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公开(公告)号:EP0682566A4
公开(公告)日:1998-10-21
申请号:EP94912801
申请日:1994-03-17
Applicant: BAXTER INT
Inventor: BROWN RICHARD I , CERNY DAVID E , DENNEHEY T MICHAEL , PATEL INDRAJIT T , GLASH DEAN M
CPC classification number: B04B5/0442 , B04B2005/045 , B04B2005/0492 , F02B2075/025
Abstract: An umbilicus (24) conveys fluid between a stationary body and a rotating body in a small, compact operating environment. The umbilicus comprises an elongated body (200) including a proximal end, a distal end, and a middle region between the proximal and distal ends. A first support block (204) is attached to the proximal end. A second support block (206) is attached to the distal end. The first support block (204) includes a strain relief sleeve (212). The umbilicus is otherwise free of any other strain relief sleeve. A thrust bearing member (214) in the middle region spaced apart from the strain relief sleeve (212) and the distal end. The umbilicus is otherwise free of any other thrust bearing member. The thrust bearing member (214) has an inner annular body (218), an outer annular body (216) about the inner annular body (218), and an array of ball bearings (220) between the inner and outer annular bodies. The ball bearings (220) support the inner annular body (218) for rotation relative to the outer annular body (216).
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公开(公告)号:EP0301077A4
公开(公告)日:1990-03-12
申请号:EP88902011
申请日:1988-01-29
Applicant: BAXTER INT
Inventor: BROWN RICHARD I , CERNY DAVID E , FOLEY JOHN T , WEST JOSEPH C JR
CPC classification number: B04B5/0442 , A61M2205/15 , B04B5/0428 , B04B2005/045
Abstract: An apparatus and method of separating a component from a collected quantity of fluid. The apparatus (10) includes a dual member centrifuge (12) and an associated fluid flow transfer set (14). The transfer set (14) has a collection container (44) in which a quantity of fluid can be initially accumulated. The collection container (44) is formed as a disk-shaped plastic member with an elongated generally radially extending barrier member formed therein. A component collection container (64) is in fluid flow communication with the disk-shaped container. The method provides for centrifugation of the collection container (44) in the dual member centrifuge (12) thereby separating out the selected fluid component. The component can then be pumped out of the collection container (44) into the component accumulation container (64). The residual fluid can be sealed in the collection container for later use. The component collection container can be separated and sealed also for later use.
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公开(公告)号:EP0299054A4
公开(公告)日:1990-03-12
申请号:EP88901722
申请日:1988-01-29
Applicant: BAXTER INT
Inventor: BROWN RICHARD I , SMITH SIDNEY , CERNY DAVID E , FOLEY JOHN T
IPC: A61K35/14 , A61M1/02 , A61M1/30 , A61M1/36 , B01D17/02 , B01D21/24 , B01D21/26 , B04B5/00 , B04B5/04 , B04B7/08 , B04B11/04 , B04B13/00 , G01D5/347
CPC classification number: B01D17/0217 , A61M1/025 , A61M1/302 , A61M1/303 , A61M1/308 , A61M1/3496 , A61M1/3603 , A61M1/3681 , A61M1/3693 , A61M1/3696 , A61M2202/0427 , A61M2205/331 , A61M2205/3344 , A61M2205/3351 , A61M2205/3355 , A61M2205/3393 , B01D21/2405 , B01D21/245 , B01D21/26 , B01D21/262 , B01D21/34 , B01D2221/10 , B04B5/0442 , B04B7/08 , B04B13/00 , B04B2005/045 , G01D5/34715 , A61M2202/0071
Abstract: The apparatus comprises an elongate, flexible separation chamber (51) receivable in a slot (46) of a rotor, so that rotation of the rotor causes separation of a fluid, supplied through an inlet port (51a) to the chamber (51), in regions (104,106) along opposite walls (50d,50e) of the chamber. Each component is removed through a corresponding outlet port (51b,51c). One of the outlet ports (51c) is arranged adjacent to the inlet port (51a) and a ramp (111) is provided or formed in the chamber (51) to direct flow of the respective component towards that outlet in a direction opposite to the direction of fluid flow through the inlet.
