公开(公告)号：BR9907308A

公开(公告)日：2000-12-19

申请号：BR9907308

申请日：1999-06-04

Applicant: BASF AG

Inventor： SCHUHMACHER PETER ,  SCHNEIDER NORBERT ,  WESTENFELDER HORTS ,  HAREMZA SYLKE ,  HABECK THORSTEN ,  MEYER FRANK

IPC: A61K8/00 ,  A61K8/02 ,  A61K8/23 ,  A61K8/25 ,  A61K8/29 ,  A61K8/31 ,  A61K8/33 ,  A61K8/34 ,  A61K8/36 ,  A61K8/37 ,  A61K8/41 ,  A61K8/46 ,  A61K8/49 ,  A61K8/73 ,  A61K8/86 ,  A61K8/89 ,  A61K8/97 ,  A61K8/98 ,  A61K31/255 ,  A61K31/34 ,  A61P17/16 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q1/10 ,  A61Q5/00 ,  A61Q17/04 ,  A61Q19/00 ,  C09B67/20 ,  C09C3/08 ,  C09K3/00 ,  A61K7/40

Abstract: Liquid crystal compositions forming a cholesteric phase with a pitch of less than 450 nm, comprising either at least one polymerizable chiral liquid crystal monomer or a mixture of at least one polymerizable achiral liquid crystal monomer and at least one chiral additive, are used as ultraviolet filters for protecting skin or hair against solar radiation. Liquid crystal compositions forming a cholesteric phase with a pitch of less than 450 nm, comprising either: (a) at least one polymerizable chiral liquid crystal monomer of formula (I); or (b) a mixture of at least one polymerizable achiral liquid crystal monomer of formula (II) and at least one chiral additive, are used as ultraviolet (UV) filters in cosmetic and pharmaceutical compositions for protecting human skin or hair against solar radiation: A -A = spacers with a chain length of 1-30C; Y -Y = bonds, O, S, C(O)O, OC(O), CH=CHC(O)O, OC(O)O, C(O)N(R), N(R)C(O), CH2O, OCH2, CH=N, N=CH or N=N; M , M = mesogenic groups; R = H or 1-4C alkyl; Z = H, 1-4C alkyl or a polymerizable group, at least one being a polymerizable group; Z , Z = H, 1-4C alkyl or polymerizable groups, at least one being a polymerizable group; X = an n-valent chiral group; m, o, p = 0 or 1; n = 1-6. Independent claims are also included: (1) use of the liquid crystal compositions as photostable UV reflectors; (2) use of the liquid crystal compositions as UV stabilizers in cosmetic and pharmaceutical formulations; (3) pigments containing the polymerized liquid crystal compositions.