公开(公告)号：DE69503435D1

公开(公告)日：1998-08-20

申请号：DE69503435

申请日：1995-02-03

Applicant: BAXTER INT

Inventor： SOLTYS PAUL ,  OFSTHUN NORMA

IPC: C12M1/12 ,  A61M1/18 ,  A61M1/34 ,  B01D61/14 ,  B01D61/24 ,  B01D61/30 ,  B01D63/02 ,  B01D65/08 ,  B01D69/02 ,  B01D69/08 ,  B01D69/12 ,  C12M3/06

Abstract: Dual-skinned membranes are provided useful as one-way or rectifying membranes which reduce back filtration of solute molecules in dialysis and which improve nutrient supply and product recovery in membrane bioreactors. The membranes are dual-skinned polymeric materials preferably in the form of hollow fibers. The membranes have skins of polymer on the opposite sides with differing permeability to solutes and sieving coefficient characteristics. The skin on each side have pores that are invisible at 10,000 times magnification. A microporous structure between the skins contains pores capable of retaining solutes in a molecular weight range of about 5000 to 200,000 in an increased concentration between the interior and the exterior skins. Improved dialysis devices are formed by using bundles of the hollow fiber membranes as a dialysis member having rectifying properties.

公开(公告)号：AT168281T

公开(公告)日：1998-08-15

申请号：AT95909461

申请日：1995-02-03

Applicant: BAXTER INT

Inventor： SOLTYS PAUL ,  OFSTHUN NORMA

IPC: C12M1/12 ,  A61M1/18 ,  A61M1/34 ,  B01D61/14 ,  B01D61/24 ,  B01D61/30 ,  B01D63/02 ,  B01D65/08 ,  B01D69/02 ,  B01D69/08 ,  B01D69/12 ,  C12M3/06

Abstract: Dual-skinned membranes are provided useful as one-way or rectifying membranes which reduce back filtration of solute molecules in dialysis and which improve nutrient supply and product recovery in membrane bioreactors. The membranes are dual-skinned polymeric materials preferably in the form of hollow fibers. The membranes have skins of polymer on the opposite sides with differing permeability to solutes and sieving coefficient characteristics. The skin on each side have pores that are invisible at 10,000 times magnification. A microporous structure between the skins contains pores capable of retaining solutes in a molecular weight range of about 5000 to 200,000 in an increased concentration between the interior and the exterior skins. Improved dialysis devices are formed by using bundles of the hollow fiber membranes as a dialysis member having rectifying properties.

公开(公告)号：DE69419095T2

公开(公告)日：2000-02-03

申请号：DE69419095

申请日：1994-02-28

Applicant: BAXTER INT

Inventor： OFSTHUN NORMA ,  HENDERSON LEE ,  BROWN RICHARD ,  PAULEY ROBIN

IPC: A61M1/18 ,  B01D61/14 ,  B01D61/24 ,  B01D69/02 ,  B01D69/08 ,  C12M1/12 ,  C12M3/06

Abstract: The invention provides dual-skinned membrane useful as one way or rectifying membranes which reduce back filtration of solute molecules in dialysis and which improve nutrient supply and product recovery in membrane bioreactors. The membranes are dual-skinned polymeric materials preferably in the form of hollow fibers. The membranes have skins of polymer on the opposite sides with differing permeability to solutes and sieving coefficient characteristics. The skin on each side have pores that are invisible at 10,000 times magnification, the microporous structure between said skins contains pores capable of retaining solutes in a molecular weight range of about 5000 to 200,000 in an increased concentration between the interior and the exterior skins. Improved dialysis devices are formed by using bundles of the hollow fiber membranes as a dialysis means having rectifying properties.

公开(公告)号：DE69419095D1

公开(公告)日：1999-07-22

申请号：DE69419095

申请日：1994-02-28

Applicant: BAXTER INT

Inventor： OFSTHUN NORMA ,  HENDERSON LEE ,  BROWN RICHARD ,  PAULEY ROBIN

IPC: A61M1/18 ,  B01D61/14 ,  B01D61/24 ,  B01D69/02 ,  B01D69/08 ,  C12M1/12 ,  C12M3/06

Abstract: The invention provides dual-skinned membrane useful as one way or rectifying membranes which reduce back filtration of solute molecules in dialysis and which improve nutrient supply and product recovery in membrane bioreactors. The membranes are dual-skinned polymeric materials preferably in the form of hollow fibers. The membranes have skins of polymer on the opposite sides with differing permeability to solutes and sieving coefficient characteristics. The skin on each side have pores that are invisible at 10,000 times magnification, the microporous structure between said skins contains pores capable of retaining solutes in a molecular weight range of about 5000 to 200,000 in an increased concentration between the interior and the exterior skins. Improved dialysis devices are formed by using bundles of the hollow fiber membranes as a dialysis means having rectifying properties.

