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    MULTI-LAYER GAS-PERMEABLE CONTAINER FOR THE CULTURE OF ADHERENT AND NON-ADHERENT CELLS
    1.
    发明申请
    MULTI-LAYER GAS-PERMEABLE CONTAINER FOR THE CULTURE OF ADHERENT AND NON-ADHERENT CELLS 审中-公开
    多层气体渗透性容器，用于培养独立和非附着细胞

    公开(公告)号：WO1996013573A1

    公开(公告)日：1996-05-09

    申请号：PCT/US1995013943

    申请日：1995-10-27

    Applicant: BAXTER INTERNATIONAL INC.

    Inventor： BAXTER INTERNATIONAL INC. ,  SMITH, Sidney, T. ,  BACEHOWSKI, David, V. ,  KOLANKO, William ,  ROSENBAUM, Larry ,  SMITH, Stephen, L.

    IPC: C12M03/06

    CPC classification number: C12M23/14 ,  C12M23/24

    Abstract: A multi-layer, flexible, gas-permeable film (10) suitable for forming a cell culture container (20), the film (10) comprising a first layer (12) composed of a polystyrene having a thickness within the range of 0.0001 inch to about 0.0010 inch and, a second layer (14) adhered to the first layer (12) composed of a polymer material having a thickness within the range of 0.004 inch to about 0.025 inch.

    Abstract translation: 一种适用于形成细胞培养容器（20）的多层柔性透气薄膜（10），该薄膜（10）包括由厚度在0.0001英寸范围内的聚苯乙烯构成的第一层（12） 至约0.0010英寸，以及粘附到第一层（12）的第二层（14），所述第一层（12）由厚度在0.004英寸至约0.025英寸范围内的聚合物材料构成。

    MULTILAYER COEXTRUDED MATERIAL FOR MEDICAL GRADE PRODUCTS AND PRODUCTS MADE THEREFROM
    2.
    发明申请
    MULTILAYER COEXTRUDED MATERIAL FOR MEDICAL GRADE PRODUCTS AND PRODUCTS MADE THEREFROM 审中-公开
    医用级产品及其制品的多层复合材料

    公开(公告)号：WO1993015908A1

    公开(公告)日：1993-08-19

    申请号：PCT/US1993000594

    申请日：1993-01-22

    Applicant: BAXTER INTERNATIONAL INC.

    Inventor： BAXTER INTERNATIONAL INC. ,  PATEL, Indrajit ,  BOWERMAN, Harold ,  ROSENBAUM, Larry ,  MENNENOH, Rich ,  RYAN, Pat

    IPC: B32B27/08

    CPC classification number: A61J1/10 ,  A61J1/1406 ,  A61J1/1487 ,  A61L29/049 ,  A61M39/08 ,  B32B27/08 ,  C08K5/11 ,  C08L67/00 ,  C08L75/04 ,  C08L2666/06 ,  C08L2666/18 ,  C08L2666/02

    Abstract: The present invention provides a non-PVC, non-DEHP material that can be used for medical grade tubing. Additionally, the present invention provides medical grade tubing made from such a material. To this end, the present invention provides a medical grade tubing (14 and 20), comprising a multilayer coextruded structure including: a layer comprising a blend of polyurethane and polyester; and a layer comprising a blend chosen from the group consiting of: polypropylene, ethylenevinyl acetate, and polyurethane; polypropylene and styrene-ethylene-butylene-styrene; polypropylene, styrene-ethylene-butylene-styrene, and ethylenevinyl acetate; polypropylene, ethylenevinyl acetate, styrene-ethylene-butylene-styrene, and thermoplastic polyester elastomer; polypropylene, ethylenevinyl acetate, styrene-ethylene-butylene-styrene, thermoplastic polyester elastomer, and polyurethane; polyester, thermoplastic polyester elastomer, and polyurethane; polyester and polyurethane; and polypropylene, styrene-ethylene-butylene-styrene, and polyurethane.

