公开(公告)号：WO2002031046A3

公开(公告)日：2002-04-18

申请号：PCT/US2001/030803

申请日：2001-09-28

Applicant: BAXTER INTERNATIONAL INC.

Inventor： YANG, Tahua ,  SHANG, Sherwin ,  WARREN, Joel ,  DING, Samuel ,  LING, Michael, T., K. ,  WOO, Lecon

IPC: C08L23/04

Abstract: The present invention provides a polymer blend for fabricating medical products. The blend has a first ethylene and α-olefin copolymer obtained using a single-site catalyst present in an amount by weight of from about 0 % to about 99 % by weight of the blend and having a melt flow index from about 0.1 g/10 min to about 5 g/10 min, a second ethylene and α-olefin copolymer obtained using a single-site catalyst and being present in an amount by weight of the blend from about 0 % to about 99 % and having a melt flow index from higher than about 5 g/10 min to about 20 g/10 min; and a third ethylene and α-olefin copolymer obtained using a single-site catalyst and being present in an amount by weight of the blend from about 0 % to about 99 % and having a melt flow index greater than about 20 g/10 min.

公开(公告)号：WO1994003544A1

公开(公告)日：1994-02-17

申请号：PCT/US1993006622

申请日：1993-07-14

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  DING, Samuel ,  QIN, Chuan ,  RABINOW, Barrett

IPC: C08L101/00

CPC classification number: A61J1/05 ,  A61J1/10 ,  A61L33/062 ,  C08L23/08 ,  C08L33/12 ,  C08L53/02 ,  C08L67/02 ,  C08L69/00 ,  C08L71/02 ,  C08L77/00 ,  C08L101/00 ,  G02B1/043 ,  Y10T428/1352 ,  Y10T428/1383 ,  Y10T428/1397 ,  Y10T428/249991 ,  Y10T428/249992 ,  Y10T428/249993 ,  C08L2666/04 ,  C08L2666/14 ,  C08L2666/02

Abstract: A protein-compatible polymer blend made from a water-soluble polymer and a matrix polymer. The glass transition temperature of either the water-soluble polymer or the matrix polymer is greater than the application temperature, i.e., the temperature at which the protein-compatible polymer blend is being used.

Abstract translation: 由水溶性聚合物和基质聚合物制成的与蛋白质相容的聚合物共混物。 水溶性聚合物或基质聚合物的玻璃化转变温度大于使用温度，即使用与蛋白质相容的聚合物共混物的温度。

公开(公告)号：WO2014066255A1

公开(公告)日：2014-05-01

申请号：PCT/US2013/065953

申请日：2013-10-21

Applicant: BAXTER INTERNATIONAL INC. ,  BAXTER HEALTHCARE S.A.

Inventor： WHITE, Jeff ,  CHEN, Ye ,  DING, Samuel ,  TITUS, Joel ,  ROHDE, Justin ,  MALIEKKAL, Shincy ,  COOPER, Kevin

IPC: G01N33/18 ,  G01N27/416

CPC classification number: A61M1/14 ,  A61M1/1656 ,  A61M1/1666 ,  A61M1/1668 ,  A61M1/1674 ,  B01D61/243 ,  B01D61/32 ,  B01D2311/2684 ,  C02F1/44 ,  C02F1/4674 ,  C02F2209/29 ,  C02F2305/02 ,  G01N27/4168 ,  G01N33/182 ,  Y02W10/33 ,  Y10T436/193333

Abstract: A system and method for determining a concentration of total chlorine in dialysis water are provided. The system comprises a main unit housing a KI/water sample chamber and a sodium sulfate chamber. A first electrode pair bridges the two chambers and generates tri-iodide proportional to the amount of total chlorine in the water sample. A second electrode pair in contact with fluid in the KI/water sample detects an amount of tri-iodide generated by the first electrode pair. The system is suitable for use in connection with, or for incorporation into, a water purification system for generating dialysis fluid, and may include a display that alerts the user to stop or prevent a hemodialysis treatment if the total chlorine level exceeds a predetermined level.

