公开(公告)号：US09260402B2

公开(公告)日：2016-02-16

申请号：US14302046

申请日：2014-06-11

Applicant: BASF SE

Inventor： Benoit Blank ,  Alois Kindler ,  Peter Bassler ,  Markus Piepenbrink ,  Ortmund Lang ,  Carmen Feldner

IPC: C07D307/46 ,  C07D307/48 ,  B01D3/00

CPC classification number: C07D307/46 ,  B01D3/009 ,  C07D307/48 ,  Y02P20/127

Abstract: A process is described for the preparation of 5-hydroxymethylfurfural (HMF), which comprises the following steps: provision or preparation of a starting mixture, comprising one, two or more starting compounds selected from the group consisting of hexoses, oligosaccharides comprising hexose units, and polysaccharides comprising hexose units, one, two or more organic salts with a melting point 200° C. at 1013.25 hPa, optionally additionally one or more catalysts for the conversion of the one starting compound or at least one of the two or more starting compounds to 5-hydroxymethylfurfural (HMF), optionally water, optionally further substances, adjustment of reaction conditions such that an amount of the starting compound or starting compounds converts to HMF.

Abstract translation: 描述了用于制备5-羟甲基糠醛（HMF）的方法，其包括以下步骤：提供或制备起始混合物，其包含一种，两种或更多种选自己糖，包含己糖单元的寡糖， 和多糖，其包含己糖单元，一种，两种或更多种在1013.25hPa的熔点<180℃和沸点> 200℃的有机盐，任选地另外一种或多种用于转化一种起始化合物的催化剂或 两种或更多种起始化合物中的至少一种至5-羟甲基糠醛（HMF），任选的水，任选的其它物质，调节反应条件使得起始化合物或起始化合物的量转化为HMF。

公开(公告)号：US20140371473A1

公开(公告)日：2014-12-18

申请号：US14302046

申请日：2014-06-11

Applicant: BASF SE

Inventor： Benoit Blank ,  Alois Kindler ,  Peter Bassler ,  Markus Piepenbrink ,  Ortmund Lang ,  Carmen Feldner

IPC: C07D307/46 ,  B01D3/00

CPC classification number: C07D307/46 ,  B01D3/009 ,  C07D307/48 ,  Y02P20/127

Abstract: A process is described for the preparation of 5-hydroxymethylfurfural (HMF), which comprises the following steps: provision or preparation of a starting mixture, comprising one, two or more starting compounds selected from the group consisting of hexoses, oligosaccharides comprising hexose units, and polysaccharides comprising hexose units, one, two or more organic salts with a melting point 200° C. at 1013.25 hPa, optionally additionally one or more catalysts for the conversion of the one starting compound or at least one of the two or more starting compounds to 5-hydroxymethylfurfural (HMF), optionally water, optionally further substances, adjustment of reaction conditions such that an amount of the starting compound or starting compounds converts to HMF.

Abstract translation: 描述了用于制备5-羟甲基糠醛（HMF）的方法，其包括以下步骤：提供或制备起始混合物，其包含一种，两种或更多种选自己糖，包含己糖单元的寡糖， 和多糖，其包含己糖单元，一种，两种或更多种在1013.25hPa的熔点<180℃和沸点> 200℃的有机盐，任选地另外一种或多种用于转化一种起始化合物的催化剂或 两种或更多种起始化合物中的至少一种至5-羟甲基糠醛（HMF），任选的水，任选的其它物质，调节反应条件使得起始化合物或起始化合物的量转化为HMF。

公开(公告)号：US09169227B2

公开(公告)日：2015-10-27

申请号：US13711717

申请日：2012-12-12

Applicant: BASF SE

Inventor： René Backes ,  Benoit Blank ,  Alois Kindler ,  Carmen Feldner

IPC: C07D307/48 ,  C07D307/46

CPC classification number: C07D307/48 ,  C07D307/46

Abstract: Method for producing 5-hydroxymethylfurfural (HMF), wherein a) solutions (hereinbelow called starting solution) which comprise a hexose and an organic solvent with a boiling point greater than 200° C. (at standard pressure) (for short called high-boiling component), and steam are fed to a reaction vessel, b) in the reaction vessel, a conversion of the hexose to HMF takes place in the presence of steam with the simultaneous distillative removal of the HMF and c) as distillate, an aqueous, HMF-comprising solution (hereinbelow called distillate) is obtained.

