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1.发明申请METHOD AND APPARATUS FOR THE DETECTION OF THE PRESENCE OF A BACTERIA IN THE GASTROINTESTINAL TRACT OF A SUBJECT 审中-公开用于检测细菌在原发性胃肠道疾病中的存在的方法和装置
公开(公告)号：WO2004006766A3
公开(公告)日：2004-05-06
申请号：PCT/US0322002
申请日：2003-07-11
Applicant: BAXTER INT , BAXTER HEALTHCARE SA , PAN LI
Inventor： PAN LI
IPC: A61B5/083 , A61B5/097 , G01N33/497
Abstract: The present invention generally relates to a method and an apparatus to detect the presence of a bacteria in a subject. More particularly, the method is directed toward the detection of a bacteria which is associated with catalyzing urea to carbon dioxide and ammonia when present in the gastrointestinal tract of a subject. The method comprises administering urea to a subject, obtaining a fluid sample from the subject after the administration of the urea and then determining the presence or amount of ammonia gas in the fluid sample. The apparatus facilitates ease of implementing the method and facilitates accuracy and speed of obtaining the test result.
Abstract translation: 本发明一般涉及检测受试者中细菌存在的方法和装置。 更具体地，该方法涉及当存在于受试者的胃肠道中时与尿素催化成二氧化碳和氨相关联的细菌的检测。 该方法包括向受试者施用尿素，在施用尿素后从受试者获得流体样品，然后确定流体样品中氨气的存在或数量。 该装置便于实现该方法，并且有助于获得测试结果的准确性和速度。
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公开(公告)号：WO03097121A2
公开(公告)日：2003-11-27
申请号：PCT/US0312816
申请日：2003-04-23
Applicant: BAXTER INT
Inventor： PAN LI , WARIAR RAMESH , MARTIS LEO , HOLMES CLIFF , CHILDERS ROBERT , DIN SHAHID
CPC classification number: B01D61/32 , A61M1/1609 , A61M1/28
Abstract: A biosensor capable of monitoring a number of different constituents of a dialysate solution used during dialysis therapy is provided. The biosensor of the present invention includes an integrated array of reactive elements and sensing elements that can be hydraulically coupled to the dialysate solution. In this regard, the biosensor can be utilized to provide on-line monitoring of total solutes removed from a patient during dialysis therapy, infection levels, and/or other desirable parameters such that an overall assessment of dialysis therapy can be readily evaluated.
Abstract translation: 提供能够监测在透析治疗期间使用的透析液的多种不同成分的生物传感器。 本发明的生物传感器包括能够液压耦合到透析液的反应元件和感测元件的集成阵列。 在这方面，生物传感器可用于提供在透析治疗，感染水平和/或其它期望参数期间从患者移除的总溶质的在线监测，使得可以容易地评估透析治疗的总体评估。
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公开(公告)号：AU2003249234A8
公开(公告)日：2004-02-02
申请号：AU2003249234
申请日：2003-07-11
Applicant: BAXTER HEALTHCARE SA , BAXTER INT
Inventor： PAN LI
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公开(公告)号：MX2008015079A
公开(公告)日：2009-02-10
申请号：MX2008015079
申请日：2007-05-24
Applicant: BAXTER INT
Inventor： CHILDERS ROBERT , KEELING SCOTT , PAN LI
Abstract: Una máquina de diálisis peritoneal incluye: (i) una bolsa de suministro (24a); (ii) un aparato (24)configurado para soportar la bolsa de suministro, la bolsa de suministro está ubicada por arriba de la cavidad peritoneal de un paciente; (iii) una fuente de vacío (70); (iv) una línea de paciente (56) configurada para ser conectada al paciente; (v) una línea de drenaje (58) configurada para ser conectada a un drenaje (60); y (vi) un implementador lógico (40) configurado para habilitar (a) dializado fresco para ser alimentado por gravedad desde la bolsa de suministro a través de la línea de paciente hacia la cavidad peritoneal durante un ciclo de llenado y (b) la fuente de vacío para hace que el dializado gastado sea extraído desde la cavidad peritoneal a través de la línea de drenaje hacia el drenaje durante un ciclo de drenaje.
