公开(公告)号：WO0062820A3

公开(公告)日：2001-03-08

申请号：PCT/US0009751

申请日：2000-04-12

Applicant: BAXTER INT

Inventor： BILSTAD ARNOLD C ,  BUCHANAN BRADLEY H ,  MARTTILA ALAN W ,  WOODWORTH ARCHIE

IPC: A61L2/24 ,  A61L2/00 ,  A61L2/08 ,  A61L2/10 ,  A61L2/14 ,  A61L2/20 ,  A61M39/18 ,  B29C65/00 ,  B29C65/02 ,  B29C65/04 ,  B29C65/10 ,  B29C65/48 ,  B67C7/00 ,  B65B55/02

CPC classification number: A61L2/00 ,  A61L2/08 ,  A61L2/087 ,  A61L2/14 ,  A61L2/208 ,  A61L2202/23 ,  A61L2202/24 ,  A61M39/18 ,  B29C65/02 ,  B29C65/04 ,  B29C65/103 ,  B29C65/4895 ,  B29C66/0018 ,  B29C66/1142 ,  B29C66/5221 ,  B29C66/5229 ,  B29C66/52293 ,  B29C66/52298 ,  B29C66/73921 ,  B29C66/81431 ,  B29C66/83221 ,  B29C66/857 ,  B29L2023/007 ,  B67C7/0073

Abstract: The connection, assembly, or fill of two or more pre-sterilized components having at least one terminal end each for attachment to another component, and an apparatus for performing such a connection, while maintaining the sterility of the components is disclosed. The resulting connection is made permanent by bonding the contacting components together using either a solvent bonding technique, a radio frequency sealer, a heat sealer, or any other suitable process. The connection is preferably made within an active sterile field. Using a low-voltage electron beam instrument, such as the MIN-EB , a suitable sterile field sphere can be created. The terminal ends of the multiple components remain withing the sterile field sphere until the possibility of contamination within the sealed components is significantly reduced to industry acceptable standards.

Abstract translation: 公开了两个或更多个预灭菌组件的连接，组装或填充，其具有至少一个终端，用于附接到另一组件，以及用于执行这种连接的设备，同时保持组件的无菌性。 通过使用溶剂粘合技术，无线电频率封隔器，热封机或任何其它合适的工艺将接触部件粘合在一起，使得到的连接永久化。 连接优选在活性无菌区域内进行。 使用诸如MIN-EB TM的低电压电子束仪器可以产生合适的无菌场球。 多个部件的末端保留无菌场球，直到密封部件内污染的可能性显着降低到工业上可接受的标准。

公开(公告)号：WO2009042261A1

公开(公告)日：2009-04-02

申请号：PCT/US2008066101

申请日：2008-06-06

Applicant: BAXTER INT ,  BAXTER HEALTHCARE SA ,  MARTTILA ALAN W ,  CHAN WILLIAM W ,  BHAGTANI REEMA ASHOK

Inventor： MARTTILA ALAN W ,  CHAN WILLIAM W ,  BHAGTANI REEMA ASHOK

IPC: A61M1/36 ,  A61M5/168

CPC classification number: A61M5/5086 ,  A61B5/02042 ,  A61M1/3653 ,  A61M1/3656 ,  A61M1/3659 ,  A61M5/158 ,  A61M5/16836 ,  A61M2005/1588 ,  A61M2205/13 ,  A61M2205/3592

Abstract: A monitor for an extracorporeal therapy access site is disclosed. The monitor includes a bandage atop or adjacent the access site and a sensor for monitoring the bandage. The bandage includes a layer of polymer that expands when wetted with blood. The expansion causes a break in continuity of the sensor, or in an alternate embodiment, causes a sensor to cease detecting a target. When the break occurs, the control circuit monitoring the bandage sends a signal that a break has occurred, and a remote monitor then takes appropriate action, such as ceasing therapy, sending an alert, or sounding an alarm. In another embodiment, connecting wires in a continuity circuit are held apart by a polymer that dissolves when contacted by blood. If a leak occurs and a small portion of the polymer dissolves, the wires make contact, thus detecting a blood leak.