Abstract translation: 制备5-羟甲基糠醛（HMF）的方法，其中a）包含己糖和沸点大于200℃的有机溶剂（在标准压力下）（简称为高沸点）的溶液（以下称为起始溶液） 并且蒸汽进料到反应容器中，b）在反应容器中，己糖到HMF的转化在蒸汽存在下进行，同时蒸馏除去HMF，和c）作为馏出物，水， 获得含HMF的溶液（以下称为馏出物）。

公开(公告)号：US20130345450A1

公开(公告)日：2013-12-26

申请号：US13711810

申请日：2012-12-12

Applicant: BASF SE

Inventor： Ralf Böhling ,  Benoit Blank ,  Alois Kindler ,  Carmen Feldner ,  Sandra Umlauf

IPC: C07D307/46 ,  C07D307/68

CPC classification number: C07D307/46 ,  C07D307/68

Abstract: Method for producing solutions which comprise 5-hydroxymethylfurfural (HMF) and have a reduced content of starting materials of the HMF synthesis or a reduced content of by-products of the HMF synthesis (hereinbelow called product solution), which comprises treating solutions which comprise HMF starting materials or by-products of the HMF synthesis and an organic solvent having at least two ether groups (for short polyether) (hereinbelow called starting solution) in an evaporator with steam.

Abstract translation: 制备包含5-羟甲基糠醛（HMF）并且具有降低的HMF合成原料含量或HMF合成副产物含量（以下称为产品溶液）的溶液的方法，其包括处理包含HMF的溶液 在具有蒸汽的蒸发器中，HMF合成的原料或副产物和具有至少两个醚基团（短聚醚）的有机溶剂（以下称为起始溶液）。

公开(公告)号：US09162998B2

公开(公告)日：2015-10-20

申请号：US13712056

申请日：2012-12-12

Applicant: BASF SE

Inventor： René Backes ,  Benoit Blank ,  Alois Kindler ,  Carmen Feldner

IPC: C07D307/46

CPC classification number: C07D307/46 ,  Y02P20/127

Abstract: A process for preparing 5-hydroxymethylfurfural (HMF), which comprises a) feeding solutions (hereinafter called starting solution) comprising one or more saccharides and an organic solvent having a boiling point greater than 200° C. (at standard pressure) (called high boiler for short) and water,  and a solvent having a boiling point greater than 60° C. and less than 200° C. (at standard pressure, called low boiler for short) to a reaction vessel, b) effecting a conversion of hexose to HMF in the reaction vessel in the presence of water vapor with simultaneous distillative removal of the HMF and c) obtaining, as the distillate, an aqueous, HMF-comprising solution (hereinafter called distillate).

Abstract translation: 一种制备5-羟甲基糠醛（HMF）的方法，其包括a）将包含一种或多种糖和沸点大于200℃的有机溶剂（在标准压力下）（称为高浓度）的进料溶液（以下称为起始溶液） 锅炉）和水，以及沸点大于60℃且小于200℃（在标准压力下简称为低锅炉）的溶剂，b）进行己糖转化 在水蒸汽存在下在反应容器中的HMF，同时蒸馏除去HMF，和c）获得作为馏出物的含水HMF溶液（以下称为馏出物）。

