公开(公告)号：WO2007118049A2

公开(公告)日：2007-10-18

申请号：PCT/US2007065775

申请日：2007-04-02

Applicant: BIO RAD LABORATORIES ,  CHU DANIEL Y ,  PATT PAUL J

Inventor： CHU DANIEL Y ,  PATT PAUL J

IPC: A61N5/00

CPC classification number: G01N21/253 ,  B01L7/52 ,  G01N2201/101

Abstract: Translational motion of a scanning head relative to a planar target, or vice versa, is achieved by a belt and pulley system with a counterweight that is also driven by a belt and pulley system at the same speed but in the opposite direction as the scanning head. The components and belt and pulley system are oriented such that all moving components remain on one side of the target and remain so during their entire range of movement.

Abstract translation: 扫描头相对于平面目标的平移运动，反之亦然，通过皮带和皮带轮系统来实现，该带和滑轮系统具有配重，该配重也由带和皮带轮系统以与扫描头相同的速度但与之相反的方向驱动 。 部件和皮带轮系统被定向成使得所有移动部件保持在目标的一侧并且在其整个移动范围内保持。

公开(公告)号：DK2004291T3

公开(公告)日：2013-06-03

申请号：DK07759950

申请日：2007-04-02

Applicant: BIO RAD LABORATORIES

Inventor： CHU DANIEL Y ,  PATT PAUL J

IPC: G01N21/64

公开(公告)号：ES2401905T3

公开(公告)日：2013-04-25

申请号：ES07759950

申请日：2007-04-02

Applicant: BIO RAD LABORATORIES

Inventor： CHU DANIEL Y ,  PATT PAUL J

IPC: G01N21/64

Abstract: Un sistema de barrido para el barrido de un objetivo (12, 21, 31, 32) plano, en el que dicho objetivo (12, 21, 31,32) plano y una cabeza (11, 23, 33, 34) de barrido se definen como miembros de un par de barrido, siendo uno dedichos miembros móvil y siendo el otro fijo, comprendiendo dicho sistema de barrido: unos medios (15, 22) de correa sobre los cuales están montados dicho miembro móvil del par de barrido yun contrapeso (18, 25) en emplazamientos tales que la rotación de dichos medios (15, 22) de correaproduce el movimiento síncrono de dicho miembro móvil del par de barrido y dicho contrapeso (18, 25) endirecciones opuestas a lo largo de las trayectorias lineales de movimiento paralelas a y sobre un ladocomún de dicho miembro fijo del par de barrido; y unos medios (13) de accionamiento para hacer rotar dichos medios de correa para producir dichomovimiento síncrono; en el que (i) dicha trayectoria lineal de movimiento de dicho miembro móvil del par debarrido se produce entre dicha trayectoria lineal de movimiento de dicho contrapeso (18, 25) y dichomiembro fijo del par de barrido, o (ii) dichos medios (15, 22) de correa son un par de correas (15, 22)continuas con dicho miembro móvil de barrido montado sobre una de dichas correas (15, 22) y dichocontrapeso (18, 25) montado sobre la otra de dichas correas (15, 22) y dichos medios (13) deaccionamiento están comprendidos por una sola polea de sincronización que arrastra ambas correas (15,22) y una sola polea (14) loca que arrastra ambas correas (15, 22), o bien (i) y (ii) al mismo tiempo.

公开(公告)号：SG178555A1

公开(公告)日：2012-03-29

申请号：SG2012013009

申请日：2010-08-30

Applicant: BIO RAD LABORATORIES

Inventor： MCCOLLUM TOM ,  PATT PAUL ,  SHEN FRANK ,  CHU DANIEL Y ,  FLORY DON ,  GRIFFIN MIKE ,  HENG XIN ,  HEFNER ELI

Abstract: Biological cells in a liquid suspension are counted in an automated cell counter that focuses an image of the suspension on a digital imaging sensor that contains at least 4,000,000 pixels each having an area of 2 x 2 μm or less and that images a field of view of at least 3 mm2. The sensor enables the counter to compress the optical components into an optical path of less than 20 cm in height when arranged vertically with no changes in direction of the optical path as a whole, and the entire instrument has a footprint of less than 300 cm2. Activation of the light source, automated focusing of the sensor image, and digital cell counting are all initiated by the simple insertion of the sample holder into the instrument. The suspension is placed in a sample chamber in the form of a slide that is shaped to ensure proper orientation of the slide in the cell counter.

公开(公告)号：CA2715292A1

公开(公告)日：2009-08-20

申请号：CA2715292

申请日：2009-02-13

Applicant: BIO RAD LABORATORIES

Inventor： CEREMONY JEFFRY MARK ,  CHU DANIEL Y ,  DOSHI DEEPAK KUMAR ,  RUMBAOA RHOEL ,  LORING DENNIS WAYNE ,  PATT PAUL J ,  BALDWIN CLIFF

IPC: C12M1/38 ,  B01L7/00

Abstract: A thermal cycling instrument for PCR and other reactions performed on multiple samples with temperature changes between sequential stages in the reaction procedure is supplied with a thermal block to provide rapid changes and close control over the temperature in each sample vessel and a pressure plate incorporated into a motorized lid that detects anomalies in the reaction vessels or in their positioning over the thermal block, and automatically adjusts the plate position to achieve an even force distribution over the sample vessels.

