公开(公告)号：CA2509461C

公开(公告)日：2007-07-31

申请号：CA2509461

申请日：1998-02-26

Applicant: BIO RAD LABORATORIES

Inventor： HEFFELFINGER DAVID M ,  VAN HORN CRAIG

IPC: G01N27/447 ,  G01N21/63 ,  G01N37/00

Abstract: A method and apparatus for correcting the non-uniformities in the lens assembly of an electrophoresis apparatus is provided. In one aspect, a look-up table is created based on non-uniformities at different aperture and magnification settings (Figure 5). In another aspect, a calibration standard with a uniform emittance is used to correct non-uniformities. In yet another aspect, a beam splitter or mirror is used to create a connection data file for non-uniformities in the light source.

公开(公告)号：CA2283210C

公开(公告)日：2006-07-04

申请号：CA2283210

申请日：1998-02-26

Applicant: BIO RAD LABORATORIES

Inventor： VAN HORN CRAIG ,  HEFFELFINGER DAVID M

IPC: G01N27/447 ,  G01N21/63 ,  G01N37/00

Abstract: A method and apparatus for correcting the non-uniformities in the lens assembly of an electrophoresis apparatus is provided. In one aspect, a look-up table is created based on non-uniformities at different aperture and magnification settings (Figure 5). In another aspect, a calibration standard with a uniform emittance is used to correct non-uniformities. In yet another aspect, a beam splitter or minor is used to create a correction data file for non-uniformities in the light source.

公开(公告)号：CA2283210A1

公开(公告)日：1998-09-17

申请号：CA2283210

申请日：1998-02-26

Applicant: BIO RAD LABORATORIES

Inventor： HEFFELFINGER DAVID M ,  VAN HORN CRAIG

IPC: G01N21/63 ,  G01N27/447 ,  G01N37/00

Abstract: A method and apparatus for correcting the non-uniformities in the lens assembly of an electrophoresis apparatus is provided. In one aspect, a look-up table is created based on non-uniformities at different aperture and magnification settings (Figure 5). In another aspect, a calibration standard with a uniform emittance is used to correct non-uniformities. In yet another aspect, a beam splitter or mirror is used to create a correction data file for non-uniformities in the light source.

公开(公告)号：DE69842076D1

公开(公告)日：2011-02-10

申请号：DE69842076

申请日：1998-02-24

Applicant: BIO RAD LABORATORIES

Inventor： HEFFELFINGER DAVID M ,  VAN HORN CRAIG

IPC: G01N27/26 ,  G01N21/64 ,  G01N27/447

公开(公告)号：CA2509461A1

公开(公告)日：1998-09-17

申请号：CA2509461

申请日：1998-02-26

Applicant: BIO RAD LABORATORIES

Inventor： VAN HORN CRAIG ,  HEFFELFINGER DAVID M

IPC: G01N21/63 ,  G01N27/447 ,  G01N37/00

Abstract: A method and apparatus for correcting the non-uniformities in the lens assembly of an electrophoresis apparatus is provided. In one aspect, a look-up table is created based on non-uniformities at different aperture and magnification settings (Figure 5). In another aspect, a calibration standard with a uniform emittance is used to correct non-uniformities. In yet another aspect, a beam splitter or mirror is used to create a connection data file for non-uniformities in the light source.

公开(公告)号：CA2282298A1

公开(公告)日：1998-09-17

申请号：CA2282298

申请日：1998-02-24

Applicant: BIO RAD LABORATORIES

Inventor： VAN HORN CRAIG ,  HEFFELFINGER DAVID M

IPC: G01N27/447

Abstract: A method and apparatus for achieving uniform illumination in an electrophoresis apparatus is provided. Uniform illumination allows quantitative measurements of anelectrophoresis gel to be made, thus increasing the information which can be obtained from an electrophoretic analysis. Uniform illumination is achieved by scanning the light source (505), preferably in a trans-illumination mode, across the sample gel in a direction perpendicular to the axis of the source. The light source is comprised of one or more light bulbs (505) placed in a light tray (503). Variations in light intensity near the source end portions may be minimized using a variety of techniques including extended light bulbs, filters, reflectors, diffusers, or supplemental sources.