Abstract translation: 提供了一种用于测定透析水中总氯浓度的系统和方法。 该系统包括容纳KI /水样品室和硫酸钠室的主单元。 第一电极对桥接两个室，并产生与水样品中总氯量成比例的三碘化物。 与KI /水样品中的流体接触的第二电极对检测由第一电极对产生的三碘化物的量。 该系统适用于与用于生成透析液体的水净化系统相关联或用于并入用于产生透析液体的水净化系统，并且可以包括如果总氯水平超过预定水平则警告用户停止或防止血液透析治疗的显示器。

公开(公告)号：WO2014066254A1

公开(公告)日：2014-05-01

申请号：PCT/US2013/065951

申请日：2013-10-21

Applicant: BAXTER INTERNATIONAL INC. ,  BAXTER HEALTHCARE S.A.

Inventor： WHITE, Jeff ,  CHEN, Ye ,  DING, Samuel ,  TITUS, Joel ,  ROHDE, Justin ,  MALIEKKAL, Shincy ,  COOPER, Kevin

IPC: G01N33/18 ,  G01N27/416 ,  A61M1/16

CPC classification number: A61M1/1656 ,  A61M1/1603 ,  A61M1/1664 ,  A61M1/1668 ,  A61M2205/3327 ,  A61M2205/502 ,  A61M2205/75 ,  C02F1/50 ,  C02F2103/026 ,  G01N27/30 ,  G01N27/413 ,  G01N27/4168 ,  G01N33/0036 ,  Y02W10/33

Abstract: A system and method for determining a concentration of total chlorine in dialysis water are provided. The system comprises a main unit housing an iodide/water sample chamber and a reducing agent chamber. An electrode pair bridges the two chambers and generates tri-iodide proportional to the amount of total chlorine in the dialysis water. The electrode pair detects the amount of tri-iodide generated in proportion to the amount of active chloride in the dialysis water. The system is suitable for use in connection with, or for incorporation into, a water purification system for generating dialysis fluid, and may include a display that alerts the user to stop or prevent a hemodialysis treatment if the total chlorine level exceeds a predetermined level.

Abstract translation: 提供了一种用于测定透析水中总氯浓度的系统和方法。 该系统包括容纳碘化物/水样品室和还原剂室的主单元。 电极对桥接两个室，并产生与透析水中总氯量成比例的三碘化物。 电极对检测与透析水中的活性氯化物的量成比例地产生的三碘化物的量。 该系统适用于与用于生成透析液体的水净化系统相关联或用于并入用于产生透析液体的水净化系统，并且可以包括如果总氯水平超过预定水平则警告用户停止或防止血液透析治疗的显示器。

公开(公告)号：WO2009006493A2

公开(公告)日：2009-01-08

申请号：PCT/US2008/068952

申请日：2008-07-02

Applicant: BAXTER INTERNATIONAL INC. ,  BAXTER HEALTHCARE S.A. ,  SHAH, Dilip ,  REITZ, Douglas ,  DING, Samuel ,  DAHAN, Meir ,  CICCHELLO, Gino ,  BIEWER, John

Inventor： SHAH, Dilip ,  REITZ, Douglas ,  DING, Samuel ,  DAHAN, Meir ,  CICCHELLO, Gino ,  BIEWER, John

IPC: A61M1/16 ,  A61M1/28 ,  A61L2/18

CPC classification number: A61L2/183 ,  A61M1/166 ,  A61M1/1686 ,  A61M1/169 ,  A61M1/28 ,  A61M1/284 ,  A61M1/288 ,  A61M2202/0216 ,  A61M2205/12

Abstract: A medical fluid machine, such as a dialysis machine, includes a pump that pumps a medical fluid and sterile water or other disinfecting liquid, such as ozonated water, for flushing and reconditioning the medical fluid machine. The machine may also include a heater that heats the medical fluid or disinfecting solution in order to kill bacteria and other microorganisms that may contaminate the machine after use. Disinfecting the machine, and a disposable kit used with the machine, may allow re-use of the disposable within a reasonable amount of time after completion of the disinfecting procedure. Dialysate treated with ultra-violet light or water with low concentrations of ozone also helps make the disposable kits suitable for resuse.