公开(公告)号：GB2273783A

公开(公告)日：1994-06-29

申请号：GB9320520

申请日：1993-10-05

Applicant: BIO RAD LABORATORIES

Inventor： CHU DANIEL Y ,  MARDIS ELAINE R

IPC: B01D57/02 ,  C25B7/00 ,  G01N27/447 ,  G01N27/453

公开(公告)号：WO2007053244A3

公开(公告)日：2009-05-07

申请号：PCT/US2006036553

申请日：2006-09-19

Applicant: BIO RAD LABORATORIES ,  PATT PAUL J ,  CHU DANIEL Y ,  CEREMONY JEFFRY

Inventor： PATT PAUL J ,  CHU DANIEL Y ,  CEREMONY JEFFRY

IPC: H02K41/00 ,  H02K1/00 ,  H02K17/00 ,  H02K33/00 ,  H02K35/00

CPC classification number: H02K33/18

Abstract: A moving coil actuator that moves in a rapid back-and-forth motion is constructed with a magnet assembly that concentrates the magnetic flux in a region of limited length and with a coiled electric conductor that includes two separated regions of densely wound coil, the assembly and conductor arranged such that only one of the coil regions resides in a concentrated flux region at either end of the actuator stroke. This is achieved with either a single region of concentrated flux or two spatially separated regions of concentrated flux. In either case, the force constant, i.e., the motor force generated in each coil per unit of current through the coil, is non-linear, with a maximal force at each end of the stroke and a minimal force at the stroke mid-point. The result is an efficient use of the electric current and relatively small amounts of materials of construction, and accordingly less weight for the actuator to carry during its travel and its changes of direction.

Abstract translation: 以快速往复运动运动的运动线圈致动器由磁体组件构成，该磁体组件将磁通集中在有限长度的区域中，并且具有卷绕的电导体，该线圈电导体包括密集卷绕的线圈的两个分开的区域，该组件 并且导体布置成使得仅一个线圈区域驻留在致动器行程的任一端处的集中通量区域中。 这可以通过浓缩通量的单个区域或两个空间上分离的浓度通量的区域来实现。 在任一情况下，力常数即在每个线圈中每单位电流通过线圈产生的电机力是非线性的，在行程的每个末端具有最大的力，并且在行程中点处具有极小的力 。 结果是有效地使用电流和相对少量的结构材料，并且因此在执行器行进期间携带的重量以及其方向的变化更小。

公开(公告)号：WO2007064398A3

公开(公告)日：2007-10-04

申请号：PCT/US2006038436

申请日：2006-09-29

Applicant: BIO RAD LABORATORIES ,  CHU DANIEL Y

Inventor： CHU DANIEL Y

IPC: G05B1/06

CPC classification number: H02K41/0356

Abstract: A moving coil actuator contains a magnet assembly that is movable to shift the range of motion of the coil. The magnet assembly moves between two or more positions along a path of travel that is parallel to the path of travel of the reciprocating motion of the coil. With this feature, the width of an area scanned by a scanning head affixed to the coil can be increased by multiples allowing a simple moving coil actuator to be used for any scanning width.

Abstract translation: 运动线圈致动器包括可移动以移动线圈的运动范围的磁体组件。 磁体组件沿着平行于线圈的往复运动的行进路径的行进路径在两个或更多个位置之间移动。 利用这个特征，由固定在线圈上的扫描头扫描的区域的宽度可以增加多倍，从而允许使用简单的移动线圈致动器用于任何扫描宽度。

公开(公告)号：CA2772376C

公开(公告)日：2019-10-22

申请号：CA2772376

申请日：2010-08-30

Applicant: BIO RAD LABORATORIES

Inventor： MCCOLLUM TOM ,  PATT PAUL ,  SHEN FRANK ,  CHU DANIEL Y ,  FLORY DON ,  GRIFFIN MIKE ,  HENG XIN ,  HEFNER ELI

IPC: C12M1/34 ,  C12Q1/06 ,  G06M11/00

Abstract: Biological cells in a liquid suspension are counted in an automated cell counter that focuses an image of the suspension on a digital imaging sensor that contains at least 4,000,000 pixels each having an area of 2 x 2 µm or less and that images a field of view of at least 3 mm2. The sensor enables the counter to compress the optical components into an optical path of less than 20 cm in height when arranged vertically with no changes in direction of the optical path as a whole, and the entire instrument has a footprint of less than 300 cm2. Activation of the light source, automated focusing of the sensor image, and digital cell counting are all initiated by the simple insertion of the sample holder into the instrument. The suspension is placed in a sample chamber in the form of a slide that is shaped to ensure proper orientation of the slide in the cell counter.

公开(公告)号：CA2630431C

公开(公告)日：2012-11-20

申请号：CA2630431

申请日：2006-09-29

Applicant: BIO RAD LABORATORIES

Inventor： CHU DANIEL Y

IPC: G05B1/06

Abstract: A moving coil actuator contains a magnet assembly that is movable to shift the range of motion of the coil. The magnet assembly moves between two or more positions along a path of travel that is parallel to the path of travel of the reciprocating motion of the coil. With this feature, the width of an area scanned by a scanning head affixed to the coil can be increased by multiples allowing a simple moving coil actuator to be used for any scanning width.