Abstract:
PROBLEM TO BE SOLVED: To furthermore improve an online system used for blood component collection to collect specific cell components, such as blood platelets, from the whole blood of a donor by using an extracorporeal circulation circuit and to return the remaining components to the donor. SOLUTION: In the system, separates the whole blood is separated into red blood cells and a blood platelet-rich plasma in a first step and the blood platelet rich plasma is separated into a blood platelet concentrate and a blood platelet poor plasma in a second step. The blood platelet concentrate is made to remain in a second-step separator and part of the blood platelet poor plasma is held in the system. The balance is returned together with the red blood cells to the donor. The held blood platelet poor plasma is used for resuspension of the blood platelet concentrate.
Abstract:
PROBLEM TO BE SOLVED: To provide a system for obtaining a platelet-rich concentrate with a reduced number of leukocytes in the on-line separation of blood by extracorporeal circulation. SOLUTION: A separation device for separating complete blood counts into erythrocytes and a platelet suspension, a filtering device for reducing the number of leukocytes in the platelet suspension, and another separation device for separating the platelet suspension into the platelet-rich concentrate with a reduced number of leukocytes are arranged in series within a flow passage connectable to the circulatory system of a donor to provide the system controlling the separation process by means of a control device which maintains communication between the flow passage and the donor's circulatory system.
Abstract:
A filtering chamber for a set for the administration of fluids is provided. The chamber includes a housing providing a passageway for the fluid in the administration set. Within the chamber is a filter of screen which filters the fluid flowing through the housing. The filter or screen is attached to the housing during molding of the housing without the use of bonding agents, resulting in a chamber component which may be produced automatically and economically.
Abstract:
An umbilicus (24) conveys fluid between a stationary body and a rotating body in a small, compact operating environment. The umbilicus comprises an elongated body (200) including a proximal end, a distal end, and a middle region between the proximal and distal ends. A first support block (204) is attached to the proximal end. A second support block (206) is attached to the distal end. The first support block (204) includes a strain relief sleeve (212). The umbilicus is otherwise free of any other strain relief sleeve. A thrust bearing member (214) in the middle region spaced apart from the strain relief sleeve (212) and the distal end. The umbilicus is otherwise free of any other thrust bearing member. The thrust bearing member (214) has an inner annular body (218), an outer annular body (216) about the inner annular body (218), and an array of ball bearings (220) between the inner and outer annular bodies. The ball bearings (220) support the inner annular body (218) for rotation relative to the outer annular body (216).
Abstract:
This invention is a bone biopsy needle assembly (10) which includes a handle (11) having a proximal concave curved surface having an off center radius producing a first relatively narrow end, and a second relatively wide end of the handle. A stylet is slidably received within the lumen of the cannula (12).
Abstract:
A blood processing assembly (14) includes a separation element (12) for separating blood from a source into a first component and a second component. The assembly also includes a fluid path (18) that conveys blood between the source and the separation element. The fluid path includes one or more in-line cassettes (22A/B/C) that serve in association with peristaltic pumps to centralize pumping and valving functions of the system. The cassettes also serve to segregate the flow paths of the blood components from each other.
Abstract:
A bone marrow collection kit (10) is provided comprising a collection container for receiving a bone marrow containing fluid (12) having a body (14) that defines an interior (16) and an inlet opening (18) and an outlet opening (28) and including a prefilter (30) that extends from the outlet opening (28) into the interior of the collection container (16) so that fluid must flow through the prefilter (30) to exit the collection container (12) through the outlet opening (28). A first inline filter member (50) is coupled to the outlet opening (28) of the collection container (12), the first inline filter member (50) having a flexible plastic body (60) that defines an interior (66), and an inlet opening (68) and an outlet opening (70) and the interior including a filter (72) so constructed and arranged that fluid that enters the inlet opening (68) must flow through the filter (72) to exit the first inline filter member (50) through the outlet opening (70). A container for receiving a resultant filtered bone marror containing fluid (94) having an interior in fluid communication with the outlet opening (70) of the first inline filter member (50) is also provided.
Abstract:
A filtering chamber for a set for the administration of fluids is provided. The chamber includes a housing providing a passageway for the fluid in the administration set. Within the chamber is a filter of screen which filters the fluid flowing through the housing. The filter or screen is attached to the housing during molding of the housing without the use of bonding agents, resulting in a chamber component which may be produced automatically and economically.
Abstract:
A filtering chamber for a set for the administration of fluids is provided. The chamber includes a housing providing a passageway for the fluid in the administration set. Within the chamber is a filter of screen which filters the fluid flowing through the housing. The filter or screen is attached to the housing during molding of the housing without the use of bonding agents, resulting in a chamber component which may be produced automatically and economically.
Abstract:
A device and method are provided for separating mononuclear cells from red blood cell depleted plasma in a centrifuge blood cell separator. The device includes an inlet (51) for receiving plasma, an area (63) for receiving mononuclear cells, and an outlet (53) for receiving mononuclear cell depleted plasma. The distance and flow path (65) between the inlet (51) and outlet (53) being so constructed and arranged as to cause mononuclear cells to sediment out into the area (61) for receiving the mononuclear cells and causing at least 66 % of the platelets contained in the plasma to flow to and through the outlet.