Abstract translation: 公开了一种用于体外治疗进入点的监视器。 监护仪包括进入部位顶部或附近的绷带和监测绷带的传感器。 绷带包括一层聚合物，当被血液弄湿时会膨胀。 扩展导致传感器的连续性中断，或者在替代实施例中，导致传感器停止检测目标。 当发生中断时，监控绷带的控制电路发出发生中断的信号，然后远程监护仪采取适当的措施，例如停止治疗，发送警报或发出警报。 在另一个实施方案中，连续电路中的连接线由被血液接触时溶解的聚合物保持分开。 如果发生泄漏并且聚合物的一小部分溶解，则导线接触，从而检测到血液泄漏。

公开(公告)号：WO02101269A3

公开(公告)日：2003-03-20

申请号：PCT/US0218633

申请日：2002-06-12

Applicant: BAXTER INT

Inventor： WILLIAMSON MARK E ,  ARIAGNO SCOTT R ,  MARTTILA ALAN W ,  BILSTAD ARNOLD C ,  DIPERNA PAUL M ,  PRISCO MICHAEL R ,  PENNINGTON DAVID W ,  YARDIMCI ATIF M ,  SMITH SIDNEY T ,  PERRY MARK C ,  BELLOTTI MARC

IPC: F16K7/12 ,  A47G21/18 ,  A61J1/05 ,  A61J1/10 ,  A61J15/00 ,  A61M11/06 ,  A61M15/00 ,  A61M39/00 ,  A61M39/22 ,  F16K7/17 ,  F16K15/02 ,  F16K15/03 ,  F16K15/14 ,  A61M39/24 ,  B65D47/20

CPC classification number: A61J7/0053 ,  A47G21/185 ,  A61J1/10 ,  A61J1/1475 ,  A61J7/0046 ,  A61M39/227 ,  A61M39/24 ,  A61M2039/2406 ,  A61M2039/242 ,  A61M2039/244 ,  A61M2039/2486 ,  F16K15/14 ,  F16K15/147 ,  Y10S137/907 ,  Y10T137/7781 ,  Y10T137/7836 ,  Y10T137/7882 ,  Y10T137/789

Abstract: A vacuum demand valve (10) is capable of delivering a flowable material. The valve (10) has a housing (11) having a proximal end (14), a distal end (16), an intermediate segment (18) therebetween defining a passageway (24) wherein the flowable substance can flow from the proximal end (14) to the distal end (16). The housing (11) can be tubing. A valve member (20) is located along the intermediate segment (18). The valve member (20) has a closed condition wherein the flowable material from the proximal end (14) to the distal end (16) is stopped and an open condition wherein the flow of the flowable material from the proximal end (14) to the distal end (16) is unstopped. The valve member (20) is biased in the closed condition and is responsive to a partial vacuum provided by the user through the passageway (24) for placing the valve member (20) in the open condition.

Abstract translation: 真空需求阀（10）能够输送可流动的材料。 阀（10）具有壳体（11），其具有近端（14），远端（16），间隔开的中间段（18），限定通道（24），其中可流动物质可以从近端（ 14）到远端（16）。 外壳（11）可以是管道。 阀构件（20）沿着中间段（18）定位。 阀构件（20）具有闭合状态，其中从近端（14）到远端（16）的可流动材料停止，并且打开状态，其中可流动材料从近端（14）流到 远端（16）不受阻挡。 阀构件（20）在关闭状态下被偏压并且响应于用户通过通道（24）提供的用于将阀构件（20）置于打开状态的部分真空。

公开(公告)号：CA2649673A1

公开(公告)日：2000-10-26

申请号：CA2649673

申请日：2000-04-12

Applicant: BAXTER INT

Inventor： BILSTAD ARNOLD C ,  BUCHANAN BRADLEY H ,  MARTTILA ALAN W ,  WOODWORTH ARCHIE

IPC: A61L2/24 ,  B65B55/02 ,  A61L2/00 ,  A61L2/08 ,  A61L2/10 ,  A61L2/14 ,  A61L2/20 ,  A61M39/18 ,  B29C65/00 ,  B29C65/02 ,  B29C65/04 ,  B29C65/10 ,  B29C65/48 ,  B67C7/00

Abstract: The connection, assembly, or fill of two or more pre-sterilized components having at least one terminal end each for attachment to another component, and an apparatus for performing such a connection, while maintaining the sterility of the components is disclosed. The resulting connection is made permanent by bonding the contacting components together using either a solvent bonding technique, a radio frequency sealer, a heat sealer, or any other suitable process. The connection is preferably made within an active sterile field. Using a low-voltage electron beam instrument, such as the MIN-EB(TM), a suitable sterile field sphere can be created. The terminal ends of the multiple components remain within the sterile field sphere until the possibility of contamination within the sealed components is significantly reduced to industry acceptable standards.

