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    SYSTEMS AND METHODS FOR PERFORMING PERITONEAL DIALYSIS
    1.
    发明申请
    SYSTEMS AND METHODS FOR PERFORMING PERITONEAL DIALYSIS 审中-公开
    用于执行腹膜透析的系统和方法

    公开(公告)号：WO2004009158A2

    公开(公告)日：2004-01-29

    申请号：PCT/US0322267

    申请日：2003-07-16

    Applicant: BAXTER INT ,  BAXTER HEALTHCARE SA

    Inventor： CHILDERS ROBERT W ,  BROWN DAVID S ,  WARIAR RAMESH ,  KAROOR SUJATHA ,  DIN SHAHID ,  MARTIS LEO ,  BUCHMANN CODY ,  SOLTYS PAUL

    IPC: A61M1/14 ,  A61M1/16 ,  A61M1/28

    CPC classification number: A61M1/1696 ,  A61M1/1656 ,  A61M1/1658 ,  A61M1/166 ,  A61M1/28 ,  A61M1/284 ,  A61M1/285 ,  A61M1/287 ,  A61M1/288 ,  A61M2202/0413 ,  A61M2205/12 ,  A61M2205/3306 ,  A61M2205/3327

    Abstract: In a peritoneal dialysis embodiment of the present invention, spent dialysate from the patient's peritoneal cavity passes, along a patient loop, through a dialyzer having a membrane that separates waste components from the spent dialysate, wherein the patient loop returns fresh dialysate to the patient's peritoneal cavity. The waste components are carried away in a second regeneration loop to a regeneration unit or sorbent cartridge, which absorbs the waste components. The regeneration unit removes undesirable components in the dialysate that were removed from the patient loop by the dialyzer, for example, excess water (ultrafiltrate or UF), toxins and metabolic wastes. Desirable components can be added to the dialysate by the system, such as glucose and electrolytes. The additives assist in maintaining the proper osmotic gradients in the patient to perform dialysis and provide the necessary compounds to the patient.

    Abstract translation: 在本发明的腹膜透析实施方案中，来自患者腹膜腔的用过的透析液沿着患者环路通过具有膜的透析器，该膜将废组分与用过的透析液分开，其中患者环路将新鲜透析液返回至患者的腹膜 腔。 废物组分在第二再生回路中被带走到吸收废物组分的再生单元或吸附剂盒。 再生单元除去透析器中由透析器移除的透析液中不需要的成分，例如过量的水（超滤液或UF），毒素和代谢废物。 理想的组分可以通过该系统添加到透析液中，例如葡萄糖和电解质。 添加剂有助于维持患者适当的渗透梯度以进行透析并向患者提供必需的化合物。

    Systems and methods for performing peritoneal dialysis
    2.
    发明专利
    Systems and methods for performing peritoneal dialysis 未知

    公开(公告)号：AU2003249296A8

    公开(公告)日：2004-02-09

    申请号：AU2003249296

    申请日：2003-07-16

    Applicant: BAXTER HEALTHCARE SA ,  BAXTER INT

    Inventor： CHILDERS ROBERT W ,  BROWN DAVID S ,  WARIAR RAMESH ,  KAROOR SUJATHA ,  DIN SHAHID ,  MARTIS LEO ,  BUCHMANN CODY ,  SOLTYS PAUL

    IPC: A61M1/14 ,  A61M1/16 ,  A61M1/28

    Abstract: A system for dialysis is disclosed. An example peritoneal dialysis system includes a peritoneal dialysis machine including a pumping mechanism, and a sensor configured to measure a property of peritoneal dialysis fluid. The peritoneal dialysis system also includes a disposable cassette operable with the peritoneal dialysis machine. The disposable cassette includes a fluid source inlet for accepting fluid from a fluid source and a fluid flow path in fluid communication with the fluid source inlet. The fluid flow path includes a pump chamber operable with the pumping mechanism to pump fluid through the fluid flow path. The disposable cassette also includes a concentrate inlet for fluidly communicating concentrate to the fluid flow path, and a sensor chamber located along the fluid flow path and operable with the sensor. The sensor is configured to provide feedback to the peritoneal dialysis machine for mixing the concentrate for forming peritoneal dialysis fluid.

