公开(公告)号：WO2022157323A1

公开(公告)日：2022-07-28

申请号：PCT/EP2022/051368

申请日：2022-01-21

Applicant: BASF SE

Inventor： KORADIN, Christopher ,  MCLAUGHLIN, Martin John ,  GOETZ, Roland ,  KADUSKAR, Rahul ,  SHINDE, Harish

IPC: C07D495/04

Abstract: The present invention relates to a method for preparing an enantiomerically enriched form of 3-(2-chlorothiazol-5-yl)-8-methyl-7-oxo-6-phenyl-2,3-dihydrothiazolo[3,2-a]pyrimidin-4-ium-5-olate.

公开(公告)号：WO2022157324A1

公开(公告)日：2022-07-28

申请号：PCT/EP2022/051369

申请日：2022-01-21

Applicant: BASF SE

Inventor： KORADIN, Christopher ,  MCLAUGHLIN, Martin John ,  GOETZ, Roland ,  KADUSKAR, Rahul ,  SHINDE, Harish ,  GARIVET, Guillaume Michel Jacques

IPC: C07D239/68 ,  C07D417/12

Abstract: The present invention relates to a method for preparing 2-[2-(2-chlorothiazol-5-yl)-2- oxo-ethyl]sulfanyl-6-hydroxy-3-methyl-5-phenyl-pyrimidin-4-one or a tautomer thereof, to 2-[2-(2-chlorothiazol-5-yl)-2-oxo-ethyl]sulfanyl-6-hydroxy-3-methyl-5-phenyl- pyrimidin-4-one or a tautomer thereof and to its use as intermediate in the preparation of 2,3-dihydrothiazolo[3,2-a]pyrimidinium compounds, and specifically of 3-(2- chlorothiazol-5-yl)-8-methyl-7-oxo-6-phenyl-2,3-dihydrothiazolo[3,2-a]pyrimidin-4-ium- 5-olate and enantiomerically enriched forms thereof.

公开(公告)号：WO2021204774A1

公开(公告)日：2021-10-14

申请号：PCT/EP2021/058892

申请日：2021-04-06

Applicant: BASF SE

Inventor： BORATE, Kailaskumar ,  THIRUNAVUKKARASU, Saravanan ,  KADUSKAR, Rahul ,  SHINDE, Harish ,  GOETZ, Roland

IPC: C07C209/10 ,  C07C211/52

Abstract: The presently claimed invention relates to a process for the preparation of di-, tri-, or tetra fluoroarylamine by reacting polyfluorinated aryl chlorides with ammonia in the presence of a base, a metal catalyst and a ligand. Di-, tri-, tetrafluoroarylamines are valuable intermediates and find application in several areas, mainly in epoxy polymers, colorants, dyes, polyurethanes, agrochemicals and pharmaceutical active agents.

公开(公告)号：WO2023030916A1

公开(公告)日：2023-03-09

申请号：PCT/EP2022/073140

申请日：2022-08-19

Applicant: BASF SE

Inventor： KADUSKAR, Rahul ,  VIERTELHAUS, Martin ,  KOLSE, Sunil ,  PETKOVA, Desislava Slavcheva ,  SEISER, Tobias ,  GOETZ, Roland ,  SHINDE, Harish ,  URCH, Henning ,  PAVON ROMERO, Ricardo Hugo

IPC: C07D239/54 ,  A01N43/54

Abstract: The present invention relates to one crystalline form A of methyl 2-[2-[2-bromo-4-fluoro-5-[3- methyl-2,6-dioxo-4-(trifluoromethyl)pyrimidin-1-yl]phenoxy]phenoxy]-2-methoxy-acetate, a process for the production of this crystalline form and formulations for plant protection comprising such form A.

公开(公告)号：WO2022069462A1

公开(公告)日：2022-04-07

申请号：PCT/EP2021/076624

申请日：2021-09-28

Applicant: BASF SE

Inventor： KORADIN, Christopher ,  SHINDE, Harish ,  MCLAUGHLIN, Martin John ,  KADUSKAR, Rahul ,  STAEHLE, Philipp M ,  GOETZ, Roland ,  KHAMKAR, Sunil

IPC: C07D277/32

Abstract: The present invention relates to a process for the preparation 2-chloro-1-(2-chlorothiazol-5-yl)ethanone.

