公开(公告)号：AU2004234003A1

公开(公告)日：2004-11-11

申请号：AU2004234003

申请日：2004-04-29

Applicant: BAXTER INT

Inventor： RABINOW BARRETT E ,  REBBECK CHRISTINE L ,  KIPP JAMES E ,  SUN CHONG-SON ,  WONG JOSEPH CHUNG TAK ,  DOTY MARK J ,  PAPADOPOULOS PAVLOS ,  WHITE RANDY

IPC: A61K9/50 ,  A61K9/51 ,  A61K31/496 ,  A61K9/14

Abstract: The present invention relates to compositions of submicron- to micron-size particles of antimicrobial agents. More particularly the invention relates to a composition of an antimicrobial agent that renders the agent potent against organisms normally considered to be resistant to the agent. The composition comprises an aqueous suspension of submicron-tomicron-size particles containing the agent coated with at least one surfactant selected from the group consisting of: ionic surfactants, non-ionic surfactants, biologically derived surfactants, and amino acids and their derivatives. The particles have a volume-weighted mean particle size of less than 5 µm as measured by laser diffractonetry.

公开(公告)号：BRPI0409929A

公开(公告)日：2006-04-25

申请号：BRPI0409929

申请日：2004-04-29

Applicant: BAXTER INT

Inventor： RABINOW BARRETT E ,  WHITE RANDY ,  SUN CHONG-SON ,  WONG JOSEPH CHUNG TAK ,  KIPP JAMES E ,  DOTY MARK J ,  REBBECK CHRISTINE L ,  PAPADOPOULOS PAVLOS

IPC: A61K9/50 ,  A61K9/51 ,  A61K31/496 ,  A61K9/14

Abstract: The present invention relates to compositions of submicron- to micron-size particles of antimicrobial agents. More particularly the invention relates to a composition of an antimicrobial agent that renders the agent potent against organisms normally considered to be resistant to the agent. The composition comprises an aqueous suspension of submicron-tomicron-size particles containing the agent coated with at least one surfactant selected from the group consisting of: ionic surfactants, non-ionic surfactants, biologically derived surfactants, and amino acids and their derivatives. The particles have a volume-weighted mean particle size of less than 5 µm as measured by laser diffractonetry.

公开(公告)号：NO20055616L

公开(公告)日：2006-01-25

申请号：NO20055616

申请日：2005-11-28

Applicant: BAXTER INT

Inventor： KIPP JAMES E ,  WONG JOSEPH CHUNG TAK ,  DOTY MARK J ,  REBBECK CHRISTINE L ,  SUN CHONG-SON ,  PAPADOPOULOS PAVLOS ,  RABINOW BARRETT E ,  WHITE RANDY

IPC: A61K9/14 ,  A61K9/50 ,  A61K9/51 ,  A61K31/496

Abstract: The present invention relates to compositions of submicron- to micron-size particles of antimicrobial agents. More particularly the invention relates to a composition of an antimicrobial agent that renders the agent potent against organisms normally considered to be resistant to the agent. The composition comprises an aqueous suspension of submicron-tomicron-size particles containing the agent coated with at least one surfactant selected from the group consisting of: ionic surfactants, non-ionic surfactants, biologically derived surfactants, and amino acids and their derivatives. The particles have a volume-weighted mean particle size of less than 5 µm as measured by laser diffractonetry.

公开(公告)号：NO20055616A

公开(公告)日：2006-01-25

申请号：NO20055616

申请日：2005-11-28

Applicant: BAXTER INT

Inventor： KIPP JAMES E ,  WONG JOSEPH CHUNG TAK ,  DOTY MARK J ,  REBBECK CHRISTINE L ,  SUN CHONG-SON ,  PAPADOPOULOS PAVLOS ,  RABINOW BARRETT E ,  WHITE RANDY

IPC: A61K9/14 ,  A61K9/50 ,  A61K9/51 ,  A61K31/496

CPC classification number: A61K9/5123 ,  A61K9/5015 ,  A61K9/5138 ,  A61K9/5146 ,  A61K9/5192 ,  A61K31/496

公开(公告)号：NO20055616D0

公开(公告)日：2005-11-28

申请号：NO20055616

申请日：2005-11-28

Applicant: BAXTER INT

Inventor： KIPP JAMES E ,  WONG JOSEPH CHUNG TAK ,  DOTY MARK J ,  REBBECK CHRISTINE L ,  SUN CHONG-SON ,  PAPADOPOULOS PAVLOS ,  RABINOW BARRETT E ,  WHITE RANDY

IPC: A61K9/50 ,  A61K9/51 ,  A61K31/496 ,  A61K

Abstract: The present invention relates to compositions of submicron- to micron-size particles of antimicrobial agents. More particularly the invention relates to a composition of an antimicrobial agent that renders the agent potent against organisms normally considered to be resistant to the agent. The composition comprises an aqueous suspension of submicron-tomicron-size particles containing the agent coated with at least one surfactant selected from the group consisting of: ionic surfactants, non-ionic surfactants, biologically derived surfactants, and amino acids and their derivatives. The particles have a volume-weighted mean particle size of less than 5 µm as measured by laser diffractonetry.

公开(公告)号：CA2523151A1

公开(公告)日：2004-11-11

申请号：CA2523151

申请日：2004-04-29

Applicant: BAXTER INT

Inventor： RABINOW BARRETT E ,  WHITE RANDY ,  PAPADOPOULOS PAVLOS ,  REBBECK CHRISTINE L ,  SUN CHONG-SON ,  KIPP JAMES E ,  WONG JOSEPH CHUNG TAK ,  DOTY MARK J

IPC: A61K9/50 ,  A61K9/51 ,  A61K31/496 ,  A61K9/14

Abstract: The present invention relates to compositions of submicron- to micron-size particles of antimicrobial agents. More particularly the invention relates t o a composition of an antimicrobial agent that renders the agent potent agains t organisms normally considered to be resistant to the agent. The composition comprises an aqueous suspension of submicron-tomicron-size particles containing the agent coated with at least one surfactant selected from the group consisting of: ionic surfactants, non-ionic surfactants, biologically derived surfactants, and amino acids and their derivatives. The particles ha ve a volume-weighted mean particle size of less than 5 ~m as measured by laser diffractonetry.