公开(公告)号：US20250019328A1

公开(公告)日：2025-01-16

申请号：US18576314

申请日：2022-05-10

Applicant: BASF SE

Inventor： Thomas Schaub ,  Steffen Mader ,  Alois Kindler ,  A.Stephen K. Hashmi ,  Daniel James Tindall

IPC: C07C29/143 ,  B01J23/46 ,  B01J31/24 ,  B01J38/60 ,  C07C29/86

Abstract: A process for the preparation of L-lditol comprising at least the process steps: i) a L-Sorbose comprising composition is subjected to hydrogenation with hydrogen in the presence of a hydrophobic stereoselective ruthenium catalyst complex in a homogeneous solution, wherein the ruthenium catalyst complex comprises at least one chiral ligand containing at least two phosphorus atom, which are capable of coordinating to the ruthenium yielding in a composition comprising L-lditol as the main product; ii) separation of the reaction products produced in step i) from the ruthenium catalyst complex; iii) reactivating the separated ruthenium catalyst complex of step ii) by adding a chloride source and reusing the reactivated ruthenium catalyst complex in step i).

公开(公告)号：US20230143448A1

公开(公告)日：2023-05-11

申请号：US17918634

申请日：2021-04-13

Applicant: BASF SE

Inventor： Thomas Schaub ,  Alois Kindler ,  Steffen Mader ,  A. Stephen K. Hashmi ,  Daniel James Tindall

IPC: C07C29/145 ,  B01J31/24

CPC classification number: C07C29/145 ,  B01J31/2452 ,  C07B2200/07 ,  B01J2231/641 ,  B01J2531/821

Abstract: The invention relates to a process for L-Iditol by hydrogenating L-Sorbose. Further, the invention also relates to a use of a transition metal complex as hydrogenation catalyst for L-Sorbose. The invention relates to a process for the preparation of L-Iditol comprising at least one reaction step, in which a composition comprising L-Sorbose and hydrogen is reacted in the presence of a transition metal catalyst complex in a homogeneous solution, wherein the transition metal catalyst complex comprises at least one chiral ligand containing at least one phosphorus atom, which is capable of coordinating to the transition metal, and wherein the transition metal is selected from metals of groups 8, 9 and 10 of the periodic table of the elements according to IUPAC. The invention further relates to a use of a transition metal complex as defined above and below as hydrogenation catalyst for compositions comprising L-Iditol or mixtures thereof.