Abstract translation: 诸如透析机的医疗流体机器包括泵，其泵送医用流体和无菌水或其它消毒液体，例如臭氧水，用于冲洗和修复医用流体机器。 该机器还可以包括加热器，其加热医用流体或消毒溶液，以杀死在使用后可能污染机器的细菌和其它微生物。 消毒机器和与机器一起使用的一次性套件可以在消毒过程完成之后在合理的时间内重新使用一次性装置。 用紫外光或含有低浓度臭氧的水处理的透析液也有助于使一次性套件适合重新使用。

公开(公告)号：EP1325074A2

公开(公告)日：2003-07-09

申请号：EP01977358.9

申请日：2001-09-28

Applicant: Baxter International Inc.

Inventor： YANG, Tahua ,  SHANG, Sherwin ,  WARREN, Joel ,  DING, Samuel ,  LING, Michael, T., K. ,  WOO, Lecon

IPC: C08L23/04 ,  A61L29/00

CPC classification number: A61L29/049 ,  C08L23/0815 ,  C08L2205/02 ,  C08L2314/06 ,  C08L23/04 ,  C08L2666/04

Abstract: The present invention provides a polymer blend for fabricating medical products. The blend has a first ethylene and α-olefin copolymer obtained using a single-site catalyst present in an amount by weight of from about 0 % to about 99 % by weight of the blend and having a melt flow index from about 0.1 g/10 min to about 5 g/10 min, a second ethylene and α-olefin copolymer obtained using a single-site catalyst and being present in an amount by weight of the blend from about 0 % to about 99 % and having a melt flow index from higher than about 5 g/10 min to about 20 g/10 min; and a third ethylene and α-olefin copolymer obtained using a single-site catalyst and being present in an amount by weight of the blend from about 0 % to about 99 % and having a melt flow index greater than about 20 g/10 min.

公开(公告)号：EP0605705B1

公开(公告)日：1997-05-21

申请号：EP93917174.0

申请日：1993-07-14

Applicant: BAXTER INTERNATIONAL INC.

Inventor： DING, Samuel ,  QIN, Chuan ,  RABINOW, Barrett

IPC: C08L101/00 ,  A61J1/00 ,  A61L33/00 ,  G02B1/04

CPC classification number: A61J1/05 ,  A61J1/10 ,  A61L33/062 ,  C08L23/08 ,  C08L33/12 ,  C08L53/02 ,  C08L67/02 ,  C08L69/00 ,  C08L71/02 ,  C08L77/00 ,  C08L101/00 ,  G02B1/043 ,  Y10T428/1352 ,  Y10T428/1383 ,  Y10T428/1397 ,  Y10T428/249991 ,  Y10T428/249992 ,  Y10T428/249993 ,  C08L2666/04 ,  C08L2666/14 ,  C08L2666/02

Abstract: A protein-compatible polymer blend made from a water-soluble polymer and a matrix polymer. The glass transition temperature of either the water-soluble polymer or the matrix polymer is greater than the application temperature, i.e., the temperature at which the protein-compatible polymer blend is being used.

公开(公告)号：EP0969884B1

公开(公告)日：2004-10-27

申请号：EP99902431.8

申请日：1999-01-25

Applicant: BAXTER INTERNATIONAL INC.