    Abstract translation: 本发明提供了可用于医疗级管材的非PVC非DEHP材料。 另外，本发明提供了由这种材料制成的医用级管。 为此，本发明提供了一种医用级管（14和20），其包括多层共挤出结构，包括：包含聚氨酯和聚酯的共混物的层; 以及包含选自以下的混合物的层：聚丙烯，乙烯 - 乙酸乙烯酯和聚氨酯; 聚丙烯和苯乙烯 - 乙烯 - 丁烯 - 苯乙烯; 聚丙烯，苯乙烯 - 乙烯 - 丁烯 - 苯乙烯和乙烯 - 乙酸乙烯酯; 聚丙烯，乙烯乙酸乙烯酯，苯乙烯 - 乙烯 - 丁烯 - 苯乙烯和热塑性聚酯弹性体; 聚丙烯，乙烯乙酸乙烯酯，苯乙烯 - 乙烯 - 丁烯 - 苯乙烯，热塑性聚酯弹性体和聚氨酯; 聚酯，热塑性聚酯弹性体和聚氨酯; 聚酯和聚氨酯; 和聚丙烯，苯乙烯 - 乙烯 - 丁烯 - 苯乙烯和聚氨酯。

    MULTILAYERED POLYMER STRUCTURE
    3.
    发明申请
    MULTILAYERED POLYMER STRUCTURE 审中-公开
    多层聚合物结构

    公开(公告)号：WO2004039582A1

    公开(公告)日：2004-05-13

    申请号：PCT/US2002/034837

    申请日：2002-10-29

    Applicant: BAXTER INTERNATIONAL INC.

    Inventor： SMITH, Sidney, T. ,  ROSENBAUM, Larry ,  GIOVANETTO, Steven ,  NEBGEN, Gregg

    IPC: B32B27/32

    CPC classification number: B32B27/34 ,  B32B27/32 ,  B32B27/36 ,  Y10T428/31725 ,  Y10T428/31786

    Abstract: The present invention provides a multiple-layer structure for fabricating medical products. The multiple-layered structure has a first layer of a polyester; a second layer attached to the first layer, the second layer of an ethylene and α-olefin copolymer; and wherein the structure has a modulus of elasticity of less than about 60,000 psi.

    Abstract translation: 本发明提供用于制造医疗产品的多层结构。 多层结构具有第一层聚酯; 连接到第一层的第二层，第二层乙烯和α-烯烃共聚物; 并且其中所述结构具有小于约60,000psi的弹性模量。

    PERIMETER SEALS AND SEAM FOR MULTILAYER MATERIALS
    6.
    发明授权
    PERIMETER SEALS AND SEAM FOR MULTILAYER MATERIALS 有权
    PERIPHERIEABDICHTUNGEN UND NAHTFÜRMEHRSCHICHTIGE MATERIALIEN

    公开(公告)号：EP0963326B1

    公开(公告)日：2003-04-09

    申请号：EP98964099.0

    申请日：1998-12-18

    Applicant: BAXTER INTERNATIONAL INC.

    Inventor： SMITH, Sidney, T. ,  GIOVANETTO, Steven, H. ,  BUCHANAN, Bradley ,  ROSENBAUM, Larry

    IPC: B65D75/26 ,  B65D75/30 ,  B29C65/02 ,  B31B39/00

    CPC classification number: B65D75/26 ,  B29C65/02 ,  B29C65/04 ,  B29C65/08 ,  B29C65/16 ,  B29C65/18 ,  B29C66/1122 ,  B29C66/133 ,  B29C66/24244 ,  B29C66/43 ,  B29C66/4312 ,  B29C66/53262 ,  B29C66/71 ,  B29C66/723 ,  B29C66/8322 ,  B29L2031/7128 ,  B29L2031/7148 ,  B31B70/64 ,  B31B2155/00 ,  B31B2170/20 ,  B29K2025/06 ,  B29K2023/086 ,  B29K2023/00

    Abstract: A container (10) is disclosed comprising a first sidewall (12) having a first layer (104) and a second layer (102). The second layer (102) overlaps a portion of the first layer (104) to define an overlap area (106). A sealing flange (108) extends from the first layer (104) outward of the overlap area (106). A second sidewall (14) is connected to the first sidewall (12) along the sealing flange (108) to define an inner chamber (23) therebetween. The second sidewall (14) and the sealing flange (108) define a first layered structure (120) having a first number of layers along the sealing flange (108). The overlap area (106) and the second sidewall (14) define a second layered structure (122) having a second number of layers. The second number of layers is greater than the first number of layers. The container (10) is sealed by positioning peripheral edges of the first and second sidewalls (12, 14) into registration so that the overlap area (106) is substantially centrally disposed over the second sidewall (14) and applying sealing energy to the first number of layers to define a peripheral seam. Another container (200) suitable for medical uses comprises a first planar member (218), a second planar member (222), a first seam (224) and a second seam (226). The first planar member (218) is of a multi-layered polymeric material and further comprises a first substrate (238) and a first layer (246). The first layer (246) is disposed on a portion of the first substrate (238) to separately define a first overlap area (258) and an adjacent first peripheral flange (262). The second planar member (222) is of a multi-layered polymeric material. The first seam (224) attaches a portion of the first overlap area (258) to the second planar member (222). The second seam (226) is spaced from the first seam (224) and attaches a portion of the first peripheral flange (262) to the second planar member (222).

