Incident light redistribution to compensate for radial gradient in detector

    公开(公告)号:AU2006247825B2

    公开(公告)日:2010-12-09

    申请号:AU2006247825

    申请日:2006-05-09

    Abstract: Nonuniformities in the efficiency of detection of individual fluorescing reaction mixtures in a well plate with a two-dimensional array well array are corrected. The nonuniformities arise both from the stimulation pattern and the detection pattern, and are corrected by adding additional segments to a pair of segmented mirrors. The additional segments are oriented to direct light to the outermost reaches (i.e., the four corners) of the array and thereby produce a stimulation pattern that has a greater intensity in the outermost regions. This compensates for a radial decline in the efficiency of the detector in detecting the emissions from the well plate, the radial decline being an artifact of systems that utilize CCDs or similar components as detectors.

    INCIDENT LIGHT REDISTRIBUTION TO COMPENSATE FOR RADIAL GRADIENT IN DETECTOR
    8.
    发明申请
    INCIDENT LIGHT REDISTRIBUTION TO COMPENSATE FOR RADIAL GRADIENT IN DETECTOR 审中-公开
    偶然的光重新分配来补偿检测器中的径向梯度

    公开(公告)号:WO2006124435A3

    公开(公告)日:2008-01-03

    申请号:PCT/US2006018018

    申请日:2006-05-09

    CPC classification number: G02B27/0927 G02B27/0977

    Abstract: Nonuniformities in the efficiency of detection of individual fluorescing reaction mixtures in a well plate with a two-dimensional array well array are corrected. The nonuniformities arise both from the stimulation pattern and the detection pattern, and are corrected by adding additional segments to a pair of segmented mirrors. The additional segments are oriented to direct light to the outermost reaches (i.e., the four corners) of the array and thereby produce a stimulation pattern that has a greater intensity in the outermost regions. This compensates for a radial decline in the efficiency of the detector in detecting the emissions from the well plate, the radial decline being an artifact of systems that utilize CCDs or similar components as detectors.

    Abstract translation: 校正具有二维阵列阵列的孔板中各个荧光反应混合物的检测效率的不均匀性。 不均匀性从刺激图案和检测图案都出现,并且通过将附加段添加到一对分段镜来校正。 另外的部分被定向以将光引导到阵列的最外层(即,四个角),从而产生在最外区域具有更大强度的刺激图案。 这补偿了检测器在检测井板发射时的效率的径向下降,径向下降是利用CCD或类似部件作为检测器的系统的假象。

    INCIDENT LIGHT REDISTRIBUTION TO COMPENSATE FOR RADIAL GRADIENT IN DETECTOR

    公开(公告)号:CA2608000C

    公开(公告)日:2013-02-19

    申请号:CA2608000

    申请日:2006-05-09

    Abstract: Nonuniformities in the efficiency of detection of individual fluorescing reaction mixtures in a well plate with a two-dimensional array well array are corrected. The nonuniformities arise both from the stimulation pattern and the detection pattern, and are corrected by adding additional segments to a pair of segmented mirrors. The additional segments are oriented to direct light to the outermost reaches (i.e., the four corners) of the array and thereby produce a stimulation pattern that has a greater intensity in the outermost regions. This compensates for a radial decline in the efficiency of the detector in detecting the emissions from the well plate, the radial decline being an artifact of systems that utilize CCDs or similar components as detectors.

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