公开(公告)号：BR0210919A

公开(公告)日：2006-10-24

申请号：BR0210919

申请日：2002-06-12

Applicant: BAXTER INT

Inventor： WILLIAMSON MARK E ,  ARIAGNO SCOTT R ,  MARTTILA ALAN W ,  BILSTAD ARNOLD C ,  DIPERNA PAUL M ,  PRISCO MICHAEL R ,  PENNINGTON DAVID W ,  YARDIMCI ATIF M ,  SMITH SIDNEY T ,  PERRY MARK C ,  BELLOTTI MARC

IPC: F16K7/12 ,  A47G21/18 ,  A61J1/05 ,  A61J1/10 ,  A61J15/00 ,  A61M11/06 ,  A61M15/00 ,  A61M39/00 ,  A61M39/22 ,  F16K7/17 ,  F16K15/02 ,  F16K15/03 ,  F16K15/14 ,  B65D47/20 ,  A61M39/24

Abstract: A vacuum demand valve for delivering a flowable material is disclosed. The valve has a housing having a proximal end, a distal end, an intermediate segment therebetween defining a passageway wherein the flowable substance can flow from the proximal end to the distal end. The housing can be a tubing. A valve member is located along the intermediate segment. The valve member has a closed condition wherein the flow of the flowable material from the proximal end to the distal end is stopped and an open condition wherein the flow of the flowable material from the proximal end to the distal end is unstopped. The valve member is biased in the closed condition and is responsive to a partial vacuum provided by the user through the passageway for placing the valve member in the open condition.

公开(公告)号：CA2649673C

公开(公告)日：2010-06-15

申请号：CA2649673

申请日：2000-04-12

Applicant: BAXTER INT

Inventor： BILSTAD ARNOLD C ,  BUCHANAN BRADLEY H ,  MARTTILA ALAN W ,  WOODWORTH ARCHIE

IPC: A61L2/24 ,  B65B55/02 ,  A61L2/00 ,  A61L2/08 ,  A61L2/10 ,  A61L2/14 ,  A61L2/20 ,  A61M39/18 ,  B29C65/00 ,  B29C65/02 ,  B29C65/04 ,  B29C65/10 ,  B29C65/48 ,  B67C7/00 ,  B67D99/00

Abstract: A method for sterile filling a pre-sterilized container having a filling port with a bulk sterile fluid comprises the steps of, establishing an active sterile field, introducing the filling port of the pre-sterilized container into the active sterile field, transferring an aliquot of the bulk sterile fluid from a supply container to the pre-sterilized container through the filling port while in the active sterile field and removing the filling port of the pre-sterilized container from the active sterile field.

公开(公告)号：CA2365557C

公开(公告)日：2010-03-30

申请号：CA2365557

申请日：2000-04-12

Applicant: BAXTER INT

Inventor： BILSTAD ARNOLD C ,  BUCHANAN BRADLEY H ,  MARTTILA ALAN W ,  WOODWORTH ARCHIE

IPC: A61L2/24 ,  A61M39/18 ,  A61L2/00 ,  A61L2/08 ,  A61L2/10 ,  A61L2/14 ,  A61L2/20 ,  B29C65/00 ,  B29C65/02 ,  B29C65/04 ,  B29C65/10 ,  B29C65/48 ,  B65B55/02 ,  B67C7/00

Abstract: The connection, assembly, or fill of two or more pre-sterilized components having at least one terminal end each for attachment to another component, and an apparatus for performing such a connection, while maintaining the sterility of the components is disclosed. The resulting connection is made permanent by bonding the contacting components together using either a solvent bonding technique, a radio frequency sealer, a heat sealer, or any other suitable process. The connection is preferably made within an active sterile field. Using a low-voltage electron beam instrument, such as the MIN-EB.TM., a suitable sterile field sphere can be created. The terminal ends of the multiple components remain withing the sterile field sphere until the possibility of contamination within the sealed components is significantly reduced to industry acceptable standards.

