公开(公告)号：WO9511912A3

公开(公告)日：1995-06-08

申请号：PCT/US9412437

申请日：1994-10-28

Applicant: BECKMAN INSTRUMENTS INC

Inventor： COASSIN PETER J ,  MATSON ROBERT S ,  RAMPAL JANG B

IPC: G01N33/53 ,  A61K38/00 ,  A61K39/44 ,  B01J19/00 ,  C07H21/00 ,  C07H21/04 ,  C07K1/04 ,  C07K7/06 ,  C07K7/08 ,  C08B37/00 ,  C12N15/09 ,  C12Q1/68 ,  C40B40/06 ,  C40B40/10 ,  C40B40/12 ,  G01N33/543 ,  G01N33/545 ,  G01N33/566 ,  G01N37/00

CPC classification number: C07H21/00 ,  B01J19/0046 ,  B01J2219/00497 ,  B01J2219/00527 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/00612 ,  B01J2219/00626 ,  B01J2219/00659 ,  B01J2219/0072 ,  B01J2219/00722 ,  B01J2219/00725 ,  B01J2219/00729 ,  B01J2219/00731 ,  C07K1/042 ,  C12Q1/6834 ,  C12Q1/6869 ,  C40B40/06 ,  C40B40/10 ,  C40B40/12 ,  G01N33/54353 ,  Y10T436/143333

Abstract: Disclosed herein are surface activated, organic polymers useful for biopolymer synthesis. Most preferably, aminated biaxially oriented polypropylene is used for the synthesis of oligonucleotides thereto, and these devices are most preferably utilized for genetic analysis of patient samples.

公开(公告)号：WO9509176A1

公开(公告)日：1995-04-06

申请号：PCT/US9309294

申请日：1993-09-28

Applicant: BECKMAN INSTRUMENTS INC

Inventor： COASSIN PETER J ,  MATSON ROBERT S ,  RAMPAL JANG B

IPC: C07H21/00 ,  C08F8/00 ,  C08F8/32 ,  C12Q1/68 ,  C07K1/04 ,  C08F8/30 ,  C08J3/28 ,  G01N33/68

CPC classification number: C07H21/00 ,  C08F8/30 ,  C08F8/32 ,  C12Q1/6827 ,  C12Q1/6834 ,  C08F110/06

Abstract: Disclosed herein are surface activated, organic polymers useful for biopolymer synthesis. Most preferably, aminated polypropylene is used for the synthesis of oligonucleotides thereto, and these devices are most preferably utilized for genetic analysis of patient samples.

Abstract translation: 本文公开了可用于生物聚合物合成的表面活化的有机聚合物。 最优选地，胺化聚丙烯用于合成寡核苷酸，并且这些装置最优选用于患者样品的遗传分析。

公开(公告)号：AU671688B2

公开(公告)日：1996-09-05

申请号：AU5294493

申请日：1993-09-28

Applicant: BECKMAN INSTRUMENTS INC

Inventor： COASSIN PETER J ,  MATSON ROBERT S ,  RAMPAL JANG B

IPC: C07H21/00 ,  C08F8/00 ,  C08F8/32 ,  C12Q1/68 ,  C12Q1/6827 ,  C12Q1/6834 ,  C07K1/04 ,  C08F8/30 ,  C07H3/00 ,  C08J7/12

Abstract: Disclosed herein are surface activated, organic polymers useful for biopolymer synthesis. Most preferably, aminated polypropylene is used for the synthesis of oligonucleotides thereto, and these devices are most preferably utilized for genetic analysis of patient samples.

公开(公告)号：AU2360195A

公开(公告)日：1995-11-29

申请号：AU2360195

申请日：1995-04-24

Applicant: BECKMAN INSTRUMENTS INC ,  CHARLES THOMAS CASKEY

Inventor： CASKEY CHARLES THOMAS ,  MATSON ROBERT S ,  COASSIN PETER J ,  RAMPAL JANG B

IPC: C12Q1/68 ,  C12Q1/6827 ,  C12Q1/6837 ,  C12Q1/6874

Abstract: A solid support based hybridization assay is provided which allows for the systematic and reproducible analysis of repeat and tandem repeat oligonucleotide sequences of DNA and RNA by hybridization to a reverse dot blot array comprising strings of such repeats complementary to those found in particular nucleic acid targets (e.g., analyte PCR product). An addressable library (i.e., an indexed set) of complementary repeats is synthesized on a suitable support. Preferably, the support comprises a low fluorescent background support, thereby facilitating the use of non-radioisotopic modes of detection (such as fluorescence or chemiluminescence); particularly suitable in this regard is an aminated polypropylene support or similar material. Preferred arrays permit screening of DNA and RNA samples for complete sets of particular types of nucleotide repeat sequences (e.g., all nucleotide doublet or triplet repeats).

公开(公告)号：AU5294493A

公开(公告)日：1995-04-18

申请号：AU5294493

申请日：1993-09-28

Applicant: BECKMAN INSTRUMENTS INC

Inventor： COASSIN PETER J ,  MATSON ROBERT S ,  RAMPAL JANG B

IPC: C07H21/00 ,  C08F8/00 ,  C08F8/32 ,  C12Q1/68 ,  C12Q1/6827 ,  C12Q1/6834 ,  C07K1/04 ,  G01N33/68 ,  C08F8/30 ,  C08J3/28

Abstract: Disclosed herein are surface activated, organic polymers useful for biopolymer synthesis. Most preferably, aminated polypropylene is used for the synthesis of oligonucleotides thereto, and these devices are most preferably utilized for genetic analysis of patient samples.

公开(公告)号：CA2167589A1

公开(公告)日：1995-04-06

申请号：CA2167589

申请日：1993-09-28

Applicant: BECKMAN INSTRUMENTS INC

Inventor： COASSIN PETER J ,  MATSON ROBERT S ,  RAMPAL JANG B

IPC: C07H21/00 ,  C07K1/04 ,  C12Q1/68

Abstract: Disclosed herein are surface activated, organic polymers useful for biopolymer synthesis. Most preferably, aminated polypropylene is used for the synthesis of oligonucleotides thereto, and these devices are most preferably utilized for genetic analysis of patient samples.