Abstract translation: 该装置包括可接收在转子的槽(46)中的细长的柔性分离室(51),使得转子的旋转导致通过入口(51a)供应到腔室(51)的流体分离, 沿着腔室的相对壁(50d,50e)的区域(104,106)。 通过相应的出口(51b,51c)去除每个部件。 出口(51c)中的一个布置成邻近入口(51a)并且在室(51)中设置或形成斜面(111),以引导相应部件朝向与该 流体流过入口的方向。
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公开(公告)号:DE3856327D1
公开(公告)日:1999-05-27
申请号:DE3856327
申请日:1988-01-29
Applicant: BAXTER INT
Inventor: BROWN RICHARD I , CERNY DAVID E , SMITH SIDNEY , FOLEY JOHN T
IPC: A61K35/14 , A61M1/02 , A61M1/30 , A61M1/36 , B01D17/02 , B01D21/24 , B01D21/26 , B04B5/00 , B04B5/04 , B04B7/08 , B04B11/04 , B04B13/00 , G01D5/347
Abstract: A method of separating a selected component, such as platelets, using a centrifuge, comprises separating the fluid into components in three regions (104,106,198) and conveying fluid into the centrifuge while discharging components from the outer two regions through respective ports (50c,50b). Also during such discharge, the selected component is accumulated in the intermediate region 9108) and, after a predetermined volume of one of the other components has been discharged, discharging the third component through one of the ports (50b).
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公开(公告)号:DE3856327T2
公开(公告)日:1999-08-26
申请号:DE3856327
申请日:1988-01-29
Applicant: BAXTER INT
Inventor: BROWN RICHARD I , CERNY DAVID E , SMITH SIDNEY , FOLEY JOHN T
IPC: A61K35/14 , A61M1/02 , A61M1/30 , A61M1/36 , B01D17/02 , B01D21/24 , B01D21/26 , B04B5/00 , B04B5/04 , B04B7/08 , B04B11/04 , B04B13/00 , G01D5/347
Abstract: A method of separating a selected component, such as platelets, using a centrifuge, comprises separating the fluid into components in three regions (104,106,198) and conveying fluid into the centrifuge while discharging components from the outer two regions through respective ports (50c,50b). Also during such discharge, the selected component is accumulated in the intermediate region 9108) and, after a predetermined volume of one of the other components has been discharged, discharging the third component through one of the ports (50b).
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公开(公告)号:DE3855891T2
公开(公告)日:1997-11-20
申请号:DE3855891
申请日:1988-01-29
Applicant: BAXTER INT
Inventor: BROWN RICHARD I , SMITH SIDNEY , CERNY DAVID E , FOLEY JOHN T
IPC: A61K35/14 , A61M1/02 , A61M1/30 , A61M1/36 , B01D17/02 , B01D21/24 , B01D21/26 , B04B5/00 , B04B5/04 , B04B7/08 , B04B11/04 , B04B13/00 , G01D5/347
Abstract: A method of separating a selected component, such as platelets, using a centrifuge, comprises separating the fluid into components in three regions (104,106,198) and conveying fluid into the centrifuge while discharging components from the outer two regions through respective ports (50c,50b). Also during such discharge, the selected component is accumulated in the intermediate region 9108) and, after a predetermined volume of one of the other components has been discharged, discharging the third component through one of the ports (50b).
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公开(公告)号:DE3855891D1
公开(公告)日:1997-05-28
申请号:DE3855891
申请日:1988-01-29
Applicant: BAXTER INT
Inventor: BROWN RICHARD I , SMITH SIDNEY , CERNY DAVID E , FOLEY JOHN T
IPC: A61K35/14 , A61M1/02 , A61M1/30 , A61M1/36 , B01D17/02 , B01D21/24 , B01D21/26 , B04B5/00 , B04B5/04 , B04B7/08 , B04B11/04 , B04B13/00 , G01D5/347
Abstract: A method of separating a selected component, such as platelets, using a centrifuge, comprises separating the fluid into components in three regions (104,106,198) and conveying fluid into the centrifuge while discharging components from the outer two regions through respective ports (50c,50b). Also during such discharge, the selected component is accumulated in the intermediate region 9108) and, after a predetermined volume of one of the other components has been discharged, discharging the third component through one of the ports (50b).
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公开(公告)号:CA2155639A1
公开(公告)日:1995-06-29
申请号:CA2155639
申请日:1994-03-17
Applicant: BAXTER INT
Inventor: BROWN RICHARD L , CERNY DAVID E , DELLEHEY T MICHAEL , PATEL INDRAJIT T , GLASH DEAN M
Abstract: An umbilicus (24) conveys fluid between a stationary body and a rotating body in a small, compact operating environment. The umbilicus comprises an elongated body (200) including a proximal end, a distal end, and a middle region between the proximal and distal ends. A first support block (204) is attached to the proximal end. A second support block (206) is attached to the distal end. The first support block (204) includes a strain relief sleeve (212). The umbilicus is otherwise free of any other strain relief sleeve. A thrust bearing member (214) in the middle region spaced apart from the strain relief sleeve (212) and the distal end. The umbilicus is otherwise free of any other thrust bearing member. The thrust bearing member (214) has an inner annular body (218), an outer annular body (216) about the inner annular body (218), and an array of ball bearings (220) between the inner and outer annular bodies. The ball bearings (220) support the inner annular body (218) for rotation relative to the outer annular body (216).
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