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公开(公告)号：AU2003249234A1
公开(公告)日：2004-02-02
申请号：AU2003249234
申请日：2003-07-11
Applicant: BAXTER INT
Inventor： PAN LI
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Patent Agency Ranking">
公开(公告)号：AU2003225160A8
公开(公告)日：2003-12-02
申请号：AU2003225160
申请日：2003-04-23
Applicant: BAXTER INT
Inventor： PAN LI , MARTIS LEO , DIN SHAHID , CHILDERS ROBERT , WARIAR RAMESH , HOLMES CLIFF
Abstract: A biosensor capable of monitoring a number of different constituents of a dialysate solution used during dialysis therapy is provided. The biosensor of the present invention includes an integrated array of reactive elements and sensing elements that can be hydraulically coupled to the dialysate solution. In this regard, the biosensor can be utilized to provide on-line monitoring of total solutes removed from a patient during dialysis therapy, infection levels and/or other desirable parameters such that an overall assessment of dialysis therapy can be readily evaluated.
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公开(公告)号：AU2003237275A8
公开(公告)日：2003-12-31
申请号：AU2003237275
申请日：2003-05-28
Applicant: BAXTER HEALTHCARE SA , BAXTER INT
Inventor： PAN LI , WARIAR RAMESH
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公开(公告)号：AU2002366489A1
公开(公告)日：2003-06-30
申请号：AU2002366489
申请日：2002-09-20
Applicant: BAXTER INT
Inventor： PAN LI , WARIAR RAMESH , MAPLES VANCE
Abstract: A sensor which senses concentrations of a component of a fluid. In a dialysis system, the sensor can monitor the total ammonia and ammonium concentration in dialysate. The sensor has an optical indicator, such as an ammonia sensitive membrane, positioned in direct contact with the dialysate fluid when in use. The ammonia sensitive membrane has a variable optical indication, such as a variable color change, in relation to the concentration of ammonia in the dialysate. An optical reader reads the color change of the membrane to measure the total ammonia and ammonium concentration in the dialysate. The sensor can be used in the dialysis system to monitor the effectiveness of sorbants which remove ammonia/ammonium which is produced from an enzyme reaction with urea, the urea being removed from a patient during dialysis treatment.
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公开(公告)号：AU2003284063A8
公开(公告)日：2004-06-03
申请号：AU2003284063
申请日：2003-10-14
Applicant: BAXTER INT , BAXTER HEALTHCARE SA
Inventor： PAN LI , KELLAM BENJAMIN A , KEELING SCOTT
Abstract: A dialysis system and a method for automatically priming a dialyzer are provided. The priming of the dialyzer is accomplished in two steps; namely, the use of a blood pump to prime a dialyzer followed by the use of the blood pump and a dialysate pump to prime the dialyzer. The dialysis system filters a fluid through an extracorporeal circuit, a balanced flow loop and a dialysate loop which is connected to the dialyzer. The dialysis system and method may prevent air or air bubbles from entering the blood stream of a patient during dialysmis. Moreover, the dialysis system may be, for example, a hemodialysis or peritoneal dialysis system.
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公开(公告)号：AU2003284063A1
公开(公告)日：2004-06-03
申请号：AU2003284063
申请日：2003-10-14
Applicant: BAXTER INT
Inventor： PAN LI , KELLAM BENJAMIN A , KEELING SCOTT
Abstract: A dialysis system and a method for automatically priming a dialyzer are provided. The priming of the dialyzer is accomplished in two steps; namely, the use of a blood pump to prime a dialyzer followed by the use of the blood pump and a dialysate pump to prime the dialyzer. The dialysis system filters a fluid through an extracorporeal circuit, a balanced flow loop and a dialysate loop which is connected to the dialyzer. The dialysis system and method may prevent air or air bubbles from entering the blood stream of a patient during dialysmis. Moreover, the dialysis system may be, for example, a hemodialysis or peritoneal dialysis system.
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