公开(公告)号：CA2713093A1

公开(公告)日：2009-07-16

申请号：CA2713093

申请日：2009-01-06

Applicant: BIO RAD LABORATORIES

Inventor： SNYDER MARK A ,  BAKER KEN ,  MORAN CHRISTOPHER

IPC: F15B15/28 ,  B01D53/02 ,  G01D5/02

Abstract: In an axial-flow cylindrical preparative chromatography column that utilizes a piston to close off the top of the resin space inside the column and thereby eliminate void spaces at the top of the resin, one or more proximity detectors are incorporated in the piston head to either generate a signal indicating the proximity of the piston had to the resin, or to collect a signal, such as a optical signal, emitted from the resin. The value of the signal or any change in the signal is compared to a threshold value to ascertain when the piston head is in proximity to the resin so that the motion of the piston toward the resin can be halted before contact pressure from the piston head damages the resin.

公开(公告)号：EP2747864A4

公开(公告)日：2015-04-15

申请号：EP12825026

申请日：2012-08-23

Applicant: BIO RAD LABORATORIES

Inventor： IOVANNI ROBERT ,  GORDON ALEC ,  AVARBOCK BOB ,  BLAND WAYNE ,  PRICE GLENN ,  BAKER KEN ,  MAVANDADI FARAH ,  SHULTZ CHRISTOF

IPC: G01N30/88

CPC classification number: G01N30/38 ,  B01D15/18 ,  G01N30/465 ,  G01N30/468 ,  G01N30/88 ,  G01N2030/8804 ,  G01N2030/8881 ,  G01N2035/00326 ,  G05B15/02 ,  G05D7/0617

Abstract: Valves, pumps, detectors, sample loops, fraction collectors and the like are individually incorporated into modules that are mountable in interchangeable manner at individual mounting sites on a base unit which also supports one or more chromatography columns. Each module includes fluid connections to other modules and a microcontroller joining the module to a computed and monitor through an electronic connector at each mounting site. The fluid connections between the modules and the column(s) are removed from the electronic connections and accessible to the user. A software platform recognizes the modules and their locations, coordinates fluid connections between the modules, and provides a variety of control, monitoring, data generating and data processing functions to generate chromatographic data.

Abstract translation: 阀，泵，检测器，样品回路，馏分收集器等分别并入模块中，模块可以以可互换的方式安装在也支撑一个或多个色谱柱的基本单元上的各个安装位置。 每个模块包括与其他模块的流体连接，以及通过每个安装位置处的电子连接器将模块连接到计算机和监视器的微控制器。 模块和列之间的流体连接从电子连接中移除并可由用户访问。 软件平台识别模块及其位置，协调模块之间的流体连接，并提供各种控制，监控，数据生成和数据处理功能，以生成色谱数据。

公开(公告)号：EP2232084A4

公开(公告)日：2013-02-13

申请号：EP09700954

申请日：2009-01-06

Applicant: BIO RAD LABORATORIES

Inventor： SNYDER MARK A ,  BAKER KEN ,  MORAN CHRISTOPHER

IPC: B01D15/10 ,  B01D15/20 ,  B01D15/22 ,  G01D5/22 ,  G01D5/34

CPC classification number: G01D5/2291 ,  B01D15/10 ,  B01D15/20 ,  B01D15/22 ,  G01D5/34