Method for obtaining crystalline 2'-fucosyllactose

    公开(公告)号:AU2019360630B2

    公开(公告)日:2022-10-27

    申请号:AU2019360630

    申请日:2019-10-17

    Applicant: BASF SE

    Abstract: The present invention relates to a method for obtaining crystalline 2'-fucosyllactose from a 2'-FL raw material, which contains 2'-FL as a main constituent and at least 0.5% by weight, frequently at least 1% by weight, in particular at least 2% by weight, more particularly at least 5% by weight, and especially at least 8% by weight,based on the total amount of mono-and oligosaccharides in the raw material, of one or more mono- or oligosaccharides different from 2'-FL, where the method comprises a)providing a solution of the 2'-FL raw material in water, which does not contain more than 10% by weight, preferably not more than 7% by weight, more preferably not more than 5% by weight of organic solvents, based on the total amount of water; b) effecting the crystallization of 2'-FL from the solution provided in step a) by inducing conditions of a controlled super saturation in the solution; and c) separating crystalline 2'-FL from the mother liquor, and where during controlled supersaturation in step b) not more than 10% by weight, preferably not more than 7% by weight, more preferably not more than 5% by weight of organic solvents are present, based on the total amount of water present during step b).

    Method for obtaining crystalline 2'-fucosyllactose

    公开(公告)号:AU2019360630A1

    公开(公告)日:2021-04-29

    申请号:AU2019360630

    申请日:2019-10-17

    Applicant: BASF SE

    Abstract: The present invention relates to a method for obtaining crystalline 2'-fucosyllactose from a 2'-FL raw material, which contains 2'-FL as a main constituent and at least 0.5% by weight, frequently at least 1% by weight, in particular at least 2% by weight, more particularly at least 5% by weight, and especially at least 8% by weight,based on the total amount of mono-and oligosaccharides in the raw material, of one or more mono- or oligosaccharides different from 2'-FL, where the method comprises a)providing a solution of the 2'-FL raw material in water, which does not contain more than 10% by weight, preferably not more than 7% by weight, more preferably not more than 5% by weight of organic solvents, based on the total amount of water; b) effecting the crystallization of 2'-FL from the solution provided in step a) by inducing conditions of a controlled super saturation in the solution; and c) separating crystalline 2'-FL from the mother liquor, and where during controlled supersaturation in step b) not more than 10% by weight, preferably not more than 7% by weight, more preferably not more than 5% by weight of organic solvents are present, based on the total amount of water present during step b).

    Procedimiento de obtención de L-alanina cristalina

    公开(公告)号:ES2688556T3

    公开(公告)日:2018-11-05

    申请号:ES15750357

    申请日:2015-08-07

    Applicant: BASF SE

    Abstract: Procedimiento de obtención de L-alanina cristalina a partir de una solución acuosa de L-alanina que contiene al menos 100 ppm, en base a L-alanina, de uno o más α-aminoácidos diferentes de L-alanina, comprendiendo el procedimiento a) proporcionar una solución acuosa de L-alanina que contiene al menos 100 ppm, en base a L-alanina, de uno o más α-aminoácidos diferentes de L-alanina; b) someter la solución de L-alanina a una cristalización induciendo condiciones de supersaturación controlada de manera tal que la proporción c:c* de la concentración c de L-alanina disuelta a la solubilidad en equilibrio c* de Lalanina bajo las condiciones de supersaturación controlada son de> 1:1 a 1,5:1, lo que afecta la cristalización de Lalanina; y c) separar L-alanina cristalina del licor madre. en el que la solución acuosa de L-alanina se alimenta a un aparato de cristalización operado en continuo, que contiene una suspensión acuosa de cristales de L-alanina.

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