公开(公告)号：ES2121349T3

公开(公告)日：1998-11-16

申请号：ES95909461

申请日：1995-02-03

Applicant: BAXTER INT

Inventor： SOLTYS PAUL ,  OFSTHUN NORMA

IPC: C12M1/12 ,  A61M1/18 ,  A61M1/34 ,  B01D61/14 ,  B01D61/24 ,  B01D61/30 ,  B01D63/02 ,  B01D65/08 ,  B01D69/02 ,  B01D69/08 ,  B01D69/12 ,  C12M3/06

Abstract: Dual-skinned membranes are provided useful as one-way or rectifying membranes which reduce back filtration of solute molecules in dialysis and which improve nutrient supply and product recovery in membrane bioreactors. The membranes are dual-skinned polymeric materials preferably in the form of hollow fibers. The membranes have skins of polymer on the opposite sides with differing permeability to solutes and sieving coefficient characteristics. The skin on each side have pores that are invisible at 10,000 times magnification. A microporous structure between the skins contains pores capable of retaining solutes in a molecular weight range of about 5000 to 200,000 in an increased concentration between the interior and the exterior skins. Improved dialysis devices are formed by using bundles of the hollow fiber membranes as a dialysis member having rectifying properties.

公开(公告)号：DE69503435T2

公开(公告)日：1999-04-22

申请号：DE69503435

申请日：1995-02-03

Applicant: BAXTER INT

Inventor： SOLTYS PAUL ,  OFSTHUN NORMA

IPC: C12M1/12 ,  A61M1/18 ,  A61M1/34 ,  B01D61/14 ,  B01D61/24 ,  B01D61/30 ,  B01D63/02 ,  B01D65/08 ,  B01D69/02 ,  B01D69/08 ,  B01D69/12 ,  C12M3/06

Abstract: Dual-skinned membranes are provided useful as one-way or rectifying membranes which reduce back filtration of solute molecules in dialysis and which improve nutrient supply and product recovery in membrane bioreactors. The membranes are dual-skinned polymeric materials preferably in the form of hollow fibers. The membranes have skins of polymer on the opposite sides with differing permeability to solutes and sieving coefficient characteristics. The skin on each side have pores that are invisible at 10,000 times magnification. A microporous structure between the skins contains pores capable of retaining solutes in a molecular weight range of about 5000 to 200,000 in an increased concentration between the interior and the exterior skins. Improved dialysis devices are formed by using bundles of the hollow fiber membranes as a dialysis member having rectifying properties.

公开(公告)号：CA2158141A1

公开(公告)日：1995-08-17

申请号：CA2158141

申请日：1995-02-03

Applicant: BAXTER INT

Inventor： SOLTYS PAUL ,  OFSTHUN NORMA

IPC: C12M1/12 ,  A61M1/18 ,  A61M1/34 ,  B01D61/14 ,  B01D61/24 ,  B01D61/30 ,  B01D63/02 ,  B01D65/08 ,  B01D69/02 ,  B01D69/08 ,  B01D69/12 ,  C12M3/06 ,  C12P1/00

Abstract: A method for providing dual-skinned membranes (88) useful as one-way or rectifying membranes which reduce back filtration of solute molecules in dialysis and which improve nutrient supply and product recovery in membrane bioreactors. The membranes are dual-skinned polymeric materials preferably in the form of hollow fibers. The membranes have skins (12, 14) of polymer on the opposite sides with differing permeability to solutes and sieving coefficient characteristics. The skin on each side has pores that are invisible at 10,000 times magnification. A microporous structure (16) between the skins contains pores capable of retaining solutes in a molecular weight range of about 5000 to 200,000 in an increased concentration between the interior (14) and the exterior (12) skins. Dialysis devices are formed by using bundles of the hollow fiber membranes as a dialysis member having rectifying properties. By repeatedly cycling solution back and forth across the membrane (88), the solute can be separated and concentrated on one side of the membrane (88).