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公开(公告)号：EP0563364A4
公开(公告)日：1994-08-17
申请号：EP92922369
申请日：1992-10-15
Applicant: BAXTER INT
Inventor： DENNEHEY T MICHAEL , WEST JOSEPH C JR , YANG JAMES W
CPC classification number: A61B10/025 , A61B2010/0258 , A61M1/0056
Abstract: A bone marrow collection kit (10) is provided comprising a collection container for receiving a bone marrow containing fluid (12) having a body (14) that defines an interior (16) and an inlet opening (18) and an outlet opening (28) and including a prefilter (30) that extends from the outlet opening (28) into the interior of the collection container (16) so that fluid must flow through the prefilter (30) to exit the collection container (12) through the outlet opening (28). A first inline filter member (50) is coupled to the outlet opening (28) of the collection container (12), the first inline filter member (50) having a flexible plastic body (60) that defines an interior (66), and an inlet opening (68) and an outlet opening (70) and the interior including a filter (72) so constructed and arranged that fluid that enters the inlet opening (68) must flow through the filter (72) to exit the first inline filter member (50) through the outlet opening (70). A container for receiving a resultant filtered bone marror containing fluid (94) having an interior in fluid communication with the outlet opening (70) of the first inline filter member (50) is also provided.
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Patent Agency Ranking
公开(公告)号：EP0301077A4
公开(公告)日：1990-03-12
申请号：EP88902011
申请日：1988-01-29
Applicant: BAXTER INT
Inventor： BROWN RICHARD I , CERNY DAVID E , FOLEY JOHN T , WEST JOSEPH C JR
CPC classification number: B04B5/0442 , A61M2205/15 , B04B5/0428 , B04B2005/045
Abstract: An apparatus and method of separating a component from a collected quantity of fluid. The apparatus (10) includes a dual member centrifuge (12) and an associated fluid flow transfer set (14). The transfer set (14) has a collection container (44) in which a quantity of fluid can be initially accumulated. The collection container (44) is formed as a disk-shaped plastic member with an elongated generally radially extending barrier member formed therein. A component collection container (64) is in fluid flow communication with the disk-shaped container. The method provides for centrifugation of the collection container (44) in the dual member centrifuge (12) thereby separating out the selected fluid component. The component can then be pumped out of the collection container (44) into the component accumulation container (64). The residual fluid can be sealed in the collection container for later use. The component collection container can be separated and sealed also for later use.
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公开(公告)号：CA2063262C
公开(公告)日：1998-06-30
申请号：CA2063262
申请日：1991-04-01
Applicant: BAXTER INT
Inventor： DENNEHEY T MICHAEL , WEST JOSEPH C JR
Abstract: A device and method are provided for separating mononuclear cells from red blood cell depleted plasma in a centrifuge blood cell separator. The device includes an inlet (51) for receiving plasma, an area (63) for receiving mononuclear cells, and an outlet (53) for receiving mononuclear cell depleted plasma. The distance and flow path (65) between the inlet (51) and outlet (53) being so constructed and arranged as to cause mononuclear cells to sediment out into the area (61) for receiving the mononuclear cells and causing at least 66 % of the platelets contained in the plasma to flow to and through the outlet.
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公开(公告)号：CA1334189C
公开(公告)日：1995-01-31
申请号：CA613606
申请日：1989-09-27
Applicant: BAXTER INT
Inventor： DENNEHEY T MICHAEL , WEST JOSEPH C JR
Abstract: A centrifugal processing system and method introduces fluid to be processed into a centrifugation chamber, while directing the fluid away from the region of the chamber where the largest centrifugal (or "G") forces exist. The fluid is also conveyed into the force field as a generally uniform stream having reduced turbulence or being essentially free of turbulence. The system and method thereby establish, upon the entry of a high velocity fluid stream into the centrifugal field, non-turbulent and uniform flow conditions conducive to effective separation. The system and method also direct the fluid in a way the maximizes the effective surface area of the centrifugation chamber for separation. Effective separation can thereby be achieved at high inlet flow rates.
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公开(公告)号：CA1334190C
公开(公告)日：1995-01-31
申请号：CA613610
申请日：1989-09-27
Applicant: BAXTER INT
Inventor： DENNEHEY T MICHAEL , PERNIC STANLEY J , WEST JOSEPH C JR
Abstract: A centrifugal processing system for cultured cellular suspensions comprises a reservoir for pooling a desired volume of the cellular suspension from a plurality of individual containers in which the cellular suspension have been cultured. A centrifugation chamber is provided operative in response to centrifugal force for separating the cellular suspension into a cellular component and a supernatant. Fluid is conveyed from the reservoir into the centrifugation chamber at a high flow rate exceeding 1 liter per minute. The cellular component and supernatant are collected from the centrifugation chamber.
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公开(公告)号：CA2063262A1
公开(公告)日：1991-12-01
申请号：CA2063262
申请日：1991-04-01
Applicant: BAXTER INT
Inventor： DENNEHEY T MICHAEL , WEST JOSEPH C JR
Abstract: A device and method are provided for separating mononuclear cells from red blood cell depleted plasma in a centrifuge blood cell separator. The device includes an inlet for receiving plasma, an area for receiving mononuclear cells, and an outlet for receiving mononuclear cell depleted plasma. The distance and flow path between the inlet and outlet being so constructed and arranged as to cause mononuclear cells to sediment out into the area for receiving the mononuclear cells and causing at least 66% of the platelets contained in the plasma to flow to and through the outlet.
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