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    Probe photometer with fluid sensing device
    2.
    发明授权
    Probe photometer with fluid sensing device 失效
    具有流体感应装置的探头光电测量仪

    公开(公告)号：US3727066A

    公开(公告)日：1973-04-10

    申请号：US3184770

    申请日：1970-05-01

    Applicant: BAXTER LABORATORIES INC

    Inventor： LOUDERBACK A ,  OWEN R

    IPC: G01N21/85 ,  G01N21/26

    CPC classification number: G01N21/8507

    Abstract: The invention is concerned with an improved probe-type of photometer, the probe of which may be inserted directly into a liquid or gas, to measure the light transmission through the fluid; and which may be used, for example, for spectrophotometric, turbidity, colorimetric, densitometer, or other measurements.

    Abstract translation: 本发明涉及一种改进的光度计的探针型，其探针可以直接插入液体或气体中，以测量通过流体的光透射; 并且其可以用于例如分光光度，浊度，比色，密度计或其它测量。

    Diagnostic test for sickle-cell
    3.
    发明授权
    Diagnostic test for sickle-cell 失效
    SICKLE CELL诊断测试

    公开(公告)号：US3847545A

    公开(公告)日：1974-11-12

    申请号：US25458472

    申请日：1972-05-18

    Applicant: BAXTER LABORATORIES INC

    Inventor： SHANBROM E ,  LOUDERBACK A

    IPC: G01N33/72 ,  G01N21/06 ,  G01N33/16

    CPC classification number: G01N33/52 ,  G01N33/5091 ,  G01N33/721

    Abstract: A microcapillary method for the diagnosis of sickle-cell disease in which a sample of unclotted blood is mixed with a reagent comprising phosphate buffer containing a non-ionic surfactant having high water solubility, a hemolyzing agent and a reducing agent, and the reaction results observed macroscopically for turbidity and then a microcapillary sample thereof observed macroscopically for color characteristics.

    Abstract translation: 用于诊断镰状细胞病的微毛细管法，其中将未切开血液的样品与包含含有具有高水溶性的非离子表面活性剂的磷酸盐缓冲液，溶血剂和还原剂的试剂混合，并观察反应结果 在宏观上用于浊度，然后宏观地观察微毛细管样品的颜色特性。

    Blood serum analytical control standard
    6.
    发明授权
    Blood serum analytical control standard 失效
    血清血清分析控制标准

    公开(公告)号：US3728226A

    公开(公告)日：1973-04-17

    申请号：US3728226D

    申请日：1970-06-01

    Applicant: BAXTER LABORATORIES INC

    Inventor： LOUDERBACK A

    IPC: G01N33/96 ,  C12K1/04

    CPC classification number: G01N33/96 ,  G01N2496/05 ,  G01N2496/80 ,  Y10T436/106664

    Abstract: A CONTROL STANDARD FOR THE ANALYTICAL DETERMINATION OF MULTIPLE BLOOD SERUM COMPOUNDS CONSISTING OF A MIXTURE OF AT LEAST THREE OF SAID BLOOD SERUM COMPONENTS HAVING THEIR RESPECTIVE CONCENTRATIONS INDISCRIMINATELY PREDETERMINED BY RANDOM SELECTION FROM THE RANGE OF LOWEST TO HIGHEST LEVELS OF EACH SAID COMPONENT ESTABLISHED BY INSTRUMENTATION PARAMETERS AND CLINICAL SIGNIFICANCE.

    SICKLE-CELL DIAGNOSTIC TEST
    7.
    发明专利
    SICKLE-CELL DIAGNOSTIC TEST 未知

    公开(公告)号：ZA731900B

    公开(公告)日：1973-12-19

    申请号：ZA731900

    申请日：1973-03-19

    Applicant: BAXTER LABORATORIES INC

    Inventor： LOUDERBACK A ,  YOUHNE Y ,  FONTANA A

    IPC: G01N33/72 ,  A61K

    Abstract: 1377346 Diagnostic agent for detecting sicklecell disease BAXTER LABORATORIES Inc 26 March 1973 [24 March 1972] 14443/73 Heading G1B A reagent kit for use in testing blood for sicklecell disease and for distinguishing between sicklecell anemia and sickle-cell trait comprises (a) an aqueous buffer solution having a pH of from 7 to 7À5 and containing, per 100 ml of solution, from 21 to 35 grams of (NH 4 ) 2 SO 4 and from 0À5 to 2À0 grams of K 2 HPO 4 , (b) a hemolyzing agent, for example saponin, and (c) a reducing agent, for example sodium dithionite. The hemolyzing agent and the reducing agent may be in powdered form. Reagent solution prepared by mixing the contents of such kit may contain, per 100 ml of solution, from 0À01 to 2 grams of hemolyzing agent and from 0À01 to 2 grams of reducing agent. A sample of unclotted blood is mixed with a predetermined amount of reagent solution, the mixture being observed visually both before and after centrifuging. A translucent solution before centrifuging indicates normal (AA) hemoglobin whereas a turbid solution indicates either sickle-cell trait (AS) hemoglobin or sickle-cell anemia (SS) hemoglobin; a small amount of white precipitate after centrifuging indicates normal hemoglobin whereas a pink solution with red precipitate indicates sickle-cell hemoglobin and a yellow solution with red precipitate indicates sickle-cell anemia hemoglobin. The buffer solution additionally may contain a redox dye, for example methylene blue or basic fuchsin, for indicating decomposition of sodium dithionite reducing agent.

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