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    UV FILTER COMBINATIONS COMPRISING BENZYLIDENE MALONATES
    2.
    发明申请
    UV FILTER COMBINATIONS COMPRISING BENZYLIDENE MALONATES 审中-公开
    包含苯甲酸二甲酯的UV过滤器组合

    公开(公告)号：WO2011003774A3

    公开(公告)日：2011-04-21

    申请号：PCT/EP2010059181

    申请日：2010-06-29

    Applicant: BASF SE ,  GRUMELARD JULIE ,  EHLIS THOMAS ,  HANSCH MARKUS ,  SOHN MYRIAM

    Inventor： GRUMELARD JULIE ,  EHLIS THOMAS ,  HANSCH MARKUS ,  SOHN MYRIAM

    IPC: A61K8/29 ,  A61K8/35 ,  A61K8/37 ,  A61K8/40 ,  A61K8/41 ,  A61K8/49 ,  A61K8/58 ,  A61Q17/04

    CPC classification number: A61Q17/04 ,  A61K8/37

    Abstract: Disclosed is the use of a UV filter combination, comprising (a) a first UV filter selected from benzylidene malonates of formula (1), wherein R1 methyl; ethyl; propyl; or n-butyl; if R1 is methyl, then R is tert. butyl; formula (II); formula (III); a radical of formula (1a); or a radical of formula (1b); wherein R2 and R3, independently from each other are hydrogen; or methyl; R4 is methyl; ethyl; or n-propyl; R5 and R6 independently from each other are hydrogen; or C1-C3alkyl; if R1 is ethyl; propyl; or n-butyl, then R is isopropyl; and (b) a second UV filter selected from (b1) Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine; (b2) Butyl Methoxydibenzoylmethane; (b3)Diethylhexyl Butamido Triazone; (b4) Ethylhexyl Triazone; (b5) Diethylamino Hydroxy Benzoyl Hexyl Benzoate; (b6) Ethylhexyl Methoxycinnamate; (b7) Ethylhexyl Salicylate; (b8) Homosalate; (b9) Octocrylene; (b10) micronized Methylene Bis-Benzotriazolyl Tetramethylbutylphenol; (b11) Phenylbenzimidazole Sulfonic Acid; (b12) Titanium Dioxide; (b13) micronized Tris-Biphenyl Triazine; and (b14) micronized (2-{4-[2-(4-Diethylamino-2-hydroxy-benzoyl)-benzoyl]-piperazine-1-carbonyl}-phenyl)-(4-diethylamino-2-hydroxy-phenyl)-methanone; (b15) benzoicacid,4,4-[[3-[1,3,3,3-tetramethyl-1-[trimethylsilyl)oxy]-1-disiloxanyl]propyl]amino]-1,3,5-triazine-2,4-diyl]diimino]bis-, dibutyl ester wherein the UV filter combination comprises at least 2 UV filters of component (b1)-(b14); for the protection of human and animal hair and skin against UV radiation.

    Abstract translation: 公开了UV过滤剂组合的用途，其包含（a）选自式（1）的亚甲基丙二酸酯的第一UV过滤剂，其中R 1甲基; 乙基; 丙基; 或正丁基; 如果R1是甲基，则R是叔。 丁基; 公式（II）; 公式（III）; 式（1a）的基团; 或式（1b）的基团; 其中R 2和R 3彼此独立地为氢; 或甲基; R4是甲基; 乙基; 或正丙基​​; R5和R6彼此独立地为氢; 或C 1 -C 3烷基; 如果R1是乙基; 丙基; 或正丁基，则R是异丙基; 和（b）选自（b1）双 - 乙基己氧基苯酚甲氧基苯基三嗪的第二UV过滤剂; （b2）丁基甲氧基二苯甲酰基甲烷; （b3）二乙基己基丁酰氨基三嗪酮; （b4）乙基己基三嗪酮; （b5）二乙氨基羟苯甲酰基苯甲酸己酯; （b6）甲氧基肉桂酸乙基己酯; （b7）水杨酸乙基己酯; （b8）胡莫柳油; （b9）奥克立林; （b10）微粉化的亚甲基双 - 苯并三唑基四甲基丁基苯酚; （b11）苯基苯并咪唑磺酸; （b12）二氧化钛; （b13）微粉化的三联苯三嗪; 和（b14）微粉化（2- {4- [2-（4-二乙基氨基-2-羟基 - 苯甲酰基） - 苯甲酰基] - 哌嗪-1-羰基} - 苯基） - （4-二乙基氨基-2-羟基 - 苯基） - 甲酮; （b15）苯甲酸，4,4 - [[3- [1,3,3,3-四甲基-1- [三甲基甲硅烷基]氧基] -1-二硅氧烷基]丙基]氨基] -1,3,5-三嗪-2 （b1） - （b14）的至少2个紫外线过滤剂;其中所述紫外线过滤剂组合物包含至少2种组分（b1） - （b14）的紫外线过滤剂; 用于保护人类和动物毛发和皮肤免受紫外线辐射。

