公开(公告)号：US20250019328A1

公开(公告)日：2025-01-16

申请号：US18576314

申请日：2022-05-10

Applicant: BASF SE

Inventor： Thomas Schaub ,  Steffen Mader ,  Alois Kindler ,  A.Stephen K. Hashmi ,  Daniel James Tindall

IPC: C07C29/143 ,  B01J23/46 ,  B01J31/24 ,  B01J38/60 ,  C07C29/86

Abstract: A process for the preparation of L-lditol comprising at least the process steps: i) a L-Sorbose comprising composition is subjected to hydrogenation with hydrogen in the presence of a hydrophobic stereoselective ruthenium catalyst complex in a homogeneous solution, wherein the ruthenium catalyst complex comprises at least one chiral ligand containing at least two phosphorus atom, which are capable of coordinating to the ruthenium yielding in a composition comprising L-lditol as the main product; ii) separation of the reaction products produced in step i) from the ruthenium catalyst complex; iii) reactivating the separated ruthenium catalyst complex of step ii) by adding a chloride source and reusing the reactivated ruthenium catalyst complex in step i).