公开(公告)号：ES2326312T3

公开(公告)日：2009-10-07

申请号：ES02808314

申请日：2002-12-25

Applicant: BIO RAD LABORATORIES

Inventor： RAN BOAZ ,  NOTCOVICH ARIEL G ,  LIPSON ARIEL ,  NIMRI SHAY ,  LIPSON STEPHEN G ,  LIPSON DORON

IPC: G01N21/55 ,  G01J3/30 ,  G01N21/05

Abstract: Un sistema de iluminación para iluminar una superficie de sensor SPR (32) que tiene formada en la misma una capa conductora (33, 142, 152, 154), comprendiendo el sistema de iluminación: Una disposición (132) de fuentes de luz (26, 134); Un colimador (46) que dirige la luz desde cada fuente de luz (26, 134) en un haz colimado de luz de manera que la luz es incidente sobre la superficie de sensor (32); y Un controlador de fuentes de luz controlable para apagar y encender una fuente de luz (26, 134) en la disposición (132) independiente de las otras fuentes de luz en la disposición, caracterizado porque: La disposición (132) de las fuentes de luz (26, 134) es una disposición bidimensional (132) de filas (136) y columnas (138) de fuentes de luz (26, 134); y La luz de cada fuente de luz (26, 134) en una misma fila (136) ilumina la superficie de sensor (32) con sustancialmente un mismo ángulo de incidencia.

公开(公告)号：DE60232689D1

公开(公告)日：2009-07-30

申请号：DE60232689

申请日：2002-12-25

Applicant: BIO RAD LABORATORIES

Inventor： RAN BOAZ ,  NOTCOVICH ARIEL G ,  LIPSON ARIEL ,  NIMRI SHAY ,  LIPSON STEPHEN G ,  LIPSON DORON

IPC: G01N21/55 ,  G01J3/30 ,  G01N21/05

Abstract: An SPR sensor comprising a thin conducting layer comprising at least one conductive element formed on a surface of a transparent substrate, a light source that illuminates an interface between the conducting layer and the substrate, a photosensitive surface that generates signals from light reflected from the interface, a flow cell formed with at least one flow channel having a lumen defined by a wall formed from an elastic material and from a region of the conducting layer, and at least one hollow fluid-providing flow control apparatus having a lumen and an orifice communicating with its lumen. Fluid flow is enabled between the flow channel and the lumen of the flow control apparatus by forcing an end of the flow control apparatus through the elastic material so that the orifice communicates with the flow channel lumen.

公开(公告)号：AT434175T

公开(公告)日：2009-07-15

申请号：AT02808314

申请日：2002-12-25

Applicant: BIO RAD LABORATORIES

Inventor： RAN BOAZ ,  NOTCOVICH ARIEL ,  LIPSON ARIEL ,  NIMRI SHAY ,  LIPSON DORON

IPC: G01N21/55 ,  G01J3/30 ,  G01N21/05

Abstract: An SPR sensor comprising a thin conducting layer comprising at least one conductive element formed on a surface of a transparent substrate, a light source that illuminates an interface between the conducting layer and the substrate, a photosensitive surface that generates signals from light reflected from the interface, a flow cell formed with at least one flow channel having a lumen defined by a wall formed from an elastic material and from a region of the conducting layer, and at least one hollow fluid-providing flow control apparatus having a lumen and an orifice communicating with its lumen. Fluid flow is enabled between the flow channel and the lumen of the flow control apparatus by forcing an end of the flow control apparatus through the elastic material so that the orifice communicates with the flow channel lumen.