公开(公告)号：AT451452T

公开(公告)日：2009-12-15

申请号：AT07803080

申请日：2007-08-30

Applicant: BASF SE

Inventor： STUERMER RAINER ,  HAUER BERNHARD ,  ROSCHE BETTINA ,  MUELLER ANDRE

IPC: C12N9/02 ,  C07C5/09 ,  C12P7/00

Abstract: Producing alkenones (I) comprises reducing an alkynone (II) in the presence of an Old Yellow Enzyme having one of six amino acid sequences given in the specification. Producing alkenones of formula (I) comprises reducing an alkynone of formula (II) in the presence of an Old Yellow Enzyme having one of six amino acid sequences given in the specification. R 1>-CH=CH-CO-R 2> (I) R 1>-CC-CO-R 2> (II) R 1>H, 1-6C alkyl, 2-6C alkenyl or an optionally substituted carbocyclic or heterocyclic aromatic or nonaromatic group; R 2>H, 1-6C alkyl or 2-6C alkenyl.

公开(公告)号：DE602006005515D1

公开(公告)日：2009-04-16

申请号：DE602006005515

申请日：2006-11-10

Applicant: BASF SE

Inventor： STUERMER RAINER ,  FRIEDRICH THOMAS ,  MUELLER ANDRE ,  HAUER BERNHARD ,  ROSCHE BETTINA

IPC: C12P7/24

Abstract: The invention relates to a process for the production of optically active Citronellal by enzymatic reduction of Citral with a reductase from Zymomonas mobilis.

公开(公告)号：DE502007002297D1

公开(公告)日：2010-01-21

申请号：DE502007002297

申请日：2007-08-30

Applicant: BASF SE

Inventor： STUERMER RAINER ,  HAUER BERNHARD ,  ROSCHE BETTINA ,  MUELLER ANDRE

IPC: C12N9/02 ,  C07C5/09 ,  C12P7/00

Abstract: Producing alkenones (I) comprises reducing an alkynone (II) in the presence of an Old Yellow Enzyme having one of six amino acid sequences given in the specification. Producing alkenones of formula (I) comprises reducing an alkynone of formula (II) in the presence of an Old Yellow Enzyme having one of six amino acid sequences given in the specification. R 1>-CH=CH-CO-R 2> (I) R 1>-CC-CO-R 2> (II) R 1>H, 1-6C alkyl, 2-6C alkenyl or an optionally substituted carbocyclic or heterocyclic aromatic or nonaromatic group; R 2>H, 1-6C alkyl or 2-6C alkenyl.

公开(公告)号：AT424465T

公开(公告)日：2009-03-15

申请号：AT06829974

申请日：2006-11-10

Applicant: BASF SE

Inventor： STUERMER RAINER ,  FRIEDRICH THOMAS ,  MUELLER ANDRE ,  HAUER BERNHARD ,  ROSCHE BETTINA

IPC: C12P7/24

Abstract: The invention relates to a process for the production of optically active Citronellal by enzymatic reduction of Citral with a reductase from Zymomonas mobilis.

公开(公告)号：ES2336724T3

公开(公告)日：2010-04-15

申请号：ES07803080

申请日：2007-08-30

Applicant: BASF SE

Inventor： STURMER RAINER ,  HAUER BERNHARD ,  ROSCHE BETTINA ,  MUELLER ANDRE

IPC: C12N9/02 ,  C07C5/09 ,  C12P7/00

Abstract: Procedimiento para la obtención enzimática de derivados de alquenona de la fórmula general (2) a partir de derivados de alquinona α,β-insaturados de la fórmula general (1) **(Ver fórmula)** en la que R1 significa H, alquilo con 1 hasta 6 átomos de carbono, alquenilo con 2 hasta 6 átomos de carbono, o un resto aromático o no aromático, carbocíclico o heterocíclico, en caso dado substituido, R2significa H, alquilo con 1 hasta 6 átomos de carbono o alquenilo con 2 hasta 6 átomos de carbono, mediante la reducción de un compuesto de la fórmula (1) en presencia de una reductasa (i) que comprende al menos una de las secuencias de polipéptido SEQ ID NO:1, 2, 3, 5, 7 o 9 o (ii) con una secuencia de polipéptido funcionalmente equivalente, que presenta al menos un 80% de identidad secuencial con SEQ ID NO:1, 2, 3, 5, 7 o 9.