公开(公告)号：AU760376B2

公开(公告)日：2003-05-15

申请号：AU4455600

申请日：2000-04-12

Applicant: BAXTER INT

Inventor： BILSTAD ARNOLD C ,  BUCHANAN BRADLEY H ,  MARTTILA ALAN W ,  WOODWORTH ARCHIE

IPC: A61L2/24 ,  A61L2/00 ,  A61L2/08 ,  A61L2/10 ,  A61L2/14 ,  A61L2/20 ,  A61M39/18 ,  B29C65/00 ,  B29C65/02 ,  B29C65/04 ,  B29C65/10 ,  B29C65/48 ,  B67C7/00

Abstract: The connection, assembly, or fill of two or more pre-sterilized components having at least one terminal end each for attachment to another component, and an apparatus for performing such a connection, while maintaining the sterility of the components is disclosed. The resulting connection is made permanent by bonding the contacting components together using either a solvent bonding technique, a radio frequency sealer, a heat sealer, or any other suitable process. The connection is preferably made within an active sterile field. Using a low-voltage electron beam instrument, such as the MIN-EB(TM), a suitable sterile field sphere can be created. The terminal ends of the multiple components remain within the sterile field sphere until the possibility of contamination within the sealed components is significantly reduced to industry acceptable standards.

公开(公告)号：DE60043813D1

公开(公告)日：2010-03-25

申请号：DE60043813

申请日：2000-04-12

Applicant: BAXTER INT

Inventor： BILSTAD ARNOLD C ,  BUCHANAN BRADLEY H ,  MARTTILA ALAN W ,  WOODWORTH ARCHIE

IPC: A61L2/00 ,  A61L2/24 ,  A61L2/08 ,  A61L2/10 ,  A61L2/14 ,  A61L2/20 ,  A61M39/18 ,  B29C65/00 ,  B29C65/02 ,  B29C65/04 ,  B29C65/10 ,  B29C65/48 ,  B67C7/00

Abstract: The connection, assembly, or fill of two or more pre-sterilized components having at least one terminal end each for attachment to another component, and an apparatus for performing such a connection, while maintaining the sterility of the components is disclosed. The resulting connection is made permanent by bonding the contacting components together using either a solvent bonding technique, a radio frequency sealer, a heat sealer, or any other suitable process. The connection is preferably made within an active sterile field. Using a low-voltage electron beam instrument, such as the MIN-EB(TM), a suitable sterile field sphere can be created. The terminal ends of the multiple components remain within the sterile field sphere until the possibility of contamination within the sealed components is significantly reduced to industry acceptable standards.

公开(公告)号：AT457184T

公开(公告)日：2010-02-15

申请号：AT00925941

申请日：2000-04-12

Applicant: BAXTER INT

Inventor： BILSTAD ARNOLD C ,  BUCHANAN BRADLEY H ,  MARTTILA ALAN W ,  WOODWORTH ARCHIE

IPC: A61L2/24 ,  A61M39/18 ,  A61L2/00 ,  A61L2/08 ,  A61L2/10 ,  A61L2/14 ,  A61L2/20 ,  B29C65/00 ,  B29C65/02 ,  B29C65/04 ,  B29C65/10 ,  B29C65/48 ,  B67C7/00

Abstract: The connection, assembly, or fill of two or more pre-sterilized components having at least one terminal end each for attachment to another component, and an apparatus for performing such a connection, while maintaining the sterility of the components is disclosed. The resulting connection is made permanent by bonding the contacting components together using either a solvent bonding technique, a radio frequency sealer, a heat sealer, or any other suitable process. The connection is preferably made within an active sterile field. Using a low-voltage electron beam instrument, such as the MIN-EB(TM), a suitable sterile field sphere can be created. The terminal ends of the multiple components remain within the sterile field sphere until the possibility of contamination within the sealed components is significantly reduced to industry acceptable standards.