公开(公告)号：CA2275853A1

公开(公告)日：2000-01-09

申请号：CA2275853

申请日：1999-06-21

Applicant: BIO RAD LABORATORIES

Inventor： BINDER STEVEN R ,  IKEDA BRYAN H ,  SCOLARI CAROLINE

IPC: G01N33/53 ,  G01N33/68 ,  G01N1/28 ,  G01N1/36 ,  G01N1/40

Abstract: The present invention is generally directed to the analysis of biological samples. More particularly, the present invention is directed to automated sample analysis for paraproteins using immunosubtraction, capillary electrophoresis and Fourier transformation analysis.

公开(公告)号：CA2297092C

公开(公告)日：2003-11-25

申请号：CA2297092

申请日：1998-07-21

Applicant: BIO RAD LABORATORIES

Inventor： SCOLARI CAROLINE ,  LIKUSKI ROBERT K ,  BINDER STEVEN R

IPC: G01N27/447

Abstract: Identification and quantification of paraproteins in a sample is achieved by Fourier analysis of mobility-based electropherograms obtained from capillary electrophoresis. The use of a computer algorithm to analyze capillary electrophoresis data, provides the clinician with methods of detecting level s of paraproteins in serum as low as 0.05 g/dL. Additionally, an individual paraprotein can be located on an electropherogram and used to monitor its increased or decreased production in an individual.

公开(公告)号：AU8571998A

公开(公告)日：1999-02-10

申请号：AU8571998

申请日：1998-07-21

Applicant: BIO RAD LABORATORIES

Inventor： BINDER STEVEN R ,  SCOLARI CAROLINE ,  LIKUSKI ROBERT K

IPC: G01N27/447 ,  G01N27/26

Abstract: Identification and quantification of paraproteins in a sample is achieved by Fourier analysis of mobility-based electropherograms obtained from capillary electrophoresis. The use of a computer algorithm to analyze capillary electrophoresis data, provides the clinician with methods of detecting levels of paraproteins in serum as low as 0.05 g/dL. Additionally, an individual paraprotein can be located on an electropherogram and used to monitor its increased or decreased production in an individual.

公开(公告)号：CA2275853C

公开(公告)日：2002-06-11

申请号：CA2275853

申请日：1999-06-21

Applicant: BIO RAD LABORATORIES

Inventor： BINDER STEVEN R ,  IKEDA BRYAN H ,  SCOLARI CAROLINE

IPC: G01N33/53 ,  G01N33/68 ,  G01N1/28 ,  G01N1/36 ,  G01N1/40

Abstract: The present invention is generally directed to the analysis of biologic al samples. More particularly, the present invention is directed to automated sample analysis for paraproteins using immunosubtraction, capillary electrophoresis and Fourier transformation analysis.

公开(公告)号：CA2297092A1

公开(公告)日：1999-01-28

申请号：CA2297092

申请日：1998-07-21

Applicant: BIO RAD LABORATORIES

Inventor： SCOLARI CAROLINE ,  BINDER STEVEN R ,  LIKUSKI ROBERT K

IPC: G01N27/447

Abstract: Identification and quantification of paraproteins in a sample is achieved by Fourier analysis of mobility-based electropherograms obtained from capillary electrophoresis. The use of a computer algorithm to analyze capillary electrophoresis data, provides the clinician with methods of detecting levels of paraproteins in serum as low as 0.05 g/dL. Additionally, an individual paraprotein can be located on an electropherogram and used to monitor its increased or decreased production in an individual.

公开(公告)号：EP1047931A4

公开(公告)日：2004-04-21

申请号：EP98936864

申请日：1998-07-21

Applicant: BIO RAD LABORATORIES

Inventor： BINDER STEVEN R ,  SCOLARI CAROLINE ,  LIKUSKI ROBERT K

IPC: G01N27/447 ,  G01N27/26 ,  G01N33/561 ,  G01N33/574 ,  G01N33/68 ,  G06F17/14

CPC classification number: G01N27/44721 ,  G01N27/44717

Abstract: Identification and quantification of paraproteins in a sample is achieved by Fourier analysis of mobility-based electropherograms obtained from capillary electrophoresis. The use of a computer algorithm to analyze capillary electrophoresis data, provides the clinician with methods of detecting levels of paraproteins in serum as low as 0.05 g/dL. Additionally, an individual paraprotein can be located on an electropherogram and used to monitor its increased or decreased production in an individual.