pharmaceutically tolerated addition salts with acids, processes for their preparation, therapeutic agents containing these compounds and their use as drugs, especially as sedatives, hypnotics or tranquilizers.

公开(公告)号：YU121380A

公开(公告)日：1984-02-29

申请号：YU121380

申请日：1980-05-07

Applicant: BASF AG

Inventor： TESCHENDORF H J ,  WORSTMANN W ,  KREISKOTT H

IPC: A61K31/55 ,  A61P25/18 ,  C07D223/20 ,  C07D401/06 ,  C07D403/04 ,  C07D498/04 ,  C07D401/04 ,  C07D233/00

Abstract: 6-Substituted 11-alkylene-morphanthridines, also referred to as 11-alkylene-dibenzo[b,e]-azepines, their pure cis- and trans-isomers, processes for their preparation, and therapeutic agents containing these compounds, which may be used as drugs, in particular neuroleptics, sedatives, hypnotics, analgesics, antidepressants or agents for treating Parkinson's syndrome.

公开(公告)号：DK130081A

公开(公告)日：1981-09-25

申请号：DK130081

申请日：1981-03-23

Applicant: BASF AG

Inventor： MAY H J ,  LENKE D ,  GRIES J ,  TESCHENDORF H J ,  WORSTMANN W

IPC: C07D409/06 ,  A61K31/33 ,  A61K31/415 ,  A61K31/465 ,  A61K31/47 ,  A61P9/08 ,  A61P9/10 ,  A61P9/12 ,  A61P43/00 ,  C07D233/54 ,  C07D233/64 ,  C07D401/06 ,  C07D403/06 ,  C07D405/06 ,  C07D413/06 ,  C07D417/06 ,  C07D

Abstract: 1-Aroyl-2-phenylamino-2-imidazolines of the general formula where R1 and R2 are identical or different and each is chlorine, bromine, fluorine, methyl, ethyl, methoxy, trifluoromethyl or cyano, R3 has the meanings given for R1 and R2 or is hydrogen and Ar is an unsubstituted or substituted monocyclic or bicyclic heteroaromatic radical containing 1, 2 or 3 nitrogen and/or oxygen and/or sulfur atoms, their salts with physiologically tolerated acids, their preparation, and drugs containing these compounds. The compounds have, inter alia, a blood pressure-reducing action.

公开(公告)号：DK19182A

公开(公告)日：1982-07-20

申请号：DK19182

申请日：1982-01-18

Applicant: BASF AG

Inventor： THIEME P C ,  STEINER G ,  ROHR W ,  LENKE D ,  GRIES J ,  WEIFENBACH H ,  TESCHENDORF H J ,  HOFMAN H P ,  KREISKOTT H

IPC: C07D249/08 ,  A61K31/41 ,  A61K31/415 ,  A61K31/495 ,  A61K31/496 ,  A61P9/02 ,  A61P11/00 ,  A61P25/20 ,  C07D231/12 ,  C07D233/60 ,  C07D233/61 ,  C07D271/10 ,  C07D295/06 ,  C07D295/067 ,  C07D295/096 ,  C07D521/00 ,  C07D

Abstract: Novel phenylpiperazinylpropane and -butane derivatives of hetarylphenols and hetarylanilines of the formula where R1 is hydrogen or alkyl of 1 to 4 carbon atoms, R2 is hydrogen, halogen, alkyl of 1 to 4 carbon atoms or alkoxy where alkyl is of 1 to 3 carbon atoms, the phenyl ring can be monosubstituted or disubstituted by R2, X is oxygen or an NH group, and the heterocyclic structure Het. is 1,3,4-oxadiazolyl, triazolyl, imidazolyl or pyrazolyl, and their physiologically tolerated addition salts with acids, processes for their preparation, and pharmaceutical formulations which contain these compounds and exhibit predominantly sedative, neuroleptic and hypotensive properties.

公开(公告)号：DK19082A

公开(公告)日：1982-07-20

申请号：DK19082

申请日：1982-01-18

Applicant: BASF AG

Inventor： FRANKE A ,  STEINER G ,  THIEME P C ,  LENKE D ,  GRIES J ,  TESCHENDORF H J

IPC: C07D249/08 ,  A61K31/41 ,  A61K31/415 ,  A61K31/42 ,  A61K31/495 ,  A61K31/496 ,  A61K31/505 ,  A61P9/02 ,  A61P11/08 ,  A61P25/08 ,  A61P25/20 ,  C07D231/12 ,  C07D231/38 ,  C07D233/60 ,  C07D233/88 ,  C07D239/42 ,  C07D261/08 ,  C07D295/06 ,  C07D295/092 ,  C07D521/00 ,  C07D

Abstract: Novel (hetarylphenoxy)-(phenylpiperazinyl)-propanols of the formula I where R1 is hydrogen, amino or alkyl of 1 to 4 carbon atoms, R2 is hydrogen, halogen, alkyl of 1 to 4 carbon atoms or alkoxy where alkyl is of 1 to 3 carbon atoms, the phenyl ring can be monosubstituted or disubstituted by R2, and the heterocyclic structure Het. is pyrimidinyl, triazol-1-yl, imidazol-1-yl, pyrazol-3-yl or isoxazol-3-yl, and their physiologically tolerated addition salts with acids, processes for their preparation, and pharmaceutical formulations which contain these compounds and exhibit predominantly hypotensive, sedative, neuroleptic and broncholytic properties.

公开(公告)号：DK188680A

公开(公告)日：1980-11-11

申请号：DK188680

申请日：1980-04-30

Applicant: BASF AG

Inventor： STEINER G ,  FRANKE A ,  LENKE D ,  TESCHENDORF H J ,  WORSTMANN W ,  KREISKOTT H

IPC: A61K31/55 ,  A61P25/18 ,  C07D223/20 ,  C07D401/06 ,  C07D403/04 ,  C07D

Abstract: 6-Substituted 11-alkylene-morphanthridines, also referred to as 11-alkylene-dibenzo[b,e]-azepines, their pure cis- and trans-isomers, processes for their preparation, and therapeutic agents containing these compounds, which may be used as drugs, in particular neuroleptics, sedatives, hypnotics, analgesics, antidepressants or agents for treating Parkinson's syndrome.