公开(公告)号：CA2509470C

公开(公告)日：2006-11-07

申请号：CA2509470

申请日：1998-02-26

Applicant: BIO RAD LABORATORIES

Inventor： HEFFELFINGER DAVID M ,  VAN HORN CRAIG

IPC: G01N27/447 ,  G01N21/63 ,  G01N21/64 ,  G01N37/00

Abstract: A method and apparatus for correct- ing the non-uniformities in the lens assem- bly of an electrophoresis apparatus is pro- vided. In one aspect, a look-up table is cre- ated based on non-uniformities at different aperture and magnification settings (Figure 5). In another aspect, a calibration standard with a uniform emittance is used to correct non-uniformities. In yet another aspect, a beam splitter or mirror is used to create a correction data file for non-uniformities in the light source.

公开(公告)号：CA2282298C

公开(公告)日：2006-09-19

申请号：CA2282298

申请日：1998-02-24

Applicant: BIO RAD LABORATORIES

Inventor： HEFFELFINGER DAVID M ,  VAN HORN CRAIG

IPC: G01N27/447

Abstract: A method and apparatus for achieving uniform illumination in an electrophoresis apparatus is provided. Uniform illumination allows quantitative measurements of anelectrophoresis gel to be made, thus increasing the information which can be obtained from an electrophoretic analysis. Uniform illumination is achieved by scanning the light source (505), preferably in a trans-illumination mode, across the sample gel in a direction perpendicular to the axis of the source. The light source is comprised of one or more light bulbs (505) placed in a light tray (503). Variations in light intensity near the source end portions may be minimized using a variety of techniques including extended light bulbs, filters, reflectors, diffusers, or supplemental sources.

公开(公告)号：CA2509470A1

公开(公告)日：1998-09-17

申请号：CA2509470

申请日：1998-02-26

Applicant: BIO RAD LABORATORIES

Inventor： HEFFELFINGER DAVID M ,  VAN HORN CRAIG

IPC: G01N21/63 ,  G01N27/447 ,  G01N37/00

Abstract: A method and apparatus for correct- ing the non-uniformities in the lens assem- bly of an electrophoresis apparatus is pro- vided. In one aspect, a look-up table is cre- ated based on non-uniformities at different aperture and magnification settings (Figure 5). In another aspect, a calibration standard with a uniform emittance is used to correct non-uniformities. In yet another aspect, a beam splitter or mirror is used to create a correction data file for non-uniformities in the light source.

公开(公告)号：EP0966673A4

公开(公告)日：2002-08-14

申请号：EP98910066

申请日：1998-02-24

Applicant: BIO RAD LABORATORIES

Inventor： HEFFELFINGER DAVID M ,  VAN HORN CRAIG

IPC: G01N27/447 ,  G01N27/26 ,  G01N21/64

CPC classification number: G01N27/44721

Abstract: A method and apparatus for achieving uniform illumination in an electrophoresis apparatus is provided. Uniform illumination allows quantitative measurements of anelectrophoresis gel to be made, thus increasing the information which can be obtained from an electrophoretic analysis. Uniform illumination is achieved by scanning the light source (505), preferably in a trans-illumination mode, across the sample gel in a direction perpendicular to the axis of the source. The light source is comprised of one or more light bulbs (505) placed in a light tray (503). Variations in light intensity near the source end portions may be minimized using a variety of techniques including extended light bulbs, filters, reflectors, diffusers, or supplemental sources.

Abstract translation: 提供了一种用于在电泳装置中实现均匀照明的方法和装置。 均匀照射可以定量测量电泳凝胶，从而增加电泳分析的信息。 通过扫描光源（505），优选以透射照明模式，在垂直于光源轴线的方向上穿过样品凝胶来实现均匀照射。 光源由放置在光盘（503）中的一个或多个灯泡（505）组成。 使用各种技术（包括扩展灯泡，滤波器，反射器，扩散器或补充源）可以使靠近源端部分的光强度变化最小化。