公开(公告)号：DE2261637A1

公开(公告)日：1974-06-20

申请号：DE2261637

申请日：1972-12-16

Applicant: BASF AG

Inventor： THIELE UEW DR ,  KOENIG HORST DR ,  EICKEN KARL DR ,  GIERTZ HUBERT PROF DR ,  HAUPT INGRID DR

IPC: A61K31/045 ,  A61K31/135 ,  C07C35/44 ,  C07D295/00 ,  C07C87/40 ,  A61K27/00 ,  C07D27/04 ,  C07D49/34

Abstract: Novel title cpds. (and salts) are of formula (I):- (R1 and R2 are each opt. acylated OH or NR3R4; R3 and R4 are H, opt. substd. alkyl, cycloalkyl or aralkyl; or R3 and R4 together complete a heterocycle; or R1 and R2 are -N(R5).CO.N(R6) or -O.CO.O-, R5 and R6 are alkyl). Specifically claimed are (I) with R1 and R2 = MeNH, Me2N or pyrrolidino or R1 + R2 = -N(CH3).CO.N(CH3)-. Prepn. is by catalytic redn. of (II) opt. in presence of HNR3R4; or when R1=R2=H, photochemical redn. of (II) in an H-donating solvent. (I) are useful as antiparinsonian, sedative, anticonvulsant, spasmolytic, analgesic, diuretic, antiinflammatory as viricidal agents.