    Abstract translation: 提供具有第一和第二侧壁的容器。 第一侧壁包括第一层和第二层，其中第二层与第一层的一部分重叠以限定重叠区域。 密封凸缘从重叠区域向外延伸，第二侧壁沿着密封凸缘连接到第一侧壁，以在它们之间限定内部腔室。 第二侧壁和密封凸缘限定了沿着密封凸缘包括多个层的第一分层结构。 重叠区域和第二侧壁限定了具有比第一分层结构多的层的第二分层结构。 通过将第一和第二侧壁的外围边缘定位成对准来使容器密封，使得重叠区域居中地设置在第二侧壁上方。 然后将密封能量施加到第一分层结构以限定外围接缝。

    PERIMETER SEALS AND ENCAPSULATED SEAM FOR MULTILAYER MATERIALS
    7.
    发明公开
    PERIMETER SEALS AND ENCAPSULATED SEAM FOR MULTILAYER MATERIALS 有权
    EIPEERSABDICHTUNGEN UNDEHERIEABDICHTUNGEN UND EINGEKAPSELTE NAHTFÜRMEHRSCHICHTIGE MATERIALIEN

    公开(公告)号：EP0963326A1

    公开(公告)日：1999-12-15

    申请号：EP98964099.0

    申请日：1998-12-18

    Applicant: BAXTER INTERNATIONAL INC.

    Inventor： SMITH, Sidney, T. ,  GIOVANETTO, Steven, H. ,  BUCHANAN, Bradley ,  ROSENBAUM, Larry

    IPC: B65D75 ,  B29C65 ,  B31B1 ,  B31B19 ,  B31B39

    CPC classification number: B65D75/26 ,  B29C65/02 ,  B29C65/04 ,  B29C65/08 ,  B29C65/16 ,  B29C65/18 ,  B29C66/1122 ,  B29C66/133 ,  B29C66/24244 ,  B29C66/43 ,  B29C66/4312 ,  B29C66/53262 ,  B29C66/71 ,  B29C66/723 ,  B29C66/8322 ,  B29L2031/7128 ,  B29L2031/7148 ,  B31B70/64 ,  B31B2155/00 ,  B31B2170/20 ,  B29K2025/06 ,  B29K2023/086 ,  B29K2023/00

    Abstract: A container (10) is disclosed comprising a first sidewall (12) having a first layer (104) and a second layer (102). The second layer (102) overlaps a portion of the first layer (104) to define an overlap area (106). A sealing flange (108) extends from the first layer (104) outward of the overlap area (106). A second sidewall (14) is connected to the first sidewall (12) along the sealing flange (108) to define an inner chamber (23) therebetween. The second sidewall (14) and the sealing flange (108) define a first layered structure (120) having a first number of layers along the sealing flange (108). The overlap area (106) and the second sidewall (14) define a second layered structure (122) having a second number of layers. The second number of layers is greater than the first number of layers. The container (10) is sealed by positioning peripheral edges of the first and second sidewalls (12, 14) into registration so that the overlap area (106) is substantially centrally disposed over the second sidewall (14) and applying sealing energy to the first number of layers to define a peripheral seam. Another container (200) suitable for medical uses comprises a first planar member (218), a second planar member (222), a first seam (224) and a second seam (226). The first planar member (218) is of a multi-layered polymeric material and further comprises a first substrate (238) and a first layer (246). The first layer (246) is disposed on a portion of the first substrate (238) to separately define a first overlap area (258) and an adjacent first peripheral flange (262). The second planar member (222) is of a multi-layered polymeric material. The first seam (224) attaches a portion of the first overlap area (258) to the second planar member (222). The second seam (226) is spaced from the first seam (224) and attaches a portion of the first peripheral flange (262) to the second planar member (222).

    Abstract translation: 提供具有第一和第二侧壁的容器。 第一侧壁包括第一层和第二层，其中第二层与第一层的一部分重叠以限定重叠区域。 密封凸缘从重叠区域向外延伸，第二侧壁沿着密封凸缘连接到第一侧壁，以在它们之间限定内部腔室。 第二侧壁和密封凸缘限定了沿着密封凸缘包括多个层的第一分层结构。 重叠区域和第二侧壁限定了具有比第一分层结构多的层的第二分层结构。 通过将第一和第二侧壁的外围边缘定位成对准来使容器密封，使得重叠区域居中地设置在第二侧壁上方。 然后将密封能量施加到第一分层结构以限定外围接缝。

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