公开(公告)号：WO2022200594A1

公开(公告)日：2022-09-29

申请号：PCT/EP2022/057968

申请日：2022-03-25

Applicant: BASF SE

Inventor： MCLAUGHLIN, Martin John ,  KORADIN, Christopher ,  KADUSKAR, Rahul ,  SHINDE, Harish ,  GOETZ, Roland

IPC: C07D417/12 ,  A01N43/78

Abstract: The present invention relates to a method for preparing an enantiomerically enriched form of 2-[2-(2-chlorothiazol-5-yl)-2- hydroxy-ethyl]sulfanyl-6-hydroxy-3-methyl-5-phenyl-pyrimidin-4-one of the formula (I) by hydrogenation of 2-[2-(2-chlorothiazol-5-yl)-2-oxo-ethyl]sulfanyl-6- hydroxy-3-methyl-5-phenyl-pyrimidin-4-one (1) in the presence of a chiral transition metal catalyst.

公开(公告)号：WO2022157321A1

公开(公告)日：2022-07-28

申请号：PCT/EP2022/051362

申请日：2022-01-21

Applicant: BASF SE

Inventor： KORADIN, Christopher ,  MCLAUGHLIN, Martin John ,  SHINDE, Harish ,  KADUSKAR, Rahul ,  GOETZ, Roland ,  GARIVET, Guillaume Michel Jacques

IPC: C07D495/04

Abstract: The present invention relates to a method for preparing an enantiomerically enriched form of 3-(2-chlorothiazol-5-yl)-8-methyl-7-oxo-6-phenyl-2,3-dihydrothiazolo[3,2-a]pyrimidin-4-ium-5-olate.

公开(公告)号：WO2022157316A1

公开(公告)日：2022-07-28

申请号：PCT/EP2022/051354

申请日：2022-01-21

Applicant: BASF SE

Inventor： MCLAUGHLIN, Martin John ,  KORADIN, Christopher ,  KADUSKAR, Rahul ,  SHINDE, Harish ,  GOETZ, Roland ,  GARIVET, Guillaume Michel Jacques

IPC: C07D417/12

Abstract: The present invention relates to a method for preparing 2-[2-(2-chlorothiazol-5-yl)-2- hydroxy-ethyl]sulfanyl-6-hydroxy-3-methyl-5-phenyl-pyrimidin-4-one or a tautomer thereof or enantiomerically enriched forms thereof, to 2-[2-(2-chlorothiazol-5-yl)-2- hydroxy-ethyl]sulfanyl-6-hydroxy-3-methyl-5-phenyl-pyrimidin-4-one or a tautomer thereof or enantiomerically enriched forms thereof, and to the use thereof as intermediate in the preparation of 2,3-dihydrothiazolo[3,2-a]pyrimidinium compounds, specifically of 3-(2-chlorothiazol-5-yl)-8-methyl-7-oxo-6-phenyl-2,3-dihydrothiazolo[3,2- a]pyrimidin-4-ium-5-olate and enantiomerically enriched forms thereof.

公开(公告)号：WO2022157106A1

公开(公告)日：2022-07-28

申请号：PCT/EP2022/050851

申请日：2022-01-17

Applicant: BASF SE

Inventor： KADUSKAR, Rahul ,  BORATE, Kailaskumar ,  ADHAV, Suyog ,  THIRUNAVUKKARASU, Saravanan ,  SHINDE, Harish ,  GOETZ, Roland

IPC: C07C231/12 ,  C07D213/00 ,  C07C233/15

Abstract: The presently claimed invention relates to a process for the preparation of mono-, di-, tri-, fluoro arylamide or hetroarylamide.

公开(公告)号：WO2021063880A1

公开(公告)日：2021-04-08

申请号：PCT/EP2020/077090

申请日：2020-09-28

Applicant: BASF SE

Inventor： SHINDE, Harish ,  KADUSKAR, Rahul ,  KORADIN, Christopher ,  MCLAUGHLIN, Martin John ,  GOETZ, Roland ,  KHAMKAR, Sunil

IPC: C07D277/32

Abstract: The present invention relates to a process for the preparation 2-chloro-1-(2-chlorothiazol-5-yl)ethanone.