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Patent Agency Ranking
公开(公告)号：AU2015283850A1
公开(公告)日：2016-12-15
申请号：AU2015283850
申请日：2015-07-02
Applicant: BOARD OF REGENTS UNIVERSITY OF TEXAS SYSTEM
Inventor： CZAKO BARBARA , LIU GANG , THEROFF JAY , HERRERA ZACHARY , YAU ANNE , DI FRANCESCO MARIA EMILIA , JONES PHILIP , HEFFERNAN TIMOTHY , HAMILTON MATTHEW , KANG ZHIJUN , SOTH MICHAEL P , BURKE JASON P , LE KANG , CARROLL CHRISTOPHER LAWRENCE , PALMER WYLIE , LEWIS RICHARD , MCAFOOS TIMOTHY
IPC: C07D401/06 , A61K31/4439 , C07D417/14
Abstract: Disclosed herein are compounds and compositions useful in the treatment of GLS I mediated diseases, such as cancer, having the structure of Formula I. Methods of inhibition GLS I activity in a human or animal subject are also provided. Accordingly, the inventors herein disclose new compositions and methods for inhibiting glutaminase activity. The present disclosure relates to new heterocyclic compounds and compositions, and their application as pharmaceuticals for the treatment of disease. Methods of inhibition of GLS 1 activity in a human or animal subject are also provided for the treatment of diseases such as cancer.
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公开(公告)号：AU2015283850B2
公开(公告)日：2020-06-04
申请号：AU2015283850
申请日：2015-07-02
Applicant: BOARD OF REGENTS UNIVERSITY OF TEXAS SYSTEM
Inventor： DI FRANCESCO MARIA EMILIA , JONES PHILIP , HEFFERNAN TIMOTHY , HAMILTON MATTHEW , KANG ZHIJUN , SOTH MICHAEL P , BURKE JASON P , LE KANG , CARROLL CHRISTOPHER LAWRENCE , PALMER WYLIE , LEWIS RICHARD , MCAFOOS TIMOTHY , CZAKO BARBARA , LIU GANG , THEROFF JAY , HERRERA ZACHARY , YAU ANNE
IPC: C07D401/06 , A61K31/4439 , C07D417/14
Abstract: Disclosed herein are compounds and compositions useful in the treatment of GLS I mediated diseases, such as cancer, having the structure of Formula I. Methods of inhibition GLS I activity in a human or animal subject are also provided. Accordingly, the inventors herein disclose new compositions and methods for inhibiting glutaminase activity. The present disclosure relates to new heterocyclic compounds and compositions, and their application as pharmaceuticals for the treatment of disease. Methods of inhibition of GLS 1 activity in a human or animal subject are also provided for the treatment of diseases such as cancer.
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公开(公告)号：BR112016030730A2
公开(公告)日：2017-08-22
申请号：BR112016030730
申请日：2015-07-02
Applicant: BOARD OF REGENTS UNIVERSITY OF TEXAS SYSTEM
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公开(公告)号：AU2016287661A1
公开(公告)日：2018-01-04
申请号：AU2016287661
申请日：2016-06-30
Applicant: BOARD OF REGENTS UNIVERSITY OF TEXAS SYSTEM
Inventor： LEWIS RICHARD THOMAS , JONES PHILIP , PETROCCHI ALESSIA , REYNA NAPHTALI , HAMILTON MATTHEW , SOTH MICHAEL J , HEFFERNAN TIMOTHY , HAN MICHELLE , BURKE JASON P
IPC: C07D207/00 , A61K31/501 , C07D417/14
Abstract: Disclosed herein are compounds and compositions useful in the treatment of GLSl mediated diseases, such as cancer, having the structure of Formula (I). Methods of inhibition GLSl activity in a human or animal subject are also provided.
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公开(公告)号：AU2016287661B2
公开(公告)日：2020-07-16
申请号：AU2016287661
申请日：2016-06-30
Applicant: BOARD OF REGENTS UNIVERSITY OF TEXAS SYSTEM
Inventor： LEWIS RICHARD THOMAS , JONES PHILIP , PETROCCHI ALESSIA , REYNA NAPHTALI , HAMILTON MATTHEW , SOTH MICHAEL J , HEFFERNAN TIMOTHY , HAN MICHELLE , BURKE JASON P
IPC: C07D207/00 , A61K31/501 , C07D417/14
Abstract: Disclosed herein are compounds and compositions useful in the treatment of GLSl mediated diseases, such as cancer, having the structure of Formula (I). Methods of inhibition GLSl activity in a human or animal subject are also provided.
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