    Método de preparação de uma composição, e, composição
    3.
    发明专利
    Método de preparação de uma composição, e, composição 未知

    公开(公告)号：BRPI0820644B1

    公开(公告)日：2022-06-14

    申请号：BRPI0820644

    申请日：2008-11-20

    Applicant: BASF SE

    Inventor： THOMAS EHLIS ,  GRUMELARD JULIE ,  MONGIAT SÉBASTIEN

    IPC: A61K8/49 ,  A61K8/35 ,  A61Q17/04

    Abstract: método de preparação de uma composição, e, composição método para preparar uma composição, que compreende (a) um absorvedor a moagem do absorvedor de uv orgânico insolúvel micronizado, cujo método compreende a moagem do absorvedor de uv orgânico insolúvel, em forma de partículas grossas, em um aparelho de moagem, na presença de um auxiliar de moagem selecionado a partir dos grupos: (b1)ácidos carboxílicos e os seus sais; (b2)ésteres de ácido graxo; (b3)alquil fosfatos ou ésteres de ácido fosfórico; (b4)ácidos carboxílicos etoxilados ou ésteres de polietileno glicol (peg); (b5)éteres de álcool graxo polietileno glicol (peg) de alcoóis graxos; (b6)éteres de polietileno/ polipropileno- glicol de graxos c4-28 insaturados; (b7)alquilfenóis etoxilados ou éteres de alquilfenila etoxilados; (b8)ésteres de poliol e mono-, di- ou tri-glicerídeos; (b9)ésteres de ácidos graxos e sacarose; (b10)mono- e di-ésteres de sorbitano de ácidos graxos c6-c22 saturados e/ ou insaturados e grupos de óxido de etileno; e (b11)tensoativos, que atuam principalmente como agentes de limpeza ou detergentes.

    Modificaciones cristalinas de colorantes de transmisión
    5.
    发明专利
    Modificaciones cristalinas de colorantes de transmisión 未知

    公开(公告)号：ES2603878T3

    公开(公告)日：2017-03-01

    申请号：ES08736607

    申请日：2008-04-28

    Applicant: BASF SE

    Inventor： VOGT MARTIN ,  MÜLLER STEFAN ,  GRUMELARD JULIE ,  DESHAYES CYRILLE ,  PAUL HOLGER ,  HAASE JÜRG ,  EHLIS THOMAS

    IPC: A61Q17/04 ,  A61K8/04 ,  A61K8/49 ,  A61K31/495 ,  C07D295/192

    Abstract: Dispersión acuosa para su uso en la protección de la piel humana frente al oscurecimiento y envejecimiento de la piel, en la que la dispersión acuosa comprende (a) un derivado de benzofenona orgánico moderadamente soluble micronizado de fórmula (1)**Fórmula** que corresponde a la modificación cristalina (C), en el que la modificación cristalina (C) se caracteriza por un patrón de difracción de rayos X de polvo obtenido mediante difracción de rayos X con una muestra en polvo a temperatura ambiente con rayos K de Cu [l(Ka de Cu) >= 1,5425 A] representado por los espaciados d entre planos de la red cristalina:**Tabla** (b) un agente dispersante seleccionado de tensioactivos aniónicos, no iónicos y anfóteros.

    10.
    发明专利
    未知

    公开(公告)号：BRPI0810776A2

    公开(公告)日：2014-10-07

    申请号：BRPI0810776

    申请日：2008-04-28

    Applicant: BASF SE

    Inventor： VOGT MARTIN ,  MUELLER STEFAN ,  GRUMELARD JULIE ,  DESHAYES CYRILLE ,  PAUL HOLGER ,  HAASE JUERG ,  EHLIS THOMAS

    IPC: A61K8/49 ,  A61Q17/04 ,  A61Q19/08

    Abstract: Disclosed is the use of an aqueous dispersion comprising (a) a micronized sparingly soluble organic benzophenone derivative of formula (1), selected from the crystal modifications (B) and (C), wherein the crystal modification (B) is characterized by a peak in the X-ray diffraction pattern at a d-spacing of about 7.70; and wherein the crystal modification (C) is characterized by a peak in the X-ray diffraction pattern at a d-spacing of about 7.06; and (b) a dispersing agent selected from anionic, non-ionic and amphoteric surfactants; for protecting the human skin from browning and skin aging. The new crystal modification (C) represents a thermodynamically stable compound of formula (1) at 25° C. This modification is therefore suitable in dispersions comprising micro-fine particles.

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