    3.
    发明专利
    未知

    公开(公告)号：DE69503435T2

    公开(公告)日：1999-04-22

    申请号：DE69503435

    申请日：1995-02-03

    Applicant: BAXTER INT

    Inventor： SOLTYS PAUL ,  OFSTHUN NORMA

    IPC: C12M1/12 ,  A61M1/18 ,  A61M1/34 ,  B01D61/14 ,  B01D61/24 ,  B01D61/30 ,  B01D63/02 ,  B01D65/08 ,  B01D69/02 ,  B01D69/08 ,  B01D69/12 ,  C12M3/06

    Abstract: Dual-skinned membranes are provided useful as one-way or rectifying membranes which reduce back filtration of solute molecules in dialysis and which improve nutrient supply and product recovery in membrane bioreactors. The membranes are dual-skinned polymeric materials preferably in the form of hollow fibers. The membranes have skins of polymer on the opposite sides with differing permeability to solutes and sieving coefficient characteristics. The skin on each side have pores that are invisible at 10,000 times magnification. A microporous structure between the skins contains pores capable of retaining solutes in a molecular weight range of about 5000 to 200,000 in an increased concentration between the interior and the exterior skins. Improved dialysis devices are formed by using bundles of the hollow fiber membranes as a dialysis member having rectifying properties.

    A METHOD FOR CONCENTRATING A SOLUTE WITH AN OSCILLATING FILTRATION DEVICE
    4.
    发明专利
    A METHOD FOR CONCENTRATING A SOLUTE WITH AN OSCILLATING FILTRATION DEVICE 未知

    公开(公告)号：CA2158141A1

    公开(公告)日：1995-08-17

    申请号：CA2158141

    申请日：1995-02-03

    Applicant: BAXTER INT

    Inventor： SOLTYS PAUL ,  OFSTHUN NORMA

    IPC: C12M1/12 ,  A61M1/18 ,  A61M1/34 ,  B01D61/14 ,  B01D61/24 ,  B01D61/30 ,  B01D63/02 ,  B01D65/08 ,  B01D69/02 ,  B01D69/08 ,  B01D69/12 ,  C12M3/06 ,  C12P1/00

    Abstract: A method for providing dual-skinned membranes (88) useful as one-way or rectifying membranes which reduce back filtration of solute molecules in dialysis and which improve nutrient supply and product recovery in membrane bioreactors. The membranes are dual-skinned polymeric materials preferably in the form of hollow fibers. The membranes have skins (12, 14) of polymer on the opposite sides with differing permeability to solutes and sieving coefficient characteristics. The skin on each side has pores that are invisible at 10,000 times magnification. A microporous structure (16) between the skins contains pores capable of retaining solutes in a molecular weight range of about 5000 to 200,000 in an increased concentration between the interior (14) and the exterior (12) skins. Dialysis devices are formed by using bundles of the hollow fiber membranes as a dialysis member having rectifying properties. By repeatedly cycling solution back and forth across the membrane (88), the solute can be separated and concentrated on one side of the membrane (88).

    7.
    发明专利
    未知

    公开(公告)号：ES2121349T3

    公开(公告)日：1998-11-16

    申请号：ES95909461

    申请日：1995-02-03

    Applicant: BAXTER INT

    Inventor： SOLTYS PAUL ,  OFSTHUN NORMA

    IPC: C12M1/12 ,  A61M1/18 ,  A61M1/34 ,  B01D61/14 ,  B01D61/24 ,  B01D61/30 ,  B01D63/02 ,  B01D65/08 ,  B01D69/02 ,  B01D69/08 ,  B01D69/12 ,  C12M3/06

    Abstract: Dual-skinned membranes are provided useful as one-way or rectifying membranes which reduce back filtration of solute molecules in dialysis and which improve nutrient supply and product recovery in membrane bioreactors. The membranes are dual-skinned polymeric materials preferably in the form of hollow fibers. The membranes have skins of polymer on the opposite sides with differing permeability to solutes and sieving coefficient characteristics. The skin on each side have pores that are invisible at 10,000 times magnification. A microporous structure between the skins contains pores capable of retaining solutes in a molecular weight range of about 5000 to 200,000 in an increased concentration between the interior and the exterior skins. Improved dialysis devices are formed by using bundles of the hollow fiber membranes as a dialysis member having rectifying properties.

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