Inventor： WOO, Lecon ,  LING, Michael, T., K. ,  BALTEAU, Patrick ,  LO, Ying-Cheng ,  WOJNAROWSKI, Robert ,  SHAH, Ketan ,  HENAUT, Eric, J. ,  DING, Samuel ,  WESTPHAL, Stanley

IPC: A61L29/00

CPC classification number: A61L29/049 ,  C08F287/00 ,  C08L23/10 ,  C08L51/006 ,  C08L53/02 ,  C08L53/025 ,  C08L57/02 ,  Y10T428/139 ,  C08L23/12 ,  C08L2666/02 ,  C08L2666/04 ,  C08L2666/06

Abstract: A steam sterilizable monolayer medical tubing comprising a blend of a melt strength enhancing agent of a homopolymer or copolymer of polypropylene having a melt flow index of greater than 10 and in an amount of 1-10 % by weight and a second component selected from the group of (i) a selectively hydrogenated block copolymer of a vinyl aromatic hydrocarbon and a conjugated diene and (ii) a selectively hydrogenated block copolymer of a vinyl aromatic hydrocarbon and a conjugated diene to which has been grafted, an alpha, beta-olenfically unsaturated monocarboxylic or dicarboxylic acid reagent.

公开(公告)号：EP0969884A2

公开(公告)日：2000-01-12

申请号：EP99902431.8

申请日：1999-01-25

Applicant: BAXTER INTERNATIONAL INC.

Inventor： WOO, Lecon ,  LING, Michael, T., K. ,  BALTEAU, Patrick ,  LO, Ying-Cheng ,  WOJNAROWSKI, Robert ,  SHAH, Ketan ,  HENAUT, Eric, J. ,  DING, Samuel ,  WESTPHAL, Stanley

IPC: A61L29/00

CPC classification number: A61L29/049 ,  C08F287/00 ,  C08L23/10 ,  C08L51/006 ,  C08L53/02 ,  C08L53/025 ,  C08L57/02 ,  Y10T428/139 ,  C08L23/12 ,  C08L2666/02 ,  C08L2666/04 ,  C08L2666/06

Abstract: A steam sterilizable monolayer medical tubing comprising a blend of a melt strength enhancing agent of a homopolymer or copolymer of polypropylene having a melt flow index of greater than 10 and in an amount of 1-10 % by weight and a second component selected from the group of (i) a selectively hydrogenated block copolymer of a vinyl aromatic hydrocarbon and a conjugated diene and (ii) a selectively hydrogenated block copolymer of a vinyl aromatic hydrocarbon and a conjugated diene to which has been grafted, an alpha, beta-olenfically unsaturated monocarboxylic or dicarboxylic acid reagent.

公开(公告)号：EP0605705A1

公开(公告)日：1994-07-13

申请号：EP93917174.0

申请日：1993-07-14

Applicant: BAXTER INTERNATIONAL INC.

Inventor： DING, Samuel ,  QIN, Chuan ,  RABINOW, Barrett

IPC: A61J1 ,  A61L33 ,  C08L23 ,  C08L25 ,  C08L31 ,  C08L33 ,  C08L35 ,  C08L53 ,  C08L67 ,  C08L69 ,  C08L77 ,  C08L101 ,  G02B1 ,  C08L71

CPC classification number: A61J1/05 ,  A61J1/10 ,  A61L33/062 ,  C08L23/08 ,  C08L33/12 ,  C08L53/02 ,  C08L67/02 ,  C08L69/00 ,  C08L71/02 ,  C08L77/00 ,  C08L101/00 ,  G02B1/043 ,  Y10T428/1352 ,  Y10T428/1383 ,  Y10T428/1397 ,  Y10T428/249991 ,  Y10T428/249992 ,  Y10T428/249993 ,  C08L2666/04 ,  C08L2666/14 ,  C08L2666/02

Abstract: On décrit un mélange de polymères, compatible avec les protéines, constitué d'un polymère hydrosoluble et d'un polymère matriciel. La température de transition vitreuse de l'un comme de l'autre dépasse la température d'utilisation, c'est-à-dire celle à laquelle on utilise ce mélange de polymères.