公开(公告)号：US20130150597A1

公开(公告)日：2013-06-13

申请号：US13712056

申请日：2012-12-12

Applicant: BASF SE

Inventor： René Backes ,  Benoit Blank ,  Alois Kindler ,  Carmen Feldner

IPC: C07D307/46

CPC classification number: C07D307/46 ,  Y02P20/127

Abstract: A process for preparing 5-hydroxymethylfurfural (HMF), which comprises a) feeding solutions (hereinafter called starting solution) comprising one or more saccharides and an organic solvent having a boiling point greater than 200° C. (at standard pressure) (called high boiler for short) and water,  and a solvent having a boiling point greater than 60° C. and less than 200° C. (at standard pressure, called low boiler for short) to a reaction vessel, b) effecting a conversion of hexose to HMF in the reaction vessel in the presence of water vapor with simultaneous distillative removal of the HMF and c) obtaining, as the distillate, an aqueous, HMF-comprising solution (hereinafter called distillate).

Abstract translation: 一种制备5-羟甲基糠醛（HMF）的方法，其包括a）将包含一种或多种糖和沸点大于200℃的有机溶剂（在标准压力下）（称为高浓度）的进料溶液（以下称为起始溶液） 锅炉）和水，以及沸点大于60℃且小于200℃（在标准压力下简称为低锅炉）的溶剂，b）进行己糖转化 在水蒸汽存在下在反应容器中的HMF，同时蒸馏除去HMF，和c）获得作为馏出物的含水HMF溶液（以下称为馏出物）。

公开(公告)号：US09156802B2

公开(公告)日：2015-10-13

申请号：US13711810

申请日：2012-12-12

Applicant: BASF SE

Inventor： Ralf Böhling ,  Benoit Blank ,  Alois Kindler ,  Carmen Feldner ,  Sandra Umlauf

IPC: C07D307/46 ,  C07D307/68

CPC classification number: C07D307/46 ,  C07D307/68

Abstract: Method for producing solutions which comprise 5-hydroxymethylfurfural (HMF) and have a reduced content of starting materials of the HMF synthesis or a reduced content of by-products of the HMF synthesis (hereinbelow called product solution), which comprises treating solutions which comprise HMF starting materials or by-products of the HMF synthesis and an organic solvent having at least two ether groups (for short polyether) (hereinbelow called starting solution) in an evaporator with steam.

Abstract translation: 制备包含5-羟甲基糠醛（HMF）并且具有降低的HMF合成原料含量或HMF合成副产物含量（以下称为产品溶液）的溶液的方法，其包括处理包含HMF的溶液 在具有蒸汽的蒸发器中，HMF合成的原料或副产物和具有至少两个醚基团（短聚醚）的有机溶剂（以下称为起始溶液）。

公开(公告)号：US20130150596A1

公开(公告)日：2013-06-13

申请号：US13711717

申请日：2012-12-12

Applicant: BASF SE

Inventor： René Backes ,  Benoit Blank ,  Alois Kindler ,  Carmen Feldner

IPC: C07D307/48

CPC classification number: C07D307/48 ,  C07D307/46

Abstract: Method for producing 5-hydroxymethylfurfural (HMF), wherein a) solutions (hereinbelow called starting solution) which comprise a hexose and an organic solvent with a boiling point greater than 200° C. (at standard pressure) (for short called high-boiling component), and steam are fed to a reaction vessel, b) in the reaction vessel, a conversion of the hexose to HMF takes place in the presence of steam with the simultaneous distillative removal of the HMF and c) as distillate, an aqueous, HMF-comprising solution (hereinbelow called distillate) is obtained.

Abstract translation: 制备5-羟甲基糠醛（HMF）的方法，其中a）包含己糖和沸点大于200℃的有机溶剂（在标准压力下）（简称为高沸点）的溶液（以下称为起始溶液） 并且蒸汽进料到反应容器中，b）在反应容器中，己糖到HMF的转化在蒸汽存在下进行，同时蒸馏除去HMF，和c）作为馏出物，水， 获得含HMF的